Canny算子对人工标志中心的亚像素精度定位

在使用圆型人工标志的计算机视觉检测中,人工标志的识别率和中心定位精度直接影响到检测的整体精度.传统的中心定位算法对人工标志识别率低、中心定位精度差,已不能满足精密检测的要求.文中采用Canny算子对带有圆形人工标志的数字图像进行边缘分割,通过模式识别方法、最小二乘拟合方法计算人工标志中心.该方法解决了标志识别率低的问题,提高了标志图像中心定位精度.其精度可达到亚像素级,能够满足高精度计算机视觉测量的要求.     

尺度分层多阈值结合SVM分类的热红外舰船识别

针对尺度自适应选择分层多阈值方法,有时检测目标不完整且存在较多虚警目标等问题,提出了一种基于尺度分层多阈值和SVM分类相结合的舰船目标检测与识别方法。首先使用尺度自适应分层多阈值方法进行初检测;其次根据样本学习生成舰船目标特征及最佳分类特征组合;最后使用SVM样本学习分类实现舰船目标检测与识别。实验结果表明,该方法比单一使用样本分类法降低了虚警率,提高了检测效率,能在近岸舰船目标与背景对比度较低的情况下实现虚假目标有效剔除,且在突堤式码头停放的舰船目标识别中更有效和更稳定。     

基于网络药理学和分子对接技术探究柯里拉京治疗卵巢癌的关键靶点及分子机制

目的：采用网络药理学和分子对接技术相结合的方法探究柯里拉京（Cor）治疗卵巢癌的关键作用靶点和分子机制。方法：利用PharmMapper、TargetNet及Swiss Target Prediction在线工具预测Cor的作用靶点,通过OMIM、TTD、CTD、DisGenet、PharmGKB及MalaCards数据库获取卵巢癌相关的疾病靶点,并将药物靶点与疾病靶点取交集得到Cor治疗卵巢癌的预测靶点。借助STRING数据库、Cytoscape 软件构建蛋白质-蛋白质相互作用（PPI）网络,并采用CentiScape插件筛选出PPI网络中的核心靶点。运用GEPIA和Kaplan-Meier Plotter在线平台分别对这些核心靶点进行基因表达差异分析和生存分析,以明确Cor治疗卵巢癌的关键靶点。利用DAVID数据库进行基因本体（GO）功能及京都基因与基因组百科全书（KEGG）通路富集分析。运用Autodock Vina软件进行正向分子对接,预测关键靶点和Cor之间的结合活性。结果：Cor治疗卵巢癌的预测作用靶点共24个,其中RAC-α丝氨酸/苏氨酸蛋白激酶(AKT1)、表皮生长因子受体(EGFR)、雌激素受体1(ESR1)、原癌基因酪氨酸蛋白激酶(SRC)是Cor治疗卵巢癌的关键靶点,主要涉及血管内皮生长因子(VEGF)信号通路、缺氧诱导因子-1(HIF-1)信号通路及叉头样转录因子(FoxO)信号通路,可能通过调控细胞凋亡、细胞增殖、血管内皮细胞迁移等生物过程而发挥治疗卵巢癌的作用。分子对接结果显示,Cor与预测靶点之间具有较好的亲和力,表明通过网络药理学预测作用靶点的方法具有良好的可靠性。结论：Cor是通过多靶点、多通路的协同作用来干预多个生物过程,从而发挥其抗卵巢癌疗效,为进一步研究其治疗卵巢癌的分子机制提供了新的线索。     

透射式微焦点X射线源钨-金刚石靶材的制备及其性能研究

本文采用磁控溅射镀膜技术制备了钨-金刚石透射靶材,借助电子扫描电镜对靶材的钨薄膜进行微观形貌分析。同时借助YXLON光机,研究自制靶材在X射线出射率及其产生X射线所需消耗功率和寿命等性能,并与YXLON原带靶材进行性能比较。研究表明,采用磁控溅射制备的钨薄膜与YXLON靶材上的钨薄膜具有相似的表面形貌;在YXLON光机相同工作条件下,自制靶材的X射线出射率略高于YXLON原带靶材的X射线出射率的1%,二者辐射X射线所需的功率相差无几,自制靶材的寿命要长于YXLON靶材的。这表明自制钨-金刚石靶材能够满足微焦点射线源所需的高质量靶材的应用要求。      

基于水下多目标定位的目标识别和辨析处理

在水下多目标的定位过程中,对不同目标发射源的标识和分辨是非常关键的一部分。介绍一种方法,即在目标发射数据的文件头加上一个目标号进行标识。在数据处理中采用三级顺序的数据分离,层层提取,能够分辨出不同目标定位所需的数据。     

九瑞矿集区三维电性结构研究及找矿意义

九瑞矿集区作为全国重点整装勘查区之一,深部找矿工作一直是研究重点和热点.本文在综合分析研究区区域地质资料、对典型地层和岩石标本进行电阻率参数测试和统计分析的基础上,利用研究区面积性AMT数据进行三维电性结构研究.为获得AMT最佳反演参数,选择一条典型AMT剖面开展二维非线性共轭梯度(NLCG)反演,进而总结出利用TM极化模式数据、拉格朗日乘子等于3的二维反演方案.综合利用地质、钻探和电性特征对全区23条AMT剖面进行二维约束反演,并将所有测线的电阻率反演结果三维网格化,得到了研究区的三维电性结构.最后,我们通过对三维电性结构的综合分析,确定研究区地下地层、岩体展布、断裂构造分布特征以及基底起伏情况.与已知矿床对比,我们发现浅部北西断裂与北东向区域性深部断裂交汇处、基底隆起凹槽边缘以及岩体边缘为成矿有利区.     

