南海南部晚中新世的放射虫及其环境探讨

南海是东亚古季风产物的主要沉积盆地，保存着比陆地更加完整和连续的沉积记录。详细分析了ODP1143号钻井晚中新世的放射虫化石群，主要根据标志种Diartus petterssoni,D.hughesi和Stichocorys delmontensis等的分布特征，分别建立了南海南部晚中新世的RN6，RN7和RN8等3个放射虫化石带，并讨论了其地层年龄。探讨了以地层中放射虫的丰度变化特征等在南海南部作为东亚古夏季风活动替代性指标的可能性，初步说明东亚古夏季风可能早于8．7Ma B.P．出现，约在8．24Ma B.P.强化达到高峰，认为与印度季风的出现几乎同步或略早。     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

Variational iteration solving method for El Nio phenomenon atmospheric physics of nonlinear model

1 IntroductionThe El Ni’o atmospheric physics oscillation is anabnormal phenomenon involved in the tropical Pacificocean- atmosphere interactions. Studies on the El Ni(ophenomenon are very attractive (Lin et al., 2000; Linet al., 2001, 2002; Wang, 2001; Feng et al., 2001;Feng et al., 2002; Liu et al., 2002; Wei and Chen,2003; Xie et al., 2002; Zhu et al., 2002; Pu et al.,2003; Gu et al., 2004; Yu and Liu, 2004). Lin and Mo(2004), Mo and Lin (2004) and Mo et al. (2004) alsostudied a s…     

Pathogens and pathogenicity to Penaeus orientalis Kishinouye

ＰａｔｈｏｇｅｎｓａｎｄｐａｔｈｏｇｅｎｉｃｉｔｙｔｏＰｅｎａｅｕｓｏｒｉｅｎｔａｌｉｓＫｉｓｈｉｎｏｕｙｅＩＮＴＲＯＤＵＣＴＩＯＮＢａｃｔｅｒｉａ，ｅｓｐｅｃｉａｌｌｙｖｉｂｒｉｏｓａｒｅｏｎｅｏｆｔｈｅｍａｊｏｒｐａｔｈｏｇｅｎｓｔｏｃｕｌｔｕｒ...     

DISTRIBUTION, ECOLOGY AND RESOURCE CONSERVATION OF THE SPOTTED SEAL IN THE HUANGHAI AND BOHAI SEAS

The Phoca largha is found in the coastal waters of China from the Huanghai Sea and Bohai Sea to the northern part of East China Sea. Its breeding ground is situated in ice packs in the Liaodong Gulf., from about 40°10′ to 40°45′ N, from 121 °15′ to 122°E. At the breeding season, male and female seals in pairs form many family groups. The pup is born with white lanugo fur on ice packs in Liaodong Gulf during a period from January to the middle of February, and usually carried by its mother on her back to run away. However, from February to March, it could be caught around some islands in Bohai Strait. In recent years, these species resources have been reduced rapidly. It must be strengthened to protect the seals from extinction.     

ELASTIC CLASSIFICATION OF MODIFIED WATER MASS IN SHALLOW SEA

In this paper, the principle and steps for differentiating water masses by fuzzy cluster method are introduced, and a scalar formula based on Euclidean distance and a method for determining objectively the number of water masses by F-test are proposed. Consequently, a method and specific steps for differentiating modified water masses in shallow sea according to fuzzy elastic classification are given. Computation of the membership degree in which each sample belongs to every water mass determines conveniently and quantitatively the cores, boundaries of water masses and mixed zones. An example for the Huanghai Sea and East China Sea is shown and compared with previous results.     

关于多项式特征值的条件数

Tisseur(2000)研究了非齐次多项式特征值问题的条件数，所得结果的不足是对无穷特征值必须另外处理；Declieu和Tisseur(2003)运用微分几何方法研究了齐次多项式特征值问题的条件数，所得结果的不足之处是与系数矩阵的尺度化(scaling)有关。这两种条件数都有各自的应用范围。本文基于投影尺度引入齐次多项式特征值问题的条件数，其优点是与系数矩阵的尺度化无关，因而也许会有较广泛的应用。     

A Preliminary Study of Quantitative Distribution of Benthic Animals in the East China Sea Continental Shelf and Its Adiacent Waters

In October and November of 1977 and September and October of 1978,a quantitative survey of benthic animals was conducted in the East China Sea Continental Shelf and its adjacent waters(26°00'-34°00'N,124°00'-129°00'E,water depth 39-1550m),where 307 stations were dredged and 1200 samples collected.     

病毒膜蛋白及其表达和纯化技术的研究进展

病毒囊膜是包膜病毒除核衣壳外的另一主要成分。它主要由多种蛋白质构成，称为膜蛋白，膜蛋白以单聚体，二聚体，三聚体，甚至更多的聚合体的形式存在，具有中和抗体，与靶细胞受体结合，凝集红细胞，诱导细胞融合等多种功能，膜蛋白可采用将其基因整合入载体，并在昆虫细胞，哺乳细胞或细菌中获得体外表达，膜蛋白可在去污剂的作用下形成蛋白质－脂－去污剂的复合物而被溶解，其中去污剂的临界微团浓度，亲水物－亲脂物平衡值，荷电、紫外穿透性等是选择合适去污剂的主要参考因子，溶解后的膜蛋白多利用聚丙烯酰胺凝胶电泳、凝胶过滤层析，离子交换层析，亲和层析，高效液相层析等技术并结合梯度离心；分级沉淀等进行分离、纯化。     

健康型牛蛙饲料养殖牛蛙的试验

本研究采用5种中草药添加剂配方的膨化饲料进行了为期36d的牛蛙养殖对比试验.结果表明，饲料中添加有中草药制剂的日摄食量明显大于对照组，日增重显著比对照组的高.而且大大加快了生长速度，缩短养殖周期，同时减少了染病机率，牛蛙体色鲜艳、光泽度极佳.