β-1, 4-半乳糖基转移酶抑制剂的研究进展

β-1,4-半乳糖基转移酶(β-1,4-GalT)抑制剂的研究是当今糖化学和糖生物学的前沿研究领域之一。本文就β-1,4-GalT抑制剂(包括供体类似物、受体类似物、过渡态类似物)的设计、合成及活性评价诸方面予以综述。     

光测力学方法在薄壁钢-混凝土组合结构节点试验中的应用

应用光测力学中的数字散斑图像处理技术和网格法对对称荷载下的薄壁钢-混凝土组合结构节点的试验进行了监测,得到了节点的一些相关位移,并与百分表法测量的结果进行了比较。结果表明,两种方法用于轻钢组合结构构件的位移测量是足够精确的,可以根据试验的不同要求选择测量方法。     

黄土高原西部白草塬剖面L1 和S1 记录的古地磁场特征

文章详细介绍了黄土高原西部白草塬剖面L1和S1的高精度岩石磁学和古地磁学结果,讨论了白草塬剖面记录古地磁场的特征,从古地磁学角度探讨白草塬剖面黄土沉积的连续性.白草塬剖面黄土沉积物中,磁铁矿和磁赤铁矿是主要的亚铁磁性矿物,粗粒的碎屑磁铁矿是其天然剩磁和特征剩磁的主要载体.白草塬剖面L1和S1没有记录任何地磁漂移.其中,L1没有记录Mono Lake或Laschamp地磁漂移的原因可归结于黄土沉积物堆积过程的不连续性和/或粗颗粒载磁矿物的重磁化,但前者是主要原因,而堆积过程的不连续性是导致S1没有记录Blake地磁漂移的主要原因.因此,白草塬剖面的L1和S1分别存在约2000年和 4000～6000年的沉积不连续.     

胶东半岛大磨曲家金矿床成矿流体物理化学条件演化

胶东大磨曲家金矿床流体包裹体包括水溶液包裹体、富CO2包裹体和高盐卤水包裹体3种类型,前两者发育较多,高盐卤水包裹体发育极少。流体包裹体显微测温及盐度、密度、压力估算显示,水溶液包裹体均一温度为98~376℃,据冰点温度估算,盐度为0.53%~8.28%,水溶液包裹体均一压力低于50×105Pa;富CO2包裹体完全均一温度为255~348℃,盐度为2.42%~11.43%,均一压力为1 000×105~2 500×105Pa;富CO2包裹体中CO2均一温度为23.0~32.4℃,指示该类包裹体可能含有数量不等的CH4或H2S。静水压力体制下,根据纯CO2包裹体均一压力估算成矿深度约为1 km。在270℃左右,均一压力从富CO2包裹体到水溶液包裹体急剧降低,指示成矿流体在270℃左右可能发生过一次减压沸腾过程,成矿流体盐度和密度在270℃左右也有显著的变化。因此,沸腾作用及其引起的成矿流体物理化学条件的急剧变化可能是导致大磨曲家金矿床成矿物质沉淀的重要机制。     

Environmental Redox Changes of the Ancient Sea in the Yangtze Area during the Ordo-Silurian Transition

Extensive organic-matter （OM） rich facies （black shales） occur in the Ordo-Silurian boundary successions in the Yangtze area, South China. To investigate the redox changes of the Yangtze Sea during the Ordo-Silurian transition, two OM sections （Wangjiawan in Yichang, Hubei Province, and Sanjiaguan in Zhangjiajie, Hunan Province） straddling the Ordo-Silurian boundary are studied. The measurements finished in this study include contents of the total organic carbon （TOC）, pyrite sulphur, and different species of Fe, including dithionite-extractable Fe （FED）, pyrite Fe （FeP）, HCl-extractable Fe （FeH）, and total Fe （FeT）, in black shales, as well as other redox proxies, such as the SIC ratio, the ratio between highly reactive Fe （FeHR = FeD ＋ FeP） and FeT, and the FeP/（FeP ＋ FeH） ratio, known as the degree of pyritization （DOP）. In the Wangjiawan section, the Middle Ashgill sediments have high FeHR/FeT ratios （0.20-0.77; avg. 0.45）, high DOP values （0.21-0.72; avg. 0.54）, and a relatively constant sulfur content independent of the organic carbon content. By the contrast, the mid-early Hirnantian deposits generally have low FeHR/FeT ratios （0.10-0.35; avg. 0.21）, low DOP values （0.11- 0.40; avg. 0.28）, and SIC values are clustering on the normal marine value （SIC = 0.36）. The late Hirnantian and early Rhuddanian deposits, similar to those of the Middle Ashgill deposits, are characterized by high FeHR/FeT ratios （0.32-0.49; avg. 0.41）, high DOP values （0.46-0.68; avg. 0.53） and fairly constant sulfur contents. These data suggest the occurrences of marine anoxia on the Yangtze Sea shelf during intervals of the Mid Ashgill, Late Hirnantian and Early Rhuddanian, and ventilated and oxygenated marine conditions during the mid-early Hirnantian time. The mid-early Hirnantian ventilated event was concomitant with the global glacial period, likely resulted from the glacio-eustatic sea-level fall and subsequent circulation of cold, dense oxygenated waters     

