自拟通窍祛瘀汤治疗外伤性气滞血瘀型脑内血肿51例

目的：观察自拟通窍祛瘀汤治疗外伤性气滞血瘀型脑内血肿的临床疗效。方法：选取外伤性气滞血瘀型脑内血肿患者100例,将其随机分为治疗组（51例）和对照组（49例）。2组均予以基础治疗,对照组在基础治疗上加用西医常规治疗,治疗组在对照组基础上加用自拟通窍祛瘀汤口服治疗。治疗2周后观察2组中医证候疗效,治疗前、治疗1周后、治疗2周后观察2组血肿吸收、水肿吸收、神经功能缺失（NIHSS）评分、中医证候积分情况。结果：总有效率治疗组为94.11%（48/51）,明显高于对照组的75.51%（37/49）,2组比较,差异有统计学意义（P＜0.05）。治疗后2组血肿体积、水肿体积、NIHSS评分、中医证候积分均较治疗前减少,且治疗组与对照组治疗后同时间节点比较,差异均有统计学意义（P＜0.05或P＜0.01)。结论：外伤性气滞血瘀型脑内血肿患者在常规治疗的基础上使用自拟通窍祛瘀汤治疗可以促进神经功能恢复,改善中医证候,促进血肿和水肿吸收。     

卫矛醇对C6胶质瘤细胞体外抗癌活性及机制探讨

目的:研究卫矛醇对C6胶质瘤细胞株的体外增殖及凋亡的影响。方法：将C6大鼠胶质瘤细胞随机分为对照组、卫矛醇干预组、卫矛醇+雷帕霉素组、卫矛醇+3-MA组,各组予不同药物孵育,采用MTT法检测卫矛醇对C6细胞的体外增殖抑制率,筛选出抑制率相对较高且生长状态良好的细胞;应用Hoechest 33342染色透射电镜观察细胞凋亡亚显微结构的改变,采用免疫荧光和Western Blot技术检测与凋亡和自噬相关蛋白的表达水平。结果:卫矛醇对C6胶质瘤细胞增殖有明显的抑制作用,并呈现出良好的浓度-效应相关性,与对照组比较,随着浓度的增加,细胞的增殖抑制率上升(P＜0.01);Hoechst染色结果显示,与对照组相比,共同孵育卫矛醇24 h后的C6细胞出现明显的核固缩现象,证明有大量的细胞出现凋亡;Western Blot结果显示,与对照组相比,促凋亡基因Bax表达上调,抗凋亡基因Bcl-2表达下调。结论:卫矛醇能够抑制C6细胞的增殖,并诱导其凋亡,其作用机制可能与上调Bax、下调Bcl-2有关。     

An examination of directional discontinuities and magnetic polarity changes around interplanetary sector boundaries usingE > 2 keV electrons

Past studies of interplanetary magnetic sector boundaries have been based on the assumption that one can determine the field polarities by comparing the field directions with those of the nominal Parker spiral angles. Previous investigators have found evidence for decreases of B, the magnitude of the magnetic fieldB, and increases of , the angle betweenB and the ecliptic plane, at sector boundaries. Others have argued that the characteristic thickness of sector boundaries exceeds that of tangential discontinuities, making sector boundaries a separate class of structures.We use a simple technique for inferring the polarities of interplanetary magnetic fields based on the assumption thatE > 2 keV electrons are always flowing along the magnetic field away from the Sun. Electron data from the UC Berkeley experiment on the ISEE-3 spacecraft are used to examine periods around several apparent sector boundaries in 1978 and 1979. We compare properties of (a) boundaries with field polarity changes and (b) large-angle ( > 60°) directional discontinuities with no field polarity changes. We find no significant differences between the sector boundaries and the directional discontinuities in terms of associated decreases in B or of values of . These results suggest no significant difference between sector boundaries and directional discontinuities other than the change in field polarities. Within limited statistics we find that about half the polarity changes would not have been identified using a requirement that > 90° and that half of the > 120° discontinuities would have been misidentified as polarity changes.     

