补肾生血方对肾性贫血大鼠EPO水平及EPOR mRNA的影响

目的：研究补肾生血方对肾性贫血大鼠促红细胞生成素（EPO）及EPOR mRNA水平的影响。方法：Wistar大鼠50只,分为对照组、模型组、中药组、EPO组、中药+EPO组,每组各10只,对除对照组外的其余组大鼠通过腺嘌呤灌胃制备肾性贫血大鼠模型,分别给予相应药物进行干预。分别于给药第2、8周观察血常规指标（Hb、RBC、HCT）、肾功能指标（BUN、Scr）的水平及EPO浓度,给药8周后处死大鼠,提取骨髓单个核细胞,测定EPOR mRNA表达量的变化。结果：与治疗2周相比,治疗8周中药组、EPO组、中药+EPO组大鼠的BUN、Scr显著降低,Hb、RBC、HCT、EPO水平及EPOR mRNA表达量显著上升,差异均有统计学意义（P＜0.05）。结论：补肾生血方具有改善肾性贫血模型大鼠肾功能、肾性贫血状况,其机制可能与提高骨髓有核细胞EPOR mRNA表达量,减轻毒素对EPOR的抑制,加强对内源性EPO反应性有关。     

Classification of stellar spectra with SVM based on within-class scatter and between-class scatter

Support Vector Machine (SVM) is a popular data mining technique, and it has been widely applied in astronomical tasks, especially in stellar spectra classification. Since SVM doesn’t take the data distribution into consideration, and therefore, its classification efficiencies can’t be greatly improved. Meanwhile, SVM ignores the internal information of the training dataset, such as the within-class structure and between-class structure. In view of this, we propose a new classification algorithm-SVM based on Within-Class Scatter and Between-Class Scatter (WBS-SVM) in this paper. WBS-SVM tries to find an optimal hyperplane to separate two classes. The difference is that it incorporates minimum within-class scatter and maximum between-class scatter in Linear Discriminant Analysis (LDA) into SVM. These two scatters represent the distributions of the training dataset, and the optimization of WBS-SVM ensures the samples in the same class are as close as possible and the samples in different classes are as far as possible. Experiments on the K-, F-, G-type stellar spectra from Sloan Digital Sky Survey (SDSS), Data Release 8 show that our proposed WBS-SVM can greatly improve the classification accuracies.     

吉林大椅子山火山年代学、地球化学特征及其排气量的估算

利用铀系组分法测得龙岗大椅子山火山喷发时间为距今71±9ka,属于晚更新世。各类喷发物的岩石化学、地球化学特征表明 ,它们形成于同一岩浆源。根据岩石学方法 ,结合Thordarson(1996)等人的排气模型 ,估算此次喷发向大气层输送的HCl、HF总量分别为7.36Mt和5.21Mt。     

花海拗陷的热演化和生烃期的磷灰石裂变径迹证据

利用裂变径迹分析方法测量了取自花海拗陷的钻井磷灰石样品的裂变径迹年龄和长度。结果表明,随井深增加年龄减小,平均径迹长度亦变短。取自白垩纪地层的磷灰石样品的裂变径迹年龄都比地层年龄年轻得多,表明沉积后曾长时间处于磷灰石裂变径迹退火带中,沉积前的径迹记录已部分消失,古地温高于今地温。利用蒙特卡罗随机取样的热史模拟方法对裂变径迹数据进行了分析,结果表明白垩纪地层沉积后曾经历过超过110 ℃的加热,达到最高古地温的地质时代是早白垩世晚期—晚白垩世末,为主要生烃期。新生代以来盆地变冷,生油岩的成熟度主要受古地温控制     

峪耳崖金矿的成矿时代裂变径迹研究

通过峪耳崖金矿含矿岩体中的锆石、磷灰石裂变径迹分析，揭示了自中生代燕山期以来峪耳崖地区经历了频繁、多期次的热液活动，且与峪耳崖金矿的形成密切相关。锆石、磷灰石的裂变径迹年龄显示，金矿成矿时代主要为115～200Ma，成矿下限为82Ma。其中，115～190Ma是主要的成矿时期。成矿流体作用遍及整个岩体；流体的运移受到构造制约，具有NE—SW延伸的趋势；成矿流体具深部来源以及在地表水的参与下成矿。峪耳崖金矿的形成，与当时整个中国东部的动力学背景有关。     

