1975-2015年鄂尔多斯市沙漠化的时空演变过程

鄂尔多斯市地处温带草原向荒漠草原过渡的半干旱区,是中国沙漠化问题较为严重的区域之一,其土地沙漠化发展和逆转过程及影响因素在北方农牧交错带具有代表性。以7期Landsat卫星遥感数据为信息源提取沙漠化土地类型及程度的时空格局信息,分析了该地区自1975年以来的土地沙漠化过程,并结合气象及社会经济数据采用主成分分析法对驱动因子进行定量分析。结果表明：在脆弱生态环境背景下,鄂尔多斯市土地沙漠化受人口数量增加、过垦及过牧等人为因素的严重影响。不同时段土地沙漠化发展的方向与驱动力都有所不同,1975-2000年是土地沙漠化的急剧发展期,驱动力以人为因素为主导,自然因素为基础;2000-2015年是土地沙漠化的逆转期,驱动力以自然因素为主,人为因素为辅。     

Integration of InVEST-habitat quality model with landscape pattern indexes to assess mountain plant biodiversity change: A case study of Bailongjiang watershed in Gansu Province

Journal of Geographical Sciences - Mountains in western China, hosted rich biodiversity and millions of people and inhabitant with vital ecosystem services, had experienced the most serious...     

Divergent Perspectives on Water Security: Bridging the Policy Debate

Environmental policy discussion is replete with references to water security, food security, ecosystem health, community resilience, sustainable development, and sustainable urbanism. These terms are, by their very nature, ambiguous and difficult to define; they allow room, however, for a variety of actors to conceptualize water, food, ecological, economic, and urban problems in ways that allow them to move forward on contentious issues. This article focuses on the idea of water security and asks how it is conceptualized and used for regional policy debate in western Canada. We asked fifty-eight water stakeholders from the Saskatchewan River Basin to define water security, identify major barriers to security, and prioritize water problems. Responses showed there are myriad ways to think about water security, ranging from narrow conceptualizations, such as reliability, quality, and quantity, to broader sustainability perspectives about the nature of resource development and its social and economic consequences. The human dimensions of water security (governance, land use, and competing demands) were assigned higher priority than its biophysical aspects (flooding, droughts, and climate change). Framing water security to emphasize the human capacity to manage uncertain and rapid biophysical and societal change offers the opportunity to unite actors who otherwise would be separated by core environmental values, definitions of water security, provincial context (Alberta vs. Saskatchewan), and occupation.     

Restructuring the export-oriented industrialization in the Pearl River Delta, China: Institutional evolution and emerging tension

The rise of the Pearl River Delta (PRD) as a promising workshop of the “world factory” in China has attributed to the export-oriented industrialization driven by foreign direct investment, particularly Overseas Chinese investment from Hong Kong and Taiwan initiated in the late 1970s. The export-oriented industrialization has embedded in the flexible institutions favourable for foreign investors and local authorities, via the salient entry mode, i.e. processing with supplied materials (lailiaojiagong). Since the mid-2000s, the export-oriented industrialization has undergone dramatic restructuring to cope with the changing business environment at global, national and regional and firm levels. Drawing upon the evolutionary and institutional perspectives in geographical political economy approach, this study argues that the prevailed institutions conducive for the export-oriented processing have evolved into institutional inertia and territorial embeddedness as obstacles for the on-going restructuring, particularly the market reorientation from export to domestic sale. Moreover, difficulties of restructuring through the state-designated relocation have been heightened by the resistance from below and emerging state-firm tension. The institutional evolution of the export-oriented industrialization in the PRD has enriched the literature on industrial restructuring in the context of dynamic global-local interactions, but also provided fundamental implications for formulating well-coordinated restructuring strategies among various institutions and concerned actors.     

Barchans of Minqin: Morphometry

The barchans on the border of Minqin oasis, China, were surveyed. Our data reconfirmed that the height of slipface is proportional to the width of horns and the baseline can be roughly described by parts of an ellipse and a parabola. We attempted to study dune geomorphology using the theory of differential geometry. The geometrical characteristics of the brink can be quantitatively determined by its curvature and torsion.     