Doppler velocity measurements made with a scanning photoelectric magnetograph

We discuss the problems connected with the measurements and evaluation of line-of-sight velocities, obtained with a scanning photoelectric magnetograph using a line-shifter with enhanced sensitivity. We bring arguments for the validity of the results of our photoelectric Doppler velocity recordings. We have found a network of cellularly shaped patterns in the distribution of photo-electrically measured line-of-sight motions, upflowing in the magnetically quiet (blue-shifted) and downflowing in magnetically active (red-shifted) areas of the photosphere, if the mean velocity level is estimated for a sufficiently large measured area. The features of both directions are mutually complementary. We demonstrate the effect of the shift of the reference zero velocity level on the topology of the line-of-sight velocity maps, and the dependence of this level on the size of the area from which it is estimated.     

Dynamical evolution of NEAs: Close encounters, secular perturbations and resonances

We discuss the main mechanisms affecting the dynamical evolution of Near-Earth Asteroids (NEAs) by analyzing the results of three numerical integrations over 1 Myr of the NEA (4179) Toutatis. In the first integration the only perturbing planet is the Earth. So the evolution is dominated by close encounters and looks like a random walk in semimajor axis and a correlated random walk in eccentricity, keeping almost constant the perihelion distance and the Tisserand invariant. In the second integration Jupiter and Saturn are present instead of the Earth, and the 3/1 (mean motion) and v ₆ (secular) resonances substantially change the eccentricity but not the semimajor axis. The third, most realistic, integration including all the three planets together shows a complex interplay of effects, with close encounters switching the orbit between different resonant states and no approximate conservation of the Tisserand invariant. This shows that simplified 3-body or 4-body models cannot be used to predict the typical evolution patterns and time scales of NEAs, and in particular that resonances provide some fast-track dynamical routes from low-eccentricity to very eccentric, planet-crossing orbits.On leave from the Department of Mathematics, University of Pisa, Via Buonarroti 2, 56127 Pisa, Italy, thanks to the G. Colombo fellowships of the European Space Agency.     

Sm-Nd ISOTOPIC AGE OF LAMPROPHYRES IN THE GEZHEN GOLD-BEARING SHEAR ZONE ON HAINAN ISLAND AND ITS GEOLOGICAL IMPLICATIONS

Sm-Nd isotopic compositions of eight lamprophyre samples, which come from the Gezhen gold-bearing shear zone on western Hainan Island, are measured. The Sm-Nd isochron age is 495.98±13.14 Ma, (143Nd/144Nd) 0=0.512094, εNd(t) ranges from +1.80 to +2.00 and TDM from 982 Ma to 1196 Ma (average: 1060 Ma). The authors point out that the whole-rock Sm-Nd isochron age (495.98 ± 13.14 Ma) really represents the petrogenetic age of lamprophyre and the time of magmatism during subsequent subduction.     

资源环境与社会经济协调发展探析

文章首先回顾了资源环境与社会经济发展的理论，提出资源环境与社会经济协调发展内涵：一方面，要在资源环境承载力范围内发展社会经济，追求社会经济发展的最大化，另一方面，环境承载力是动态的，要依靠社会经济发展不断提高，这两个方面是相互作用、相互制约的。在此基础上，详细论述了资源环境与社会经济协调发展的内容,并从社会经济发展、资源环境管理等角度探讨了资源环境与社会经济协调发展的政策调控，通过建立节约型国民经济体系、深化资源环境管理，实现区域一体化，以保证资源环境与社会经济协调发展的实现。     

An oases dynamics model and its application in the Manas oasis

This study applies theories of systems and system dynamics to ecological economic systems in the oasis environment, with the intention of finding the basic characteristics of the oasis environment and its feedback structures. This study explores the inner mechanisms of economic development in the oasis environment and its relationship to policy variables. This model is applied to economic development in the Manas oasis of the Xinjiang Uygur Autonomous Region of China. System dynamics method starts from studying feedback structure within the system study and then searches for the best solution through identifying the right "policy point" and through model simulation in the computer. It embodies the cream of "systems cybernetics theory". This study is justified because the nature of the oasis system and the simulation results are scientifically sound and practically feasible.