Isotopes and Geochronology of the Meixian-type Pb-Zn-(Ag)Deposits,Central Fujian Rift,South China:Implications for Geological Events

Central Fujian Rift is another new and important volcanogenic massive sulfide Pb-Zn polymetallic metallogenetic belt. In order to find out the material genesis and mineralization period of Meixian-type Pb-Zn-Ag deposits, S and Pb isotope analysis and isotope geochronology of ores and wall rocks for five major deposits are discussed. It is concluded that the composition of sulfur isotope from sulfide ore vary slightly in different deposits and the mean value is close to zero with the 834S ranging from -3.5‰ to ＋5.6‰ averaging at ＋2.0‰, which indicates that the sulfur might originate from magma or possibly erupted directly from volcano or was leached from ore-hosted volcanic rock. The lead from ores in most deposits displays radioactive genesis character （206pb/204pb〉18.140, 207Pb/204pb〉15.584, 208pb/204pb〉38.569） and lead isotope values of ores are higher than those of wall rocks, which indicates that the lead was likely leached from the ore-hosted volcanic rocks. Based on isotope data, two significant Pb-Zn metallogenesis are delineated, which are Mid- and Late-Proterozoic sedimentary exhalative metailogenesis （The single zircon U-Pb, Sm-Nd isochronal and Ar-Ar dating ages of ore- hosted wall rocks are calculated to be among 933-1788 Ma.） and Yanshanian magmatic hydrothermal superimposed and alternated metallogenesis （intrusive SHRIMP zircon U-Pb and Rb-Sr isochronal ages between 127-154 Ma）.     

鄂尔多斯地块早白垩世构造-热事件:杭锦旗玄武岩的Ar-Ar年代学证据

在鄂尔多斯地块北部杭锦旗黑石头沟,于下白垩统砂岩之上发现了一层玄武岩。其SiO2(46.93%)较低而碱含量(K2O+Na2O=6.21%)较高,组合指数σ=8.0,含标准矿物Ne,属于碱性橄榄玄武岩。Ar-Ar激光阶段加热定年结果表明,该玄武岩具有126.2±0.4Ma的Ar-Ar年龄。年龄数据表明杭锦旗黑石头沟玄武岩形成于早白垩世,反映鄂尔多斯地块在早白垩世发生了一次构造-岩浆-热事件,这与华北、乃至整个中国东部在早白垩世发生了较普遍的构造-岩浆-热事件具有一致性。这次构造-岩浆-热事件可能引起深部流体自地下深部上涌及在地块内部运移,为各种成矿元素的迁移、沉淀、富集和成矿创造了合适条件。     

南海北部深水盆地沉积-构造的差异性及其油气意义

南海北部深水区自西向东依次分布着琼东南盆地、珠江口盆地、台西南盆地等新生代被动陆缘盆地,这些盆地经历了大致相当的从裂陷到坳陷的构造演化史,但在张裂活动过程中存在着明显的沉积-构造的差异性。构造沉降特征分析显示:在同一构造带上自西向东有盆地主要构造沉降发生的时段逐步变晚的趋势;在不同构造带上自北向南有盆地主要构造沉降发生的时段逐步变晚的趋势。这种沉积-构造的差异性对烃源岩的发育类型、分布及生储盖组合等方面有明显的控制作用,表现为:裂谷期构造沉降幅度大的盆地,陆相烃源岩发育,以陆生陆储陆盖型成藏组合为主;裂后期构造沉降幅度大的盆地,海相烃源岩发育规模较大,海生海储海盖型成藏组合及混生海储海盖型生储盖组合所占分量逐渐增多。推测渐新统湖相-湖沼相及海陆过渡相源岩和中新统海相烃源岩应是南海北部深水区油气的主要来源,陆生海储海盖型、海生海储海盖型及混生海储海盖型生储盖组合应是深水区基本生储盖组合类型。     

数字填图系统（RGMAP）在金厂矿区大比例尺填图中的应用

计算机辅助地质填图系统(RGMAP软件),通过建立PRB数字填图过程及其相应的数据模型,把地质数据采集的过程延伸到野外,真正实现了地学数据获取全过程的数字化,实现了地质填图从手工到计算机化的质的飞跃.但该系统的研制初衷是为在区域调查中地质调查服务的,而对大例尺的填图尚未开展过研究.这里以在黑龙江省东宁县金厂矿区开展的1∶10 000大比例尺数字填图为例,总结出利用该系统在大比例尺数字填图中的主要方法步骤和注意事项.     

福建建阳大金山铅锌矿床地球物理化学异常特征

大金山铅锌矿位于泰宁一政和北东东向铜多金属成矿带上,是该成矿带主要的矿种之一,也是闽北地区一个较有价值的矿床。矿床产于早元古代南山组上段,受燕山期北东东向构造控制,属中低温热液充填交代型矿床。