Mineralogical characterization of potential targets for the ASTEX mission scenario

In-situ investigation of asteroids is the next logical step in understanding their exact surface mineralogy, petrology, elemental abundances, particle size distribution, internal structure, and collisional evolution. Near-Earth asteroids (NEAs) provide us with ample opportunities for in-situ scientific exploration with lower Δv requirements and subsequently lower costs than their main belt counterparts. The ASTEX mission concept aims at surface characterization of two compositionally diverse NEAs, one with primitive and the other with a strong thermally evolved surface mineralogy. Here we present the first results of our ground-based characterization of potential ASTEX mission targets using the SpeX instrument on the NASA IRTF. Of the four potential targets we characterized, two (1991 JW and 1998 PA) have compositions similar to ordinary chondrite mineralogy. The other two targets (1994 CC and 1999 TA10) are thermally evolved objects with igneous formation histories. While 1994 CC is a triplet system and thus very challenging to orbit the V-type NEA, 1999 TA10 is the most interesting scientific ASTEX target identified so far.     

Breeding,settlement and survival of barnacles at artificially modified shore levels at Leigh,New Zealand

The breeding and settlement seasons of the intertidal barnacles Chamaesipho brunnea, C. columna and Elminius plicatus were determined, and experiments using cages on the shore to examine barnacle survival and growth rate at four levels were carried out at Leigh during 1964–66.

Chamaesipho brunnea bred in spring and summer; C. columna and E. plicatus bred throughout the year, but settled intermittently. When protected from predators and from overgrowth by algae, all three species survived at levels lower than normal. At higher levels C. columna, E. modestus, Balanus trigonus and Tetraclita purpuraseens survived for significant periods (C. brunnea occurs naturally higher on the shore than the highest experimental level).     

Predicting sediment inputs to aquatic ecosystems across England and Wales under current environmental conditions

The awareness of water quality issues has never been higher. As part of its continuing strategic diffuse pollution policy support, ADAS recently undertook to identify catchments across England and Wales that could potentially fail recently proposed suspended sediment yield targets under current environmental conditions. The total suspended sediment loads (SSL) delivered to all rivers were assumed to comprise contributions from diffuse sources in the agricultural and urban sectors, as well as from eroding channel banks and point sources represented by sewage treatment works (STWs). Diffuse agricultural sediment loss to rivers was predicted using the PSYCHIC model. Corresponding inputs from diffuse urban sources were estimated on the basis of an Event Mean Concentration (EMC) methodology. Channel bank sediment inputs were calculated using a prototype national scale model, while point source sediment contributions were based on a register of consented effluent discharges. Modelled SSL were validated (r²=68%) against PARCOM data (1999–2003) for the delivery of sediment to different regions of the UK maritime area. The results of the validation were considered to be realistic for a national scale predictor. The modelling exercise suggested that those catchments currently at risk of exceeding proposed suspended sediment yield critical thresholds are largely confined to upland areas across Wales and northwest England and the chalklands of southern and eastern England.     

Delineation of potential exploration targets based on 3D geological modeling: A case study from the Laoangou Pb-Zn-Ag polymetallic ore deposit,China

The Laoangou Pb-Zn-Ag polymetallic ore deposit (LAG) is a hydrothermal vein-type deposit in the East Qinling polymetallic metallogenic belt, which is controlled by NW-, NE- and nearly SN-trending faults and mainly hosted in the dolomite marble of Meiyaogou and Baishugou formations within the Luanchuan ore district (LOD). Although district-scale metallogenic prediction related to the Pb-Zn-Ag deposits in the LOD has been attempted, there have been no studies to formulate a detailed deposit-scale metallogenic prediction of the Pb-Zn-Ag deposit in 3D space. Here we selected the LAG to formulate a metallogenic prediction model for Pb-Zn-Ag deposit based on data from 1:10,000 scale geological map, and 66 boreholes and 39 sections of exploration lines on 1:1000 scale, to extract the salient spatial features of the deposit. We apply ordinary weights and weighted weights of evidence, followed by boosted weights of evidence, logistic regression and information entropy for integrating the features of the ore deposit for exploration targeting. The C–V fractal method is applied to classify the probabilities. Accordingly, three levels of exploration targets are delineated: the first level targets are mainly distributed in the periphery of known orebodies (M2, M3, II-3 and VI), which are also located in the ore-controlling strata and fault zones; the second level targets are located in the region of known orebodies, indirectly confirming that the prediction result is reliable; and the third level targets, which are mainly located at the contact between ore-controlling strata and metagabbro bodies, offer new targets for exploration in this ore district. Combining our results obtained in this study with those in previous studies, we provide some guidelines for exploration targets in the Pb-Zn-Ag deposits in the LOD, which might help in more effectively delineating the target zones.