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21.
A.F. Velegrakis M.I. VousdoukasA.M. Vagenas Th. KarambasK. Dimou Th. Zarkadas 《Coastal Engineering》2007
This short contribution reports the results of a field study on the nearshore characteristics of waves generated by both conventional and high speed passenger ferries. The field observations took place in the late summer of 2005, at a beach close to the port of Mytilene (Island of Lesbos, Greece), and involved the visual observation of ship waves, using digital video recordings and image processing techniques. The results showed that passage of the fast ferry was associated with a longer, more complex and energetic nearshore event; this event not only did include higher nearshore waves (up to 0.74 m) and was organised in different wave packets, but it was also an order of magnitude longer (∼ 680 s) than the conventional ferry event. Regarding the effects on beach sediment dynamics, the fast ferry waves were estimated to be very efficient in mobilising the nearshore sediments in contrast to those of the conventional ferry. The fast ferry service appears to generate daily prolonged nearshore events, which contain waves with higher energy than those expected from the normal summer wind wave regime of the area; these events also include some high and very steep waves, which can be particularly erosive. Therefore, fast ferry wakes may have considerable impacts on the seasonal beach sediment dynamics/morphodynamics and the nearshore benthic ecology, as well as they may pose significant risks to bathers, affecting the recreational use of the beaches exposed to fast ferry traffic. Finally, the study has shown that satisfactory field observations of the nearshore characteristics of ship-generated (and wind) waves can be obtained using inshore deployments of calibrated poles, digital video cameras and appropriate image processing algorithms. 相似文献
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Low-frequency damping of a moored semisubmersible drilling platform was obtained from numerical extinction tests simulated in still water and in regular waves and from mean wave drift forces calculated at zero forward speed. The influence of drag forces was represented by the modified Morison equation. The platform as used for the 18th ITTC Comparative Mooring Study was analyzed in irregular beam waves. The computed time series of sway as well as the corresponding sway response spectrum compared favourably with model test measurements, demonstrating that this procedure to determine low-frequency damping can be effective. 相似文献
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目的:基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法:使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用(PPI)网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果:共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6(IL-6)、肿瘤坏死因子(TNF)、丝氨酸/苏氨酸蛋白激酶1(AKT1)、白细胞介素-1B(IL-1B)等;主要涉及肿瘤坏死因子(TNF)、白细胞介素-17(IL-17)、磷脂酰肌醇3-激酶(PI3K)/蛋白激酶B(Akt)等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论:该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。 相似文献
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Pyruvate kinase (PK) activity measurements are used to assess the role of carbohydrates in global feeding of mesozooplankton communities inhabiting an estuary plume. As a consequence of a remarkably low freshwater discharge rate, the sea surface layers of the area under estuarine influence showed a very moderate salinity fall and a nearly total depletion in nitrates, whereas higher levels of these nutrients were found in deeper, more saline, layers. Small-scale PK activity variations in mesozooplankton appear to be closely correlated to nitrate integration values within the water column. The results were analysed in comparison with literature reports. The study produced a coherent overall interpretation, which strongly supports the reliability of this new biochemical tool in detecting assimilation of trace carbohydrates in the diet of mesozooplankton. 相似文献
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The properties of salinity in the South China Sea (SCS), a significant marginal sea connecting the Pacific andIndian Oceans, are greatly influenced by the transport of fresh water flux between the two oceans. However, the long-termchanges in the intermediate water in the SCS have not been thoroughly studied due to limited data, particularly in relationto its thermodynamic variations. This study utilized reanalysis data products to identify a 60-year trend of freshening in theintermediate waters of the northern South China Sea (NSCS), accompanied by an expansion of low-salinity water. Thestudy also constructed salinity budget terms, including advection and entrainment processes, and conducted an analysis ofthe salinity budget to understand the impacts of external and internal dynamic processes on the freshening trend of theintermediate water in the NSCS. The analysis revealed that the freshening in the northwest Pacific Ocean and theintensification of intrusion through the Luzon Strait at intermediate levels are the primary drivers of the salinity changes inthe NSCS. Additionally, a weakened trend in the intensity of vertical entrainment also contributes to the freshening in theNSCS. This study offers new insights into the understanding of regional deep sea changes in response to variations in boththermodynamics and oceanic dynamic processes. 相似文献
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山西能源重化工基地建设关系到全国四个现代化的实现,被列为国家重点建设工程,制定了《山西能源重化工基地综合规划》。本文分析了80年代山西省经济建设的成就与问题。提出了“整体创新,综合开发”,把山西能源重化工基地建设成内陆经济开放区的战略大思路,为此,90年代应完成11项大型经济战略工程,同时展望了经济发展改革前景。 相似文献