An aromatase inhibitor and tamoxifen decrease plasma levels of o,p'-DDT and its metabolites in Nile tilapia (Oreochromis niloticus)

The objective of this study was to determine if tamoxifen or an aromatase inhibitor (4-hydroxyandrostenedione; 4-OHA) affected plasma concentrations of o,p' -DDT and its metabolites, o,p'-DDD and o,p'-DDE, in mature tilapia. Male and female tilapia were injected 6 times intraperitoneally with o,p'-DDT (40 mg/kg) alone or in combination with 4-OHA (2 mg/kg) over a 12 day period. An additional group of male fish was injected with tamoxifen (5 mg/kg) plus o,p'-DDT. At the end of the treatment period, plasma samples were extracted and analyzed by GC/ECD. Females injected only with o,p'-DDT had significantly higher levels of o,p'-DDT compared with males. Interestingly, females and males treated concomitantly with o,p'-DDT and 4-OHA or tamoxifen had significantly lower concentrations of plasma o,p'-DDT (about 50%) compared with fish treated with only o,p'-DDT. These initial results suggest that an interaction between endocrine-active compounds occurs in vivo in tilapia and may involve alterations in metabolism of o,p'-DDT.     

Resonant structure of the outer asteroid belt

An analysis of ordered and chaotic regions of motion in the outer asteroid belt has shown that once the eccentricity of Jupiter is introduced the chaotic regions of the circular model are quite easily depleted. This suggests that also objects in neighbouring regions must be strongly perturbed. Therefore it is not surprising that many outer belt asteroids have been reported in the literature as resonant or anyway dynamically protected. By using the planar elliptic restricted 3-body model we have investigated the motion of outer belt asteroids which had not been suspected to librate. We find 3 cases of libration and 11 cases of e, coupling that can be explained within the theory of secular resonances. It is thus established that in the outer belt only resonant and dynamically protected asteroids can have lifetimes of the same order as the age of the Solar System.     

Flow time estimation with spatially variable hillslope velocity in ungauged basins

The automated spatial estimation of the hillslope runoff dynamics is used as a valuable tool for the estimation of the travel time distribution (flow time), a major factor for the hydrologic prediction in ungauged basins. In fact, while the flow time function is usually obtained by rescaling the flow paths with constant channel and hillslope velocities, in this work a spatially distributed kinematic component, as a function of terrain features and in particular slope and land use, is implemented and its influence on the hydrologic response is tested by means of the Width Function Instantaneous Unit Hydrograph (WFIUH) framework. Hillslope surface flow velocities are evaluated by applying different uniform flow formulas within an automated DEM-based (terrain analysis) algorithm. A comparison test of the performances of the Manning, Darcy, Maidment and Soil Conservation Service uniform flow equations is performed for several case studies in Italy pertaining to different climatic and geomorphic conditions. Results provide new insights for a better understanding of the flow time function also introducing a more parsimonious and physically-based calibration scheme of the WFIUH.     

Impacts of maintenance channel dredging in a northern Adriatic coastal lagoon. II: Effects on macrobenthic assemblages in channels and ponds

Coastal lagoons are ephemeral habitats whose conservation requires human intervention, such as maintenance dredging of inner channels. Dredging can reduce the abundance of benthic species due to the removal of individuals with the sediment, modify sediment properties, and resuspend fine sediment, nutrients and pollutants, which can lead to eutrophication, hypoxic events and increasing toxicity. Both direct effects in the dredged channel and possible indirect effects in surrounding shallow areas could be expected. This study assesses the effects of the channel maintenance dredging, performed between October 2004 and August 2005, on the invertebrate assemblages both in channels and adjacent ponds in the northern Adriatic coastal lagoon of Pialassa Baiona. The lagoon is affected by eutrophication, chemical and thermal pollution from wastewater treatment and power plants. Three impacted sites were located in the dredged channel and three in the adjacent interconnected shallow water ponds, while three non-impacted sites were located in a channel and in a pond far from the dredged area. Replicate samples were collected from each site one time before and one time after the dredging operations. Despite the extent of the intervention, effects of the dredging on macrobenthic assemblages were detected only within the dredged channel, while in the surrounding ponds no clear and unequivocal effects were found. In particular the dredging could have promoted the increase of the abundance of the polychaete Streblospio shrubsolii in the southern and central parts of the dredged channel and the increase in abundance of the amphipod Corophium insidiosum in the northern side, compared to the controls. Instead, species diversity was reduced in the central and northern parts of the dredged channel. These effects on the macrobenthic invertebrate assemblages could be related to the observed changes of sediment characteristics, contamination and toxicity. Overall, direct effects on benthic assemblages in the dredged channels were more detectable than the possible secondary effects in the surrounding shallow ponds, where the higher spatial heterogeneity can mask any relevant effects.     

