Isolation and pharmacological activities of bromophenols from Rhodomela confervoides

Four bromophenols were isolated from the extract of marine red alga,Rhodomela confervoides by column chromatography and HPLC methods. By means of spectroscopic methods inclding IR, MS, 1D, and 2D-NMR techniques, their structures were elucidated as (1) 3-bromo-4,5-dihydroxy benzoic acid methyl ester; (2) bis (2,3-dibromo-4,5-dihydroxybenzyl) ether; (3) 3,4-dibromo-5-(methoxymethyl)-1,2-benzenediol and (4) 3-bromo-4,5-dihydroxy-benzaldehyde. Compound 1 was first isolated from the algae in nature, and 1, 4 were found to have selective cytotoxic activities against KB, Bel 7402 and A549 cells, 2 showed powerful antibacterial activities againstStaphylococcus aurens andPseudomonas aeruginosa. Supported by National “863” Program (No. 2004AA625030, 2001AA620503), Quingdao marine sciences project (No. 04-2-NN-26) and Key Knowledge Innovative Project of the Chinese Academy of Sciences (KZCX3-SW-215).     

Oxygen isotopic compositions and origins of calcium‐aluminum‐rich inclusions and chondrules

Abstract— Primary minerals in calcium‐aluminum‐rich inclusions (CAIs), Al‐rich and ferromagnesian chondrules in each chondrite group have δ¹⁸O values that typically range from ?50 to +5%0. Neglecting effects due to minor mass fractionations, the oxygen isotopic data for each chondrite group and for micrometeorites define lines on the three‐isotope plot with slopes of 1.01 ± 0.06 and intercepts of ?2 ± 1. This suggests that the same kind of nebular process produced the ¹⁶O variations among chondrules and CAIs in all groups. Chemical and isotopic properties of some CAIs and chondrules strongly suggest that they formed from solar nebula condensates. This is incompatible with the existing two‐component model for oxygen isotopes in which chondrules and CAIs were derived from heated and melted ¹⁶O‐rich presolar dust that exchanged oxygen with ¹⁶O‐poor nebular gas. Some FUN CAIs (inclusions with isotope anomalies due to fractionation and unknown nuclear effects) have chemical and isotopic compositions indicating they are evaporative residues of presolar material, which is incompatible with ¹⁶O fractionation during mass‐independent gas phase reactions in the solar nebula. There is only one plausible reason why solar nebula condensates and evaporative residues of presolar materials are both enriched in ¹⁶O. Condensation must have occurred in a nebular region where the oxygen was largely derived from evaporated ¹⁶O‐rich dust. A simple model suggests that dust was enriched (or gas was depleted) relative to cosmic proportions by factors of ～10 to >50 prior to condensation for most CAIs and factors of 1–5 for chondrule precursor material. We infer that dust‐gas fractionation prior to evaporation and condensation was more important in establishing the oxygen isotopic composition of CAIs and chondrules than any subsequent exchange with nebular gases. Dust‐gas fractionation may have occurred near the inner edge of the disk where nebular gases accreted into the protosun and Shu and colleagues suggest that CAIs formed.     

用遗传算法解算病态方程

对应用遗传算法解决病态方程问题进行了探讨。利用拟合法而不是通过法方程求解参数，从而避免了法方程系数求逆，使病态方程的解答有了较好的结果。通过模拟计算并和其他方法进行比较，证明该方法是可行的和有效的。     

同震阶变异常的特征与机制分析

本文对徐州地震台JB—72水平摆倾斜仪1988年11月至1989年5月间所记录到的24次同震阶变进行了深入分析,认为:a.造成同震阶变的原因是多方面的,而反应了地球应变场准静态调整的同震阶变才是有价值的价变异常;b.多观测手段的地震台站,同震阶变应该在不止一台仪器上得到响应。     

关于建设菏泽数字国土工程的初步探讨

菏泽数字国土工程主要包括国土资源政务管理信息、土地管理信息、地质矿产资源信息、国土测绘管理信息和国土资源法规监察信息。3S术是其工程中空间数据获取和管理的技术基础。在工程建设中应首先科学编制建设规划。通过规划确定方针，提出目标，明确任务，有序地开展建设。     

介质横向不均匀对震后地表位移场的影响

利用三维有限元模拟两层地球模型(包括弹性层和粘弹性层)介质的横向不均匀和断层错动的复杂性对震后地表位移场的影响，其数值结果包括弹性解和粘弹性解。结果表明，震后位移场的分布特征不仅与粘弹性层的流变特性有关，还与弹性层介质的剪切模量以及断层的同震错动有关。     

Study on application of polyenzyme method to offal of Harengula zunasi

The new polyenzyme method for making gravy fromHarengula zunasi offal involves protein enzymolysis with flavorase after proper alkaline and neutral protease levels were established by orthogonal trials to select the best hydrolytic conditions for processing offal with alkaline and neutral protease. The conditions for the polyenzyme method were pH of 7.0, temperature of 50°C, alkaline and neutral protease concentration of 1.5% respectively, hydrolysis time of 120 min, and flavorase concentration of 2.0%, for 60 min. The new gravy-making technology yields a nutritious and delicious gravy containing 40.3% of total essential amino acids, with delicious amino acids Glu, Asp, Gly, Ala, Pro and Ser comprising 49.5%, total and amino nitrogen being respectively 1.9 and 1.1 g/100 g (amino acid nitrogen being 61.0% of total nitrogen), The polyenzyme method was used to make 14.8% protein gravy fromHarengula zunasi offal. In addition, inorganic elements, the phosphorus content is the highest. This project was aided financially by the Guangdong Science and Technology Office (No. 2KM06002S).     

山东省1∶20万水文地质数据库建设的主要内容及开发应用设想

山东省1∶20万空间数据库结合山东省区域水文地质特点,共建立了27个图层,完成12个图幅的建库工作。通过该项工作,为今后进行空间分析和应用研究打下了基础,并为数字水文地质图空间数据库的建设积累了丰富的经验。     

长江三峡工程地壳形变监测网络

长江三峡工程地壳形变监测网络，采用了当今高精度GPS、INSAR空间大地测量技术，并与精密水准测量，精密重力测量，精密激光测距和峒体连续形变监测等技术相结合，构成一个空间上点、线、面结合，时间上长、中、短兼顾的高精度，高时空分辨率的地壳形变监测网络。该网络既可获取三峡库区特别是库首区区域形变场和区域应变场的动态变化，监测库区主要断层活动，为水库诱发地震预测及研究服务，又可用于气象、滑坡地质灾害监测等，该监测网络于1997年底开始建设，2001年6月建成，到目前为止，已获得大量宝贵的观测资料，必将产生显著的经济效益和社会效益。