辛通畅络法对膜性肾病小鼠TNF-α及IL-10的影响

目的：观察中药复方肾络宁对膜性肾病（MN）模型小鼠TNF-α和IL-10的影响。方法：实验Balb/c小鼠采用阳离子化牛血清白蛋白（C-BSA）诱导MN模型,分为模型组、肾络宁组,另设正常组,以肾络宁为治疗药物,于实验第0周、第3周、第6周末检测各组小鼠尿蛋白及血清TNF-α、IL-10的变化情况。结果：治疗6周后,模型组和肾络宁组小鼠均出现不同程度的尿蛋白排泄量增加,其中肾络宁组较模型组小鼠尿蛋白排泄量减少;与空白对照组比较,模型组、肾络宁组TNF-α表达均不同程度升高,IL-10表达均不同程度降低,其中肾络宁组改善优于模型组,差异均有统计学意义（P<0.05或P<0.01）。结论：肾络宁具有减少MN模型小鼠尿蛋白排泄的作用,其机制可能与调节TNF-α及IL-10的表达相关。     

利用基于环境因子的动态产量模型评估西南大西洋阿根廷滑柔鱼

西南大西洋阿根廷滑柔鱼,Illex argentinus,巴塔哥尼亚南部群体是重要的经济种类。海洋环境因子在柔鱼资源分布中起着重要的作用。本研究利用基于环境因子的动态产量模型评估2000-2010年的滑柔鱼的资源量。假设海洋环境因子（滑柔鱼产卵场最适宜海表温度占比）影响动态产量模型的参数K,DIC值表明在正态分布和均匀分布下均是基于环境因子的评估模型优于基本的动态产量模型。阿根廷滑柔鱼的最大可持续产量（MSY）在351600吨到685 100吨之间,资源生物量在1322400吨到1 803 000吨之间,其捕捞死亡系数均小于F_0.1和F_MSY,资源处在良好状态,没有遭受过度捕捞。本研究为应用环境因子在柔鱼类的资源评估与管理提中供了科学的参考方法。     

东海陆架外缘区构造特征及其成因机制

东海陆架边缘的构造特征记录了有关冲绳海槽张裂过程的关键信息,对于进一步理解海槽的形成演化以及弧后张裂与弧-陆碰撞之间的相互作用至关重要。本文基于多道地震和重磁资料,分析了东海陆架边缘的地形和构造特征,并对冲绳海槽早期张裂过程、北西向断裂带的分隔控制作用、钓鱼岛隆起带南北构造差异和冲绳海槽的向西前展等问题进行了探讨。结果表明,冲绳海槽西侧陆坡存在的分段性,各分段在地形地貌、地层展布和构造特征等方面的不同,体现了其构造演化和现今构造活动性的差异。冲绳海槽中—北段的张裂始于陆架前缘坳陷,在晚中新世向东扩展至整个海槽,晚中新世至今以分散式张裂为主。北西向断裂带对东海陆架边缘不同分段的构造特征和构造活动起到了分隔控制和转换协调作用,控制了不同类型陆坡的形成和发育。受冲绳海槽在全宽度上向西前展的影响,钓鱼岛隆起带南段的基底隆起及其支撑的陆架边缘发生了破坏和沉降,形成基底起伏较大、地形崎岖不平的陆坡。     

一种基于GPU和内存映射文件的高分辨率遥感图像快速处理方法

高分辨率遥感图像处理经常面临程序执行时间过长和内存空间不足的问题,虽然并行计算技术可以提高遥感图像的处理速度,但是无法降低算法占用的巨大内存空间。为了解决这一问题,本文提出了一种利用CUDA和内存映射文件的高分辨率遥感图像快速处理方法,并以K-Means算法为例进行了实现。其中,CUDA技术可以有效利用GPU强大的并行计算能力,而内存映射文件技术降低了磁盘I/O速度较慢对算法性能的影响。实验结果表明,本文方法比传统K-Means聚类算法计算速度提高了30倍左右,内存使用量降低了90%以上。     

A stock assessment for Illex argentinus in Southwest Atlantic using an environmentally dependent surplus production model

The southern Patagonian stock(SPS) of Argentinian shortfin squid, Illex argentinus, is an economically important squid fishery in the Southwest Atlantic. Environmental conditions in the region play an important role in regulating the population dynamics of the I. argentinus population. This study develops an environmentally dependent surplus production(EDSP) model to evaluate the stock abundance of I. argentines during the period of 2000 to 2010. The environmental factors(favorable spawning habitat areas with sea surface temperature of 16–18°C) were assumed to be closely associated with carrying capacity(K) in the EDSP model. Deviance Information Criterion(DIC) values suggest that the estimated EDSP model with environmental factors fits the data better than a Schaefer surplus model without environmental factors under uniform and normal scenarios.The EDSP model estimated a maximum sustainable yield(MSY) from 351 600 t to 685 100 t and a biomass from 1 322 400 t to1 803 000 t. The fishing mortality coefficient of I. argentinus from 2000 to 2010 was smaller than the values of F_(0.1) and F_(MSY). Furthermore, the time series biomass plot of I. argentinus from 2000 to 2010 shows that the biomass of I.argentinus and this fishery were in a good state and not presently experiencing overfishing. This study suggests that the environmental conditions of the habitat should be considered within squid stock assessment and management.     

