肝素酶Ⅰ对合成的肝素五糖的酶解作用及对其抗Xa因子活性的影响

研究肝素酶Ⅰ(来源于Flavobacterumheparinase，EC4.2.2.7)对人工合成的且含有与抗凝血酶Ⅲ特定结合位点的肝素五糖(SHP)的酶解作用，并对酶解作用的动力学进行研究。利用强阴离子高效液相色谱(SAX-HPLC)对酶解混合物进行分离，利用质谱(ESIMS)和核磁共振波谱(1H-NMR)技术对得到的二糖和三糖的结构进行确证。研究结果表明，这种被作为肝素反向试剂的肝素酶Ⅰ可水解人工所合成的肝素五糖，从而使之丧失抗Xa因子活性。     

碳水化合物的组合合成

碳水化合物的组合合成是一项新兴技术，该技术可以在短时间内合成大量用于进行生物活性筛选的寡糖及拟糖物。液相与固相合成技术可以极大地加快药物研究与开发进程。作者针对该技术在碳水化合物合成方面的研究进展情况进行讨论。     

扇贝裙边酶水解工艺条件的研究

扇贝在加工完干贝后,大量的含有较高营养价值的扇贝裙边有待利用。本文就扇贝裙边利用不同蛋白酶的水解工艺条件进行了较深入的探讨,以期找出扇贝裙边酶水解的最佳工艺条件。     

特定海域台风路径在中,低层环境场上的简明指征

本文用合成分析方法，研究了台风（热带气旋）各种不同路径中，低层环境高度场和风场上的差异，提出了可用于业务科指征，经独立样本预报试验表明这些简明指征有较好的预报能力。对这些简明指征可用行业务预报的理论依据和局限性也作了粗略讨论。     

我国海水制盐工艺改革的设计研究

从技术上和工艺上的可能性、可行性和合理性，论证了海水制盐工艺改革的必要性，并且提出了实现海水制盐工艺改革的各种设计方案。它对我国的海水制盐工业的发展将具有深远意义。     

耳突麒麟菜卡拉胶提取工艺条件的优化选择

通常,由于C_6和C_2上硫酸酯的存在,未经碱处理的耳突麒麟莱藻体中所含的卡拉胶的凝胶强度低。为提高产品凝胶强度,扩大应用范围,已有不少学者对“碱改性”处理工艺进行过大量研究。作者在实验中直接采用NaOH溶液于不同温度条件下处理菲律宾     

Carbon and oxygen isotopic composition of car- bonate cements of different phases in terrigenous siliciclastic reservoirs and significance for their origin： A case study from sandstones of the Triassic Yanchang Formation, southwestern Ordos Basin, China

Early carbonate cements in the Yanchang Formation sandstones are composed mainly of calcite with relatively heavier carbon isotope （their δ^18O values range from -0.3‰- -0.1‰） and lighter oxygen isotope （their δ^18O values range from -22.1‰- -19.5‰）. Generally, they are closely related to the direct precipitation of oversaturated calcium carbonate from alkaline lake water. This kind of cementation plays an important role in enhancing the anti-compaction ability of sandstones, preserving intragranular volume and providing the mass basis for later disso- lution caused by acidic fluid flow to produce secondary porosity. Ferriferous calcites are characterized by relatively light carbon isotope with δ^13C values ranging from -8.02‰ to -3.23‰, and lighter oxygen isotope with δ^18O values ranging from -22.9‰ to -19.7‰, which is obviously related to the decarboxylation of organic matter during the late period of early diagenesis to the early period of late diagenesis. As the mid-late diagenetic products, ferriferous cal- cites in the study area are considered as the characteristic authigenic minerals for indicating large-scaled hydrocarbon influx and migration within the clastic reservoir. The late ankerite is relatively heavy in carbon isotope with δ^13C values ranging from -1.92‰ to -0.84‰, and shows a wide range of variations in oxygen isotopic composition, with δ^18O values ranging from -20.5‰ to -12.6‰. They are believed to have nothing to do with decarboxylation, but the previously formed marine carbonate rock fragments may serve as the chief carbon source for their precipitation, and the alkaline diagenetic environment at the mid-late stage would promote this process.     

南京市地下管线非开挖工艺应用规划研究

本文通过对非开挖技术规划、管理方面所暴露出的一些问题进行分析,提出了建立非开挖管理、评价系统的思想。经过分析制定了一系列的评价指标并提出了相关建议。