Seismic behavior of single‐story asymmetric‐plan buildings under uniaxial excitation

The critical parameters that influence the nonlinear seismic response of asymmetric‐plan buildings are identified by evaluating the effects of different asymmetries that may characterize the structure of a building as well as exploring the influence of the ground motion features. First, the main findings reported in the literature on both the linear and nonlinear dynamic response of asymmetric‐plan buildings are presented. The common findings and the conflicting conclusions reached in different investigations are pointed out. Then, the results of comprehensive nonlinear dynamic analyses performed for evaluating the seismic response of systems characterized by different strength and stiffness configurations, representative of a large class of asymmetric‐plan buildings, are reported. Findings from the study indicate that the building response changes when moving from the linear to the nonlinear range, so that the seismic behavior of asymmetric‐plan buildings, apart from the source of asymmetry, can be always classified as irregular. Additionally, it was observed that as the seismic demands cause amplification of system nonlinearity with increasing earthquake intensity, the maximum displacement demand in the different resisting elements tends to be reached with the same deformed configuration of the system. The resultant of the seismic forces producing such a maximum demand is located at the center of resistance and corresponds to the collapse mechanism of the system that provides the maximum lateral strength in the exciting direction of the seismic action. Copyright © 2008 John Wiley & Sons, Ltd.     

Potential changes in extremes and links with the Southern Annular Mode as simulated by a multi-model ensemble

We assess the likely changes in climate extremes under enhanced greenhouse gases over the southern extratropics, with emphasis in southern South America and sub-Antarctic seas, through the analysis of extreme indices measured from models participating in the IPCC 4th Assessment Report. We discuss how the anthropogenic climate change under A1B scenario influences both the patterns of mean change of extreme indices and the likelihood of occurrence of severe extreme indices. The likelihood of occurrence of a year with a large number of days with “warm” minimum temperatures is estimated to increase by a factor of 4 by the end of this century over most of the southern extratropics. By that time, the risk of “severe” precipitation intensity is projected to rise in most areas with the exception of the subtropical anticyclones, which experience particularly strong drying. Over the Southern Ocean this likelihood has increased to over 60%. Corresponding estimates of the changing likelihood for very long dry spells show a banded structure with positive ratios to the north of about 50° S and negative ratios in the sub Antarctic seas. In southern South America this risk about doubled between present and future climates. Then, we explore if the Southern Annular Mode influences the occurrence of severe extreme indices during the period 2070–2099. Its positive phase inhibits the extremely warm minimum temperatures in the Southern Ocean, with the exception of the eastern Bellingshausen Sea, and favors severe frost days to the north of the Ross Sea. Temperature indices show very little change induced by the SAM to the north of 50° S. Severe dry spells are inhibited during the positive phase along the sub Antarctic seas, while the mid-latitudes, including most of Patagonia, show the opposite behaviour. The Southern Ocean reveals a non-uniform distribution with both increases and decreases in the occurrence of heavier precipitation during positive SAM.     

Engineering geomorphological characterisation of the Vajont Slide,Italy, and a new interpretation of the chronology and evolution of the landslide

Although the 1963 Vajont Slide in Italy has been extensively studied for over 50 years, its regional geological and geomorphological context has been neglected. In this paper, we use field observations and remote sensing data to elucidate the interaction between endogenic and exogenic processes that brought the north slope of Monte Toc to failure. We present the first detailed pre- and post-failure engineering geomorphology maps of the slide area. The maps delineate two main landslide blocks, several sub-blocks, compressional and extensional zones, and secondary failures in the deposit. The maps provide new insights into the kinematics, dynamics and evolution of the slide. Finally, we discuss the origin of Vajont Gorge and a prehistoric failure that occurred at the same location as the 1963 slide. We propose, as part of a newly developed multi-stage landscape evolution sequence, that the prehistoric failure was a deep-seated gravitational slope deformation (sackung) that initiated during deglaciation and continued to slowly move until the catastrophic failure in 1963. We argue that the gorge was created by these deep-seated slow movements.     

Integration error over very long time spans

The main limit to the time span of a numerical integration of the planetary orbits is no longer set by the availability of computer resources, but rather by the accumulation of the integration error. By the latter we mean the difference between the computed orbit and the dynamical behaviour of the real physical system, whatever the causes. The analysis of these causes requires an interdisciplinary effort: there are physical model and parameters errors, algorithm and discretisation errors, rounding off errors and reliability problems in the computer hardware and system software, as well as instabilities in the dynamical system. We list all the sources of integration error we are aware of and discuss their relevance in determining the present limit to the time span of a meaningful integration of the orbit of the planets. At present this limit is of the order of 10⁸ years for the outer planets. We discuss in more detail the truncation error of multistep algorithms (when applied to eccentric orbits), the coefficient error, the method of Encke and the associated coordinate change error, the procedures used to test the numerical integration software and their limitations. Many problems remain open, including the one of a realistic statistical model of the rounding off error; at present, the latter can only be described by a semiempirical model based upon the simpleN ² formula (N=number of steps, =machine accuracy), with an unknown numerical coefficient which is determined only a posteriori.     

Reporting negative results to stimulate experimental hydrology: discussion of “The role of experimental work in hydrological sciences – insights from a community survey”*

ABSTRACT

Experimental work in hydrology is in decline. Based on a community survey, Blume et al. showed that the hydrological community associates experimental work with greater risks. One of the main issues with experimental work is the higher chance of negative results (defined here as when the expected or wanted result was not observed despite careful experimental design, planning and execution), resulting in a longer and more difficult publishing process. Reporting on negative results would avoid putting time and resources into repeating experiments that lead to negative results, and give experimental hydrologists the scientific recognition they deserve. With this commentary, we propose four potential solutions to encourage reporting on negative results, which might contribute to a stimulation of experimental hydrology.