Binary Star Fractions from the LAMOST DR4

Stellar systems composed of single, double, triple or higher-order systems are rightfully regarded as the fundamental building blocks of the Milky Way. Binary stars play an important role in formation and evolution of the Galaxy. Through comparing the radial velocity variations from multiepoch observations, we analyze the binary fraction of dwarf stars observed with LAMOST. Effects of different model assumptions, such as orbital period distributions on the estimate of binary fractions,are investigated. The results based on log-normal distribution of orbital periods reproduce the previous complete analyses better than the power-law distribution. We find that the binary fraction increases with Teff and decreases with [Fe/H]. We first investigate the relation between α-elements and binary fraction in such a large sample as provided by LAMOST. The old stars with high [α/Fe] dominate with a higher binary fraction than young stars with low [α/Fe]. At the same mass, earlier forming stars possess a higher binary fraction than newly forming ones, which may be related with evolution of the Galaxy.     

Effects of feeding time on complement component C7 expression in Pelteobagrus vachellii subject to bacterial challenge

Journal of Oceanology and Limnology - Shifting the feeding time for fish from daytime to nighttime could alter their digestive behavior, disturb their metabolism, and may affect immune-related...     

Assessment of prospective hazards resulting from the 2017 earthquake at the world heritage site Jiuzhaigou Valley,Sichuan, China

On August 8, 2017, a Ms = 7.0 magnitude earthquake occurred in the Jiuzhaigou Valley, in Sichuan Province, China(N: 33.20°, E: 103.82°). Jiuzhaigou Valley is an area recognized and listed as a world heritage site by UNESCO in 1992. Data analysis and field survey were conducted on the landslide, collapse, and debris flow gully, to assess the coseismic geological hazards generated by the earthquake using an unmanned aerial vehicle(UAV), remote-sensing imaging, laser range finders, geological radars, and cameras. The results highlighted the occurrence of 13 landslides, 70 collapses, and 25 potential debris flow gullies following the earthquake. The hazards were classified on the basis of their size and the potential property loss attributable to them. Consequently, 14 large-scale hazards, 30 medium-sized hazards, and 64 small hazards accounting for 13%, 28%, and 59% of the total hazards, respectively, were identified. Based on the variation tendency of the geological hazards that ensued in areas affected by the Kanto earthquake(Japan), Chi-chi earthquake(Taiwan China), and Wenchuan earthquake(Sichuan China), the study predicts that, depending on the rain intensity cycle, the duration of geological hazard activities in the Jiuzhaigou Valley may last over ten years and will gradually decrease for the following five to ten yearsbefore returning to pre-earthquake levels. Thus,necessary monitoring and early warning systems must be implemented to ensure the safety of residents,workers and tourists during the construction of engineering projects and reopening of scenic sites to the public.     

Estimating the properties of weathered bedrock and pilerock interaction from the geological strength index

The effect of variable rock mass properties on pile-rock interaction poses a great challenge to the design of stabilizing piles and numerical analysis of pile-rock interaction. The paper presents a novel method to estimate the properties of weathered bedrock, which can be applied to routine design of landslide-stabilizing piles for collivial landslides. The Ercengyan landslide located in the Three Gorges Reservoir, China, is the area of interest for this study. A geological investigation and triaxial tests were conducted to estimate the basic parameters, including Geological Strength Index(GSI), uniaxial compressive strength σ_(ci) and Hoek-Brown constant m_i of intact bedrock in the study area. Hoek-Brown criterion was used to estimate mechanical properties of the weathered rock, including elastic modulus E_m, cohesion c, friction angle Φ, and normal ultimate lateral resistance p_(max). A parametric study was performed to evaluate the effect of parameterizations of GSI, σ_(ci) and m_i on the bedrock properties and p-y curves. The estimated rock mass properties were used with PLAXIS 2D software to simulate pile-rock interaction. Effect of GSI on stress at the pile-rock interface and in the rock, pile bending moment, pile shear force, and p-y curve were analysed.     

阿尔金铅、钕、锶、氩、氧同位素研究及其早期演化

根据铅、钕、锶、氩、氧等同位素体系及其年代学研究，阿尔金在其早期演化阶段中存在２７９０—２５９０、１８８３—１７０４、５７５和４７０—４２０Ｍａ４个构造热事件，各自具有不同的性质和时代意义。