Protective effect of topically applied polypeptide from Chlamys farreri against ultraviolet radiation-induced chronic skin damage in guinea pig

Polypeptide fromChlamys farreri (PCF), a topical polypeptide isolated fromChlamys farreri, was used in this experiment aimed to investigate the photoprotective effect of PCF against chronic skin damage induced by ultraviolet A (UVA) and ultraviolet B (UVB) radiation. The chronic ultraviolet-irradiated guinea pig model was established, and visible changes in the skin including wrinkling, sagging and erythema were observed. Malondialdehyde (MDA) and antioxidant enzymes including superoxide dismutase (SOD) and glutathione peroxidase (GSH-px) in the dorsal skin were determined using biochemical methods. The results showed: (1) PCF (5 % and 20%) could greatly protect the dorsal skin of guinea pig against wrinkling, sagging and erythema induced by UV radiation in a concentration-dependent manner. (2) PCF could reduce MDA formation in the dorsal skin caused by UV irradiation, while increasing the activities of SOD and GSH-px. (3) The differences among the PCF groups and UV model group were significant (P<0.05,P<0.01). These results indicated that topical application, of PCF provided broad solar UV spectrum photoprotection; and that the antioxidant property of PCF might play a role in photoprotection. Project No. 39970638 supported by the NSFC, and the Science and Technology Bureau of Qingdao (No. 2001-28-50).     

ANALYSIS OF DRIVING FORCES ON THE CHANGE OF HISTORICAL FARMLAND USE IN SHANDONG PROVINCE DURING THE QING DYNASTY (1644-1911)

1INTRODUCTIONTheIGBP-IHDP(InternationalGeosphere-BiosphereProgramme,andInternationalHumanDimensionPro-gramme)jointproject—LUCC(landuse/coverchange)isaninterdisciplinaryprogramdesignedtoimprovetheunderstandingofthedynamicsofland-useandland-coverchangeasinputstoandconsequencesofglobalenvironmentalchangeandsustainabledevelopment(CHARLOTTE,2002).Inparticularthedifferentbio-geochemicalmodeling(e.g.theglobalcarboncycle)ac-tivitiesandcomparativestudies,suchasthoseconduct-edbyIGBP-G…     

小行星(360)Carlova自转参数的测定

小行星自转参数的资料不仅可以为小行星碰撞演化提供数据,还可以为太阳系的演化研究提供依据．利用云南天文台1米望远镜对主带碳类小行星(360)Carlova进行了新的CCD测光观测,结合前人的测光资料,利用Epoch-方法对(360)的自转参数进行了反演计算,得到该小行星自转的恒星周期为0．25780417±0．00000003天,自转轴的黄道坐标为(95°±3,°40°±1°)．新的结果与前人的结果相比较为一致,其精度稍高于以前的估算结果．     

酶解法提取鱼油的工艺参数优化

利用蛋白酶酶解法从黄鳍金枪鱼（Thunnus albacares）加工的下脚料——鱼头中提取鱼油。以鱼油提取率和感官特征为指标，通过正交优化实验设计，获得了胰蛋白酶提取鱼油的最佳酶解工艺参数：酶解温度45℃，酶添加量1．5％．料液质量比1：1，酶解时间4h，酶解pH8。在该条件下．鱼油的提取率为4．34％，理化指标除过氧化值外均达到SC／T3502-2000的粗鱼油二级标准。多不饱和脂肪酸总含量高达38．47％,其中DHA和EPA的含量分别为23．63％和4．84％。     

胶东“玲珑-焦家式”金矿资源潜力与找矿

“玲珑焦家式”金矿的成岩成矿,从新太古代至中生代存在着继承性的成因关系,成矿具有长期性、多源性特点,但中生代燕山早期岩浆活动是主导成矿因素。区域化探成果显示胶东金矿直接矿源岩———郭家岭花岗岩金的丰度比原始矿源岩———早前寒武纪变质沉积岩系及侵入岩系金的丰度低1/2。郭家岭花岗岩面积在2 km2以上岩体定量估计金亏损总量与胶东金矿总量预测的资源量相当,从一个侧面展现了胶东金矿资源的潜力。望儿山金矿的找矿实践展示,焦家式金矿在1 000 m以下尚有巨大潜力,整个胶东金矿产区在3 000 m以上的资源潜力应在5000 t以上。     

差分法周跳探测与修复方法改进

在目前常用的周跳探测与修复方法基础上 ,提出了首先将观测资料按照观测历元不连续分成若干小弧段 ,然后利用差分法进行周跳探测 ,根据差分后周跳放大的特性判断周跳和野值 ,并确定其位置利用宽带组合和电离层组合的方法解算周跳大小。通过实例验证了其有效性。     

Application of Grain Size Analysis to Study Sedimentary Environment of Sand Dune in the Vicinity of Tumen River

The dunes in estuary of Tumen River in China lie to the area between the Jiushaping and Fangchuan in the left bank of Tumen River (Fig.1). The dis-tance is about 15～20 km between the dunes and the coast. It ranges from China to D. P. R. Korea and Russia. The range of the height of dunes is about 15～20 m and the width is 100～200 m. By the re-connaissance, we protracted 9 section planes of the dunes and collected 40 sand samples of the dunes, and identified the sedimentary environment …     

应用GPS观测青藏高原东北缘应力场变化

采用各向同性弹性地球模型推导了地面位移场速率与地壳内任意点应力场变化的边界积分关系,同时利用青藏高原东北缘1999～2001年观测的GPS资料对观测区地壳深度为5 km和25 km的主应力和最大剪应力进行了计算分析.结果表明,青藏高原东北缘的主应力变化主要集中在祁连山断裂、海原断裂等,在1920～1954年间历史上发生过多次震级为7.0～8.5级强震的断裂附近,并具有主应力变化沿断层走向分布、最大剪应力沿断层走向交替变化等特征.     

新近对耀变体(Blazar)的X射线观测

本文综述了ASCA ,RXTE ,BeppoSAX和XMM -NEWTON对TeV耀变体 (Blazar)X射线研究的最新进展。主要集中在X射线资料的时间和光谱分析的最重要的方面 ,包括功率谱密度 ,结构函数 ,带间时间延迟 ,同步峰值能量的漂移和谱演化。对这些新结果的物理意义也进行了简要讨论。