池塘养殖脊尾白虾(Exopalaemon carinicauda)感染血卵涡鞭虫的研究

通过现场取样、显微镜检、细菌培养、组织病理、电镜观察以及PCR检测等研究手段,对2008年9月浙江省舟山市普陀区某梭子蟹养殖塘混养的脊尾白虾"白浊病"进行了系统的病原学研究。结果表明,病虾体色发白,反应迟钝,血淋巴液呈浊白色,严重患病白虾血淋巴中的血细胞几乎没有或者极少,代之以大量与血细胞形似的寄生虫;组织病理切片及电镜观察发现,病虾心脏、肝胰腺、肌肉、鳃部等组织寄生有大量单细胞寄生虫,该寄生虫虫体形态特征、显微结构及宿主临床症状与本实验室之前研究报道的感染三疣梭子蟹和锯缘青蟹的血卵涡鞭虫类似;采用已建立的针对血卵涡鞭虫ITS1基因的引物对"白浊病"病虾的血淋巴样品进行PCR检测,可扩增出585bp左右的特异条带。综合以上研究结果,确定该寄生虫为血卵涡鞭虫(Hematodinium sp.)。有关脊尾白虾感染该寄生虫的报道在国内外尚属首次。     

现代黄河三角洲沉积层压实下沉的计算分析

1855年以来形成的厚度为15 m的现代黄河三角洲分流叶瓣在遭废弃后的最近30 a内的沉积压实幅度为2.28～3.87 m,年平均压实量达0.1 m,其中黏土质粉砂被压实了25.8%,粉砂沉积地层被压实了15.2%,黏土质粉砂的沉积压实量是粉砂沉积压实量的1.7倍,在此期间基本上完成了三角洲压实下沉过程。下伏沉积地层的压缩量有限,不同沉积年代的沉积压实下沉量相差小,如厚度为20～30 m的沉积压实量仅有0.2～0.28 m,其中黏土质粉砂被压实了0.91%,粉砂被压实了1.19%,沉积地层平均被压实了1%。无论是黏土质粉砂还是粉砂,孔隙度与沉积地层深度呈负指数函数关系,黏粒含量愈高,孔隙水则愈难以排出,覆盖在下伏沉积地层上面的表层沉积物对压实下沉贡献愈大。     

Faithful quantum secure direct communication protocol against collective noise

An improved quantum secure direct communication (QSDC) protocol is proposed in this paper. Blocks of entangled photon pairs are transmitted in two steps in which secret messages are transmitted directly. The single logical qubits and unitary operations under decoherence free subspaces are presented and the generalized Bell states are constructed which are immune to the collective noise. Two steps of qubit transmission are used in this protocol to guarantee the security of communication. The security of the protocol against various attacks are discussed.     

Stable 85Rb micro vapour cells: fabrication based on anodic bonding and application in chip-scale atomic clocks

We describe the microfabrication of ⁸⁵Rb vapour cells using a glass-silicon anodic bonding technique and in situ chemical reaction between rubidium chloride and barium azide to produce Rb. Under controlled conditions, the pure metallic Rb drops and buffer gases were obtained in the cells with a few mm³ internal volumes during the cell sealing process. At an ambient temperature of 90 ℃ the optical absorption resonance of ⁸⁵Rb D1 transition with proper broadening and the corresponding coherent population trapping (CPT) resonance, with a signal contrast of 1.5% and linewidth of about 1.7 kHz, have been detected. The sealing quality and the stability of the cells have also been demonstrated experimentally by using the helium leaking detection and the after-9-month optoelectronics measurement which shows a similar CPT signal as its original status. In addition, the physics package of chip-scale atomic clock (CSAC) based on the cell was realized. The measured frequency stability of the physics package can reach to 2.1×10^-10 at one second when the cell was heated to 100 ℃ which proved that the cell has the quality to be used in portable and battery-operated devices.     

广东流沙湾4个测站2个周日潮流观测的准调和分析

采用短期资料的潮流准调和分析方法,对水深为4.4～17.0 m的流沙湾4个测站2个周日潮流观测获得的表、中、底层的潮流资料进行了分析,分别计算了4个测站O1、K1、M2、S2、M4、MS4共6个主要分潮的潮流调和常数,并给出了各观测站位在各层的潮流椭圆要素.计算结果表明：流沙湾主要为日潮流海区,其中湾外为规则日潮流,湾内为不规则日潮流;湾外主要分潮流的北分量一般大于东分量,而湾内主要分潮流的北分量一般小于东分量.观测期间余流的流向主要呈西北向,最大余流流速出现在湾内地形突然收窄处,且在湾内中层余流流速要大于表、底层余流流速.整个海区潮流的可能最大流速表层在57～107 cm/s之间,中层在53～106 cm/s之间,底层在34～98 cm/s之间.流沙湾湾外潮流主要为顺时针的旋转流运动,湾内为带有旋转流的往复流运动.