Dehydration melting of solid amphibolite at 2.0 GPa: Effects of time and temperature

The dehydration melting of the natural rock at high pressure is important to investigating the magma formation in the earth’s interior. Since the 1970s, a lot of geological scientists have paid more atten- tion to the dehydration melting of the natural rock[1―5]. Previous experiments of dehydration melting and observations of fieldwork argued that the dehy- dration melting of the rock was probably the most important fashion for the melting of the lower crust rock[6―12]. The genesis of most …     

我国断层气测量在地震科学研究中的应用现状

氢气被认为是反应断裂活动最灵敏的地球化学组分之一。研究影响断裂带氢浓度动态变化的主要因素,是科学分析断裂带氢与构造活动关系的基础工作。本文基于河南内乡马山口断层气氢气浓度与辅助测项的连续观测资料,重点分析了氢浓度变化与地温、气温、气压的相关关系,确定了主要影响因素。结果表明,氢气浓度日变化极值介于气温和地温之间,极值点靠近地温一侧。使用逐步回归方法分析进一步证明,地温、温度对氢气浓度均有影响,但地温影响更显著,气压影响不显著。总体来讲,氢浓度会受到地温和气温的双重影响,但与地温关系更为密切。     

基于网络药理学和分子对接技术探究柯里拉京治疗卵巢癌的关键靶点及分子机制

目的：采用网络药理学和分子对接技术相结合的方法探究柯里拉京（Cor）治疗卵巢癌的关键作用靶点和分子机制。方法：利用PharmMapper、TargetNet及Swiss Target Prediction在线工具预测Cor的作用靶点,通过OMIM、TTD、CTD、DisGenet、PharmGKB及MalaCards数据库获取卵巢癌相关的疾病靶点,并将药物靶点与疾病靶点取交集得到Cor治疗卵巢癌的预测靶点。借助STRING数据库、Cytoscape 软件构建蛋白质-蛋白质相互作用（PPI）网络,并采用CentiScape插件筛选出PPI网络中的核心靶点。运用GEPIA和Kaplan-Meier Plotter在线平台分别对这些核心靶点进行基因表达差异分析和生存分析,以明确Cor治疗卵巢癌的关键靶点。利用DAVID数据库进行基因本体（GO）功能及京都基因与基因组百科全书（KEGG）通路富集分析。运用Autodock Vina软件进行正向分子对接,预测关键靶点和Cor之间的结合活性。结果：Cor治疗卵巢癌的预测作用靶点共24个,其中RAC-α丝氨酸/苏氨酸蛋白激酶(AKT1)、表皮生长因子受体(EGFR)、雌激素受体1(ESR1)、原癌基因酪氨酸蛋白激酶(SRC)是Cor治疗卵巢癌的关键靶点,主要涉及血管内皮生长因子(VEGF)信号通路、缺氧诱导因子-1(HIF-1)信号通路及叉头样转录因子(FoxO)信号通路,可能通过调控细胞凋亡、细胞增殖、血管内皮细胞迁移等生物过程而发挥治疗卵巢癌的作用。分子对接结果显示,Cor与预测靶点之间具有较好的亲和力,表明通过网络药理学预测作用靶点的方法具有良好的可靠性。结论：Cor是通过多靶点、多通路的协同作用来干预多个生物过程,从而发挥其抗卵巢癌疗效,为进一步研究其治疗卵巢癌的分子机制提供了新的线索。     

考虑海平面上升影响的极值水位计算

本研究基于非平稳序列极值理论,定量分析极端水位事件年超越概率受海平面上升的影响;以工程设计使用年限内极端水位发生概率作为控制条件,构建考虑海平面上升的极值水位计算方法;结合平均海平面的长期变化过程,推算海平面上升下的极值水位。基于全球10个验潮站历史水位观测资料,验证历史平均海平面长期变化与高、低水位耿贝尔分布位置参数变化的一致性以及构建方法的合理性。结合政府间气候变化专门委员会对海平面上升的预测,推算和对比分析不同海平面上升情景下的极值水位,并评估相应极值水位在当前极值分布中的重现期。