Optimal Design for Main Dimensions of a 75000t Floating Production and Storage Vessel

The basis, process and results of the demonstration of the main dimensions of a 75000t floating production and storage vessel are discussed in this paper. A simple but reliable orthogonal design method is applied in the main dimension optimization. The ideas of gradual approximation and feedback from various aspects are put into effect. During the demonstration, in order to make the model tally with the actual situation, the draft design is closely related to the computational analysis, so that the demonstration model can be verified at any time; the handling of the overall system is closely related to the research of each item, which is beneficial not only to the mastery of various regularities, but also to the balance of decisions. Finally, according to the computational results and the regularities obtained from analysis, the main dimensions are determined.     

地学在加拿大近海渔业生产和管理中的作用

地学在近海渔业管理中的应用虽是个刚刚兴起的研究领域，但已向人们展示了它令人振奋的成果。通过分析地学成果的获取、表达及地球物理技术的进展情况，介绍了加拿大地学专家如何成功地将地学成果应用于指导近海渔业捕捞，以及如何利用地学知识评价不同捕捞器材对环境的影响。     

桶形基础平台三维有限元稳定性分析

以我国第一座桶形基础采油平台工程实例为原型，采用三维有限元计算方法对桶形基础稳定性分析。平台在波浪、风等荷载作用下，其稳定性不仅与平台的整体结构有关，而且与桶形基础及其周围土体相互作用相关。在计算中，利用薄层摩擦单元模拟土与结构间的相互作用，取得了很好的效果。分析结果表明桶形基础采油平台在设计条件下运行是较为稳定的。     

Fatigue Behavior of Plain Concrete Under Biaxial Compression: Experiments and Theoretical Model

The effects of different lateral confinement stress on the fatigue behavior of and cumulative damage to plain concrete are investigated experimentally. Eighty 100 mm x 100 mm x 100 mm specimens of ordinary strength concrete are tested under constant- or variable-amplitude fatigue loading and lateral confinement pressure in two orthogonal directions. A fatigue equation is developed by modifying the classical Aas-Jakobsen S-N equation for taking into account the effect of the confined stress on fatigue strength of plain concrete. The results of variable-amplitude fatigue tests indicate that the linear damage theory proposed by Palmgren and Miner is unreasonable in the biaxial stress state. A nonlinear cumulative damage model that could model the effects of the magnitude and sequence of variable-amplitude fatigue loading and lateral confinement pressure is proposed on the basis of the evolution laws of the residual strains in the longitudinal direction during fatigue tests. The residual fatigue life predic     

台湾海峡隧道工程的若干工程地质问题与选线方案探讨

对台湾海峡的地质状况了进行了分析，作者认为，台湾海峡的工程地质条件复杂，地震、活动断裂、岩土体稳定性、海底底床活动性等是隧道工程将遇到的主要工程地质问题。隧道的线路选择应进行全面、深入的技术、经济比较。平潭至新竹和厦门经澎湖至嘉义海滨是两个可选的隧道线路方案。     

Cyclone formation and development in the Antarctic Prydz Bay

Using meteorological data of field observation in 1990 - 2000, especially polar orbit high-resolution NOAA satellite cloud maps received from the Antarctic expedition vessel since 1997, the formation and development of the Prydz Bay cyclone are studied in this paper. Some new viewpoints are suggested such as: when surround-polar cyclone enters the Prydz Bay, it can also intensify and develop in summer; cyclone can also develop in the easterlies in this bay. These view points revise old uncom-plete view point that the Prydz Bay is a burial ground of cyclone, and also further consummate formation-development theory of surround-cyclone in the Antarctic westerlies and cyclone in the Antarctic easterlies. In this paper, the mechanism of ice-air-sea interaction in the Prydz Bay is studied, and the physical process of cyclone formation-development is explained. By use of wholly dynamic transportation method, an energy exchange case of a cyclone, which explosively developed after entering the Prydz Bay, is calcu     

东亚冬夏季风对热带印度洋秋季海温异常的响应

利用多年的Reynolds月平均海表温度资料和NCEP/NCAR全球大气再分析资料,分析了热带印度洋秋季海表温度距平(SSTA)与后期东亚冬夏季风强度变化的关系。结果表明,热带印度洋秋季SSTA的主要模态是全区一致(USB)型和偶极子(IOD)型,USB型模态主要代表热带印度洋秋季SSTA的长期变化趋势,而IOD型模态主要反映热带印度洋秋季SSTA的年际变化。热带印度洋秋季海温气候变率中既存在着明显的ENSO信号,也有独立于ENSO的变率特征,独立于ENSO的热带印度洋秋季SSTA变化的主要模态仍是USB型和IOD型。前期秋季USB模态与东亚冬季风及东亚副热带夏季风之间为负相关关系;与前期正(负)IOD模态相对应,南海夏季风强度偏弱(强),而东亚副热带夏季风强度偏强(弱)。USB型和IOD型模态对后期东亚冬、夏季风强度变化的影响是独立于ENSO的,但ENSO起到了调节二者相关显著程度的作用。     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

Discussion on Coastal Erosion Near Xizhuang, Penglai, China

-In this work, on the basis of the characteristics of coastal erosion near Xizhuang (Penglai, Shandong, China) and the in-situ measured data and theoretical calculation, the causes of coastal erosion there are obtained: (1) natural erosion, (2) beach sand borrowing, and (3) sand borrowing at the Dengzhou shoal near Xizhuang, which results in the loss of the function of the wave force resistance of the shoal. Since the wave energy is increased, the longshore sediment transport rate is increased. Coastal erosions are more and more serious. A scientific basis to reduced the calamity of coastal erosion in local area is presented. Some experiences are accumulated for studying coastal erosion.     

东海西北部水团分析及与渔场的关系

作者用聚类分析法划分浅海水团,目的在于克服大洋水团分析法进行分析所遇到的一些困难,它在根据不同海区特点确定临界值与检验值时有较大的灵活性。本文讨论了浅海变性水团与中心渔场的关系。结果表明,东海底层冷水、东海表层水和大陆沿岸水对渔业生产有重要影响。