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91.
Patterns in the spatial or temporal distribution of genotypes may be indicative of natural selection. Previous work on the woolly mammoth melanocortin-1 receptor (Mc1r) gene identified three polymorphic positions that suggest Pleistocene populations may have harboured both light- and dark-haired mammoths (Rompler et al., 2006, 313: 62). Here, we extend this work and present the first population-level analysis of a functional gene in an extinct species. We genotyped the Mc1r gene in 47 woolly mammoth samples excavated from sites across the central portion of the woolly mammoths’ former range to examine the extent of variation of this polymorphism through time and across space. Only one individual was found to be heterozygous, indicating that the frequency of the ‘light’ mutant allele was very low. We conclude that light-coloured woolly mammoths would have been very rare, and may even have been non-existent if the ‘light’ mutant allele was strongly selected against in its homozygotic form. With the increasing availability of large-scale sequencing technologies, population-level datasets capable of identifying local adaptation will become increasingly attainable.  相似文献   
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Measurement of ecological, climatic and anthropogenic changes underpins the formulation of effective management strategies for sustainable use and protection of the marine environment. Sensors are traditionally used in marine studies to determine physical parameters, but there is increasing demand for real-time information about chemical and biological parameters. These parameters are currently measured in samples collected at sea and subsequently analysed in the laboratory. Biosensors fuse the exquisite sensitivity and specificity of living systems with the processing power of microelectronics to deliver simple, inexpensive measurement systems for use in the field or deployment in situ. While their potential for use in the marine environment is enormous, much published work to date has focussed on applications in freshwater and wastewater. Marine applications pose a substantial challenge in the robustness required for remote application, but recent developments in portable medical devices and receptor design suggest that these demands can now be realistically tackled.  相似文献   
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Records from the Greenland Ice Sheet Project Two ice core are considered in terms of dynamical systems theory and nonlinear prediction. Dynamical systems theory allows us to reconstruct some properties of a phenomenon based only on past behavior without any mechanistic assumptions or deterministic models. A near-term prediction of temperature, including a mean estimate and confidence interval, is made for 800 years into the future. The prediction suggests that the present short-time global warming trend will continue for at least 200 years and be followed by a reverse in the temperature trend.  相似文献   
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Role of water in the origin of podiform chromitite deposits   总被引:2,自引:0,他引:2  
We report experiments in basalt oversaturated with water to duplicate the nodular ore textures of podiform chromitite ores. In immiscible basalt-water systems saturated with olivine and chromite, olivine will reside in the melt while chromite will collect in the fluid phase. Fractionation is physical and is driven by differential wetting properties of melt and fluid against silicate and oxide surfaces. There is no need to suppress olivine from the liquidus of a primitive basaltic melt as suggested by Irvine [Irvine, T.N., Geology 5 (1977) 273-277], to achieve chromite accumulations as observed in natural podiform ore deposits. The results imply that podiform chromitite ores will form where a primitive olivine-chromite-saturated mantle melt is sufficiently water-rich to exsolve a fluid phase during passage through the uppermost mantle. The most likely geodynamic environment for podiform chromite mineralization to take place is a supra-subduction zone setting.  相似文献   
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SHRIMP dating of detrital zircons from sandstones of the Gackowa Formation (Kaczawa Complex, Sudetes, SW Poland) indicates input from late (550–750 Ma) and early Proterozoic to Archaean sources (∼2.0–3.4 Ga, the latter being the oldest recorded age from the Sudetic region). These dates preclude within-terrane derivation from seemingly correlatory acid volcanic rocks of early Palaeozoic age. Rather, they indicate provenance from Cadomian and older rocks that currently form part of other, geographically distant terranes; the most likely source identified to date is the Lusatian Block in the Saxothuringian Zone. Hence, the Gackowa Formation may be late Proterozoic rather than early Palaeozoic in depositional age, possibly coeval with the late Proterozoic (pre-Cadomian) greywackes of Lusatia, being subsequently tectonically interleaved with early Palaeozoic volcanic rocks into the Kaczawa accretionary prism during the Variscan orogeny. However, correlation with the lithologically similar early Ordovician Dubrau Quartzite of Saxothuringia, and so assignation to the early Paleozoic (post-Cadomian) rift succession deposited at the northern margin of Gondwana, cannot yet be precluded.  相似文献   
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Within the International Very Long Baseline Interferometry (VLBI) Service for Geodesy and Astrometry (IVS), long time-series of zenith wet and total troposphere delays have been combined at the level of parameter estimates. The data sets were submitted by eight IVS Analysis Centers (ACs) and cover January 1984 to December 2004. In this paper, the combination method is presented and the time-series submitted by the eight IVS ACs are compared with each other. The combined zenith delays are compared with time-series provided by the International Global Navigation Satellite System (GNSS) Service (IGS), and with zenith delays derived from the European Centre for Medium-Range Weather Forecasts (ECMWF). Before the combination, outliers are eliminated from the individual time-series using the robust BIBER (bounded influence by standardized residuals) estimator. For each station and AC, relative weight factors are obtained by variance component estimation. The mean bias of the IVS ACs’ time-series with respect to the IVS combined time-series is 0.89 mm and the mean root mean square is 7.67 mm. Small differences between stations and ACs can be found, which are due to the inhomogeneous analysis options, different parameterizations, and different treatment of missing in-situ pressure records. Compared to the IGS zenith total delays, the combined IVS series show small positive mean biases and different long-term trends. Zenith wet delays from the ECMWF are used to validate the IVS combined series. Inconsistencies, e.g., long-term inhomogeneity of the in-situ pressure data used for the determination of VLBI zenith delays, are identified.  相似文献   
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