宁远保安地区基性─超基性火山岩基本特征

本文论述了保安地区火山岩的地质、岩石、副矿物、岩石化学、微量元素、稀土元素、稳定同位素、火山岩相及火山机构等特征。并对其演化规律、形成机制与成矿作用的关系，作了初步探讨。     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

基于荧光原理的叶绿素a传感器校准方法研究

利用传感器对水体叶绿素a 浓度进行原位测量是获取实时、连续、长时间序列数据的重要手段。本文在对RBR 传感器和ECO（Environmental Characterization Optics）传感器进行原理分析和线性度、稳定性、重复性等基本性能测试的基础上，利用单一藻种培养液和2020年南海北部海域现场数据校准传感器，并对新的传感器校准系数进行验证。结果表明：两台传感器使用新系数比原出厂系数的叶绿素a 浓度测量准确度有明显提高。RBR 传感器现场数据校准系数的计算结果与叶绿素a 标准值误差最小，平均绝对误差从1.93 μg/L 减小到0.35 μg/L，平均相对误差从55.1%减小到10.9%；ECO 传感器藻液系数明显优于出厂系数和现场数据校准系数的计算结果，平均绝对误差从1.76 μg/L 减小到0.59 μg/L，平均相对误差从50.3%减小到15.1%。传感器测量准确度的提高，可为海洋环境监测、海洋生态灾害预警等工作获取真实可靠数据提供支撑。     

基于分块分形编码的多姿态、表情人脸图像检索

利用图像分形编码中定义域块和最小均方误差一一对应的特点，提出了1种基于分形编码的多姿态、表情的人脸图像检索方法。该方法将待检索图像分割为相同大小的值域块，然后将每一值域块按给定的定义域块进行分形编码，得到最小均方误差，计算该最小均方误差与图像库中最小均方误差的欧氏距离。将待检索图像所有值域块的欧氏距离求平均，此平均欧氏距离较小的几幅图像即为检索出的图像。实验证明该方法能够准确地检索出图像库中存储的同一人的不同姿态、表情的图像。     

Freshening of the Intermediate Waters in the Northern South China Sea over the PastSix Decades

The properties of salinity in the South China Sea (SCS), a significant marginal sea connecting the Pacific andIndian Oceans, are greatly influenced by the transport of fresh water flux between the two oceans. However, the long-termchanges in the intermediate water in the SCS have not been thoroughly studied due to limited data, particularly in relationto its thermodynamic variations. This study utilized reanalysis data products to identify a 60-year trend of freshening in theintermediate waters of the northern South China Sea (NSCS), accompanied by an expansion of low-salinity water. Thestudy also constructed salinity budget terms, including advection and entrainment processes, and conducted an analysis ofthe salinity budget to understand the impacts of external and internal dynamic processes on the freshening trend of theintermediate water in the NSCS. The analysis revealed that the freshening in the northwest Pacific Ocean and theintensification of intrusion through the Luzon Strait at intermediate levels are the primary drivers of the salinity changes inthe NSCS. Additionally, a weakened trend in the intensity of vertical entrainment also contributes to the freshening in theNSCS. This study offers new insights into the understanding of regional deep sea changes in response to variations in boththermodynamics and oceanic dynamic processes.     

基于网络药理学与分子对接技术探讨青蛇方外用治疗湿疹的作用机制

目的：基于网络药理学与分子对接技术探讨青蛇方外用治疗湿疹的作用机制。方法：应用TCMSP和UniProt数据库平台查询青蛇方组方的有效活性成分及靶基因,与疾病靶基因取交集后构建蛋白质-蛋白质相互作用(PPI)网络;应用DAVID数据库,对潜在核心作用靶点基因进行基因本体（GO）功能、京都基因与基因组百科全书（KEGG）通路富集分析。利用分子对接原理论证青蛇方生物活性成分与核心靶点的分子结合能力。结果：筛选出青蛇方有效成分63种,作用靶点99个;主要有β-谷甾醇、2,4,7-三羟基-9,10-二氢菲、靛蓝素、豆甾醇、色氨酸等关键成分;转录因子AP-1（JUN）、肿瘤坏死因子（TNF）、原癌基因（RELA）、干扰素γ（IFNG）、转化生长因子-β1（TGF-β1）等核心基因。关键信号通路有癌症信号通路、恰加斯病通路、弓形体病通路、脂质和动脉粥样硬化通路等,分子对接结果显示活性成分与核心靶点基因结合能力较强。结论：青蛇方外用可以通过多种活性成分、多种通路有效抑制免疫炎症反应,促进免疫系统正常运行,从而达到治疗湿疹的目的。     

To afforest the desert with the technology of peat composed of rotten mosses and the sustainable development of the oases

Only by providing the good conditions for the growth of plants can a favorable ecologicalenvironment on which human beings rely for existence be created. The upside-down-T dou-ble-layer water-conserving afforestation way is developed according to the situation of the short-age of water resources, low soil fertility and vast land in the arid areas. The characteristics of theafforestation way are to change the microenvironment in the root area of the plants, provide thefavorable conditions for the growth of plants, and reduce the necessary conditions for the growth ofplants in large areas in the arid regions. Meanwhile, the size of its water-conserving layer can bechanged according to the size of the planted trees. The different ways of the bottom wa-ter-conserving layer can be used according to the requirements. The afforestation way is suitablefor planting trees on a small scale and also for afforesting on a large scale under the adverse cir-cumstances in the arid areas, and has been effectively used in the afforestation in the hinterland ofTaklamakan Desert and the southern marginal zone of Gurbantonggut Desert. The prospects ofthe afforestation way are broad in afforestation and desertification control in the desert regions.     

几何光学冠层反射建模中的光谱分量特征的参数化(英文)

该文用几何光学与辐射传输混合模型研究不连续植被冠层的几何光学反射模型的四分量（承照树冠、承照地面、阴影树冠、阴影地面）的参数化。用一个修正的均匀介质层路径散射（反射与传输）参数的解析算法估计路径散射参数（反射与传输），其中也考虑了冠层间隙的影响。光谱分量特征是不连续植被冠层的传输与反射，背景反照率，以直射光通量与天空漫射光通量比例的函数。光谱分量特征的模型与在美国缅因州Ｈｏｌａｎｄ采集的针叶林数据吻合。基于ＬｉＳｔｒａｈｌｅｒ几何光学相互遮蔽模型，用参数化的光谱分量特征对老松林和老云杉林的方向反射进行估计，其结果与在不同太阳与观测方向上的ＰＡＲＡＢＯＬＡ测量值匹配得很好。