Protective effects of C-phycocyanin on alcohol-induced acute liver injury in mice

Excessive alcohol consumption leads to liver disease. Extensive evidence suggests that C-phycocyanin (C-PC), a chromophore phycocyanobilin derived from Spirulina platensis, exerts protective effects against chemical-induced organ damage. In this study, we investigated whether C-PC could protect against ethanol-induced acute liver injury. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), total cholesterol (CHOL), low-density lipoprotein (LDL), liver homogenate malondialdehyde (MDA), superoxide dismutase (SOD) content were measured, and pathological examination of liver sections were examined. C-PC showed obvious inhibitory effects on serum ALT, AST, TG, CHOL, LDL and MDA, and SOD content significantly increased in the liver. The structure of hepatic lobules was clear, liver sinus returned to normal, and liver cell cords were arranged in neat rows. Cloudiness, swelling, inflammatory cell infiltration and spotty necrosis of liver cells were significantly reduced. Therefore, C-PC can significantly protect against ethanol-induced acute liver injury.     

Analysis of phenotypic and genetic parameters for growthrelated traits in the half smooth tongue sole, <Emphasis Type="Italic">Cynoglossus semilaevis</Emphasis>

Phenotypic and genetic parameters for growth-related traits in the half-smooth tongue sole, Cynoglossus semilaevis, were estimated in 22 full-sib families produced by normal and neo-male breeding stocks. As phenotypic males with female genotypes, neo-males are harmful in C. semilaevis aquaculture because they reduce overall production. The present study evaluated the difference in the growth-related traits: total length (TL), body weight (BW) and square root of body weight (SQ_BW) at the age of 570 days between normal and neo-male offspring (neo-males used as male parents). The difference in the proportion of females between normal and neo-male offspring was also assessed. Based on the linear mixed model, restricted maximum likelihood (REML) and best linear unbiased prediction (BLUP) were used to estimate various (co)variance components and estimated breeding values (EBVs) of growth-related traits. As a result, all the mean values of the three studied traits were significantly larger in normal offspring than in neo-male offspring. Additionally, the female proportion was significantly larger in normal offspring than in neo-male offspring. Heritability was 0.128±0.066 2 for TL, 0.128±0.065 5 for BW and 0.132±0.062 9 for SQ_BW, all of which were low level heritabilities. The correlation coefficients of EBVs and phenotypic values of the target traits were 0.516 for TL, 0.524 for BW and 0.506 for SQ_BW, all of which were highly significant (P <0.01). Genetic correlations among TL, BW and SQ_BW were positive high (0.921–0.969) and higher than those of phenotype (0.711–0.748), both of which had low standard errors (0.063–0.123 for genotype, and 0.010–0.018 for phenotype). Compared with normal offspring, neo-male offspring have lower breeding values for each studied trait through EBVs comparison. Therefore, neo-male offspring should not be used as broodstock in a C. semilaevis breeding programs.     

Characterizing groundwater/surface-water interactions in the interior of Jianghan Plain,central China

Hydrogeology Journal - Quantifying groundwater/surface-water interactions is essential for managing water resources and revealing contaminant fate. There has been little concern on the exchange...     

Numerical analysis of effect of baffle configuration on impact force exerted from rock avalanches

In mountainous areas, channelized rock avalanches swarm downslope leading to large impact forces on building structures in residential areas. Arrays of rock avalanche baffles are usually installed in front of rigid barriers to attenuate the flow energy of rock avalanches. However, previous studies have not sufficiently addressed the mechanisms of interaction between the rock avalanches and baffles. In addition, empirical design approaches such as debris flow (Tang et al., Quat Int 250:63–73, 2012), rockfall (Spang and Rautenstrauch, 1237–1243, 1988), snow avalanches (Favier et al., 14:3–15, 2012), and rock avalanches (Manzella and Labiouse, Landslides 10:23–36, 2013), which are applied in natural geo-disasters mitigation cannot met construction requirements. This study presents details of numerical modeling using the discrete element method (DEM) to investigate the effect of the configuration of baffles (number and spacing of baffle columns and rows) on the impact force that rock avalanches exert on baffles. The numerical modeling is firstly conducted to provide insights into the flow interaction between rock avalanches and an array of baffles. Then, a modeling analysis is made to investigate the change pattern of the impact force with respect to baffle configurations. The results demonstrate that three crucial influencing factors (baffle row numbers, baffle column spacing, and baffle row spacing) have close relationship with energy dissipation of baffles. Interestingly, it is found that capacity of energy dissipation of baffles increases with increasing baffle row numbers and baffle row spacing, while it decreases with increasing baffle column spacing. The results obtained from this study are useful for facilitating design of baffles against rock avalanches.     

