In this age of modern biology, aquatic toxicological research has pursued mechanisms of action of toxicants. This has provided potential tools for ecotoxicologic investigations. However, problems of biocomplexity and issues at higher levels of biological organization remain a challenge. In the 1980s and 1990s and continuing to a lesser extent today, organisms residing in highly contaminated field sites or exposed in the laboratory to calibrated concentrations of individual compounds were carefully analyzed for their responses to priority pollutants. Correlation of biochemical and structural analyses in cultured cells and tissues, as well as the in vivo exposures led to the production and application of biomarkers of exposure and effect and to our awareness of genotoxicity and its chronic manifestations, such as neoplasms, in wild fishes. To gain acceptance of these findings in the greater environmental toxicology community, “validation of the model” versus other, better-established often rodent models, was necessary and became a major focus. Resultant biomarkers were applied to heavily contaminated and reference field sites as part of effects assessment and with investigations following large-scale disasters such as oil spills or industrial accidents.
Over the past 15 years, in the laboratory, small aquarium fish models such as medaka (Oryzias latipes), zebrafish (Danio rerio), platyfish (Xiphophorus species), fathead minnow (Pimephales promelas), and sheepshead minnow (Cyprinodon variegatus) were increasingly used establishing mechanisms of toxicants. Today, the same organisms provide reliable information at higher levels of biological organization relevant to ecotoxicology. We review studies resolving mechanisms of toxicity and discuss ways to address biocomplexity, mixtures of contaminants, and the need to relate individual level responses to populations and communities. 相似文献
Directional samples were taken to study rock magnetism and palaeomagnetic records from the Dong- sheng profile, which is 5 m thick and on the northwest edge of the Bose Basin. Mineralogy and rock magnetism of typical samples indicate that coarse granular titanomagnetite, and fine-grained hematite, superparamagnetic maghemite formed by pedogenesis are in the sediment, which has undergone many transformative processes during different stages of pedogenesis. Parallel samples were taken for thermal demagnetization (TH) (0 to 680℃) and alternating field (AF) demagnetization (0 to 80 mT) respectively. Experimental results of these two kinds of demagnetization illustrate that there are two or more magnetic components in the samples. Intensity of NRM decreases by almost 60% to 90% rapidly when the temperature ranges from 100℃ to 350℃, with a steady magnetic component. It is impossible to analyze the magnetic components at high temperature because those fluctuate widely when the temperature is higher than 400℃. Steady magnetic components from 100℃ to 350℃ indicate that the remanence was mainly carried by fine-grained hematite formed by pedogenesis, reflecting a change in the geomagnetic field while the magnetite was being oxidized into hematite by chemical weathering after deposition. The formative age of the sediments cannot be obtained by magnetic methods in this profile. 相似文献
Based on classic iterative computation results, new equations to calculate the surface turbulent transfer coefficients are
proposed, which allow for large ratios of the momentum and heat roughness lengths. Compared to the Launiainen scheme, our
proposed scheme generates results closer to classical iterative computations. Under unstable stratification, the relative
error in the Launiainen scheme increases linearly with increasing instability, even exceeding 15%, while the relative error
of the present scheme is always less than 8.5%. Under stable stratification, the Launiainen scheme uses two equations, one
for 0 < RiB ≤ 0.08 and another for 0.08 < RiB ≤ 0.2, and does not consider the condition that RiB > 0.2, while its relative errors in the region 0 < RiB ≤ 0.2 exceed 31 and 24% for momentum and heat transfer coefficients, respectively. In contrast, the present scheme uses only
one equation for 0 < RiB ≤ 0.2 and another equation for RiB > 0.2, and the relative error of the present scheme is always less than 14%. 相似文献
This paper presents a case study on the Mogangling landslide and its characteristics and geological mechanism. The Mogangling landslide is a giant rock landslide located at the intersection of Dadu river and Moxi river. It is a landslide triggered by an earthquake with large magnitude that occurred in 18th century. Based on detailed site investigation, it shows the Mogangling landslide developed in the Kangding complex strata, composed of completely decomposed aggregates of massive-block stone, debris and soil with some gravels, pebbles and sand layer found distributed in front of the landslide. The control factor of the deformation of this landslide is the combined effect of Detuo fault which is located under the slope, and the regional stress formed along structural planes as well as the free surfaces formed by river cutting. Therefore, when the Kangding-Moxi earthquake (Ms =7.7) occurred on 1st June, 1786, due to seismic shaking, topographic amplification effects and back slope effects, the Mogangling landslide occurred. The Dadu River is the most important river for hydropower development in China; large-scale seismic landslides along the Dadu River are the most important geological issue during the construction of hydropower stations. Therefore, this research is important from the point of view of economic and social benefits. 相似文献