Cyclic degradation and non-coaxiality of soft clay subjected to pure rotation of principal stress directions

Foundation soils are often under non-proportional cyclic loadings. The deformation behaviour and the mechanism of non-coaxiality under continuous pure principal stress rotation for clays are not clearly investigated up to now. In order to study the effect of pure principal stress rotation, a series of cyclic undrained tests on Shanghai soft clay subjected to cyclic rotation of principal stress directions keeping the deviatoric stress constant under the pure rotation condition were conducted using hollow cylinder apparatus. Based on this, the evolutions of excess pore pressure and strains during cyclic loading were investigated, together with the effects of the intermediate principal stress parameter and the deviatoric stress level on stress–strain stiffness and non-coaxiality. The result can provide an experimental basis for constitutive modelling of clays describing the behaviour under non-proportional loadings.     

Soil column infiltration tests on biomediated capillary barrier systems for mitigating rainfall-induced landslides

Rainfall-induced landslide is a common geohazard in tropical and humid regions. Capillary barrier system (CBS) is a popular and widely studied mitigating measure for rainfall-induced landslides. However, several previous studies have shown that the performance of the conventional CBS under intense rainfalls has not been particularly convincing. This paper aims to explore the feasibility and effectiveness of a newly proposed system, known as “biomediated capillary barrier system” (B-CBS) in minimizing water infiltration into soil. A one-dimensional soil column was used to investigate the infiltration characteristics of the proposed system. The results showed that the B-CBS of biomediated residual soil overlying original residual soil (Test IV) could effectively control the infiltration into soil by taking advantage of the less-permeable biomediated soil cover. The B-CBS of biomediated residual soil overlying gravelly sand (Test V) and the three-layered B-CBS of fine sand overlying gravelly sand and biomediated residual soil (Test VI) showed the best performance in terms of minimizing the water infiltration. A suction of about 5 kPa still remained in the soil column after 60 min of infiltration from the ponded water on the soil surface.     

Mechanical behavior and micro-structure of cement kiln dust-stabilized expensive soil

In this study, the effects of cement kiln dust (CKD) on the swelling properties, strength properties, and microstructures of CKD-stabilized expansive soil were investigated. Samples were prepared and stabilized with different CKD content ratios, ranging from 0 to 18% by dry mass. The results obtained show that the maximum swelling pressures decrease exponentially with increases in CKD content. Both the cohesion and unconfined compressive strength (UCS) increase at ratios below 10% CKD and then decrease slightly, above that ratio. CKD can also improve the strength of saturated, expansive soil. There is no visible change of UCS for soil without CKD when cured, while the UCS of a sample with 10% CKD content after curing for 90 days is higher than that after curing for only 1 day. This indicates that CKD can improve the long-term strength of expansive soil. Finally, microstructure analysis reveals that the addition of CKD reduces the montmorillonite content of expansive soil and decreases its swelling properties. The addition of CKD also changes the pore volume distribution, both the size and amount of macro-pores and micro-pores decrease with increase in CKD content. For saturated samples, the size of macro-pores is obviously reduced, while that of micro-pores is slightly increased for both treated and untreated soils. Hydration and saturation processes make the soil structure become dispersive which results in a lower strength, and adding CKD can restrain this process. The suggested optimal CKD content is between 10 and 14% and with a curing time of more than 27 days.     

Carbonate formation mechanism in paleosol sediments of the Bohai Sea coastal zone,China

The Bohai Sea coastal zone of China consists of the Pacific Ocean to the east and Eurasia to the west; hence, this region is influenced by both the ocean and continental landmasses. The carbonate formation mechanism of eolian sediment within this area is poorly understood. The loess-paleosol sediments of the Miaodao stratigraphical section (MDS) contain a record of carbonate changes in this region during the last interglacial period. New insights into regional carbonate formation mechanisms since the last interglacial period were obtained by analyzing the ages of various sedimentary facies in combination with proxy paleoclimatic indices (including average grain size, standard deviation, CaCO₃ content, and clay minerals), as well as via foraminiferal analysis. The results led to three principal findings: (1) The carbonate content change in the MDS was neither controlled by grain size nor affected by minerals. The carbonate change controlled by precipitate leaching in the Loess Plateau region cannot explain the eolian sediments within the Bohai Sea coastal zone. (2) Various subsections contain obvious carbonate content changes caused by foraminiferal deposits atop the eolian sediments, which were deposited by storm surges during a high sea-level period. This increased the carbonate content in the eolian sediments and restricted the carbonate content in the Bohai Sea coastal zone. (3) Newly detected foraminifera of the last interglacial period on the eolian sediment of the MDS were the main source of carbonate content, providing a new understanding of the carbonate formation mechanism in eolian sediments different from that of the Loess Plateau.