Protective effects of C-phycocyanin on alcohol-induced acute liver injury in mice

Excessive alcohol consumption leads to liver disease. Extensive evidence suggests that C-phycocyanin (C-PC), a chromophore phycocyanobilin derived from Spirulina platensis, exerts protective effects against chemical-induced organ damage. In this study, we investigated whether C-PC could protect against ethanol-induced acute liver injury. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), total cholesterol (CHOL), low-density lipoprotein (LDL), liver homogenate malondialdehyde (MDA), superoxide dismutase (SOD) content were measured, and pathological examination of liver sections were examined. C-PC showed obvious inhibitory effects on serum ALT, AST, TG, CHOL, LDL and MDA, and SOD content significantly increased in the liver. The structure of hepatic lobules was clear, liver sinus returned to normal, and liver cell cords were arranged in neat rows. Cloudiness, swelling, inflammatory cell infiltration and spotty necrosis of liver cells were significantly reduced. Therefore, C-PC can significantly protect against ethanol-induced acute liver injury.     

A micro–macro investigation of the capillary strengthening effect in wet granular materials

Wet granular materials are three-dimensionally simulated by the discrete element method with water bridges incorporated between particles. The water bridges are simplified as toroidal shapes, and the matric suction is constantly maintained in the material. A comparison with experimental tests in the literature indicates that the toroidal shape approximation may be one of the best choices with high practicability and decent accuracy. Mechanical behaviours of wet granular materials are studied by triaxial tests. Effects of particle size distributions and void ratios are investigated systematically in this study. The hydraulic limit of the pendular state is also discussed. It gives the capillary cohesion function which is not only determined by the degree of saturation but also positively correlated to relative density and particle size polydispersity and inversely proportional to mean particle size. Furthermore, the capillary strengthening effect is also analysed microscopically in aid of the Stress–Force–Fabric relationship, mainly in fabric anisotropy, coordination number and stress transmission pattern, which revealed the micro-mechanisms of the additional effective stress induced by capillary effect.     

嫩江科洛地区晚侏罗世深熔花岗岩对嫩江-黑河构造带的响应

通过对嫩江-黑河构造带内的岩石建造研究,在嫩江科洛地区识别出一套深熔花岗岩体,岩石宏观上为一套具非典型花岗岩结构的深熔型侵入岩,具交代结构、斑杂状构造和眼球状构造。对深熔花岗岩进行了锆石LA-ICP-MS U-Pb年龄测试,获得了3组不谐和的U-Pb年龄: 390 Ma、157~163 Ma和113 Ma。其中,113 Ma年龄代表了岩石遭受后期变质热事件年龄; 157~163 Ma的年龄代表了原岩结晶年龄。综合分析深熔花岗岩成因,认为其主要与嫩江-黑河断裂深部韧性剪切热效应作用下发生的深熔有关,深熔花岗岩的划分和厘定为深入研究嫩江-黑河断裂带在中生代的活动提供了新的素材。     

粤东鸿沟山金矿区流纹斑岩锆石SHRIMP U-Pb定年、Lu-Hf同位素组成及其地质意义

鸿沟山矿区位于华南粤东莲花山钨矿床的中部,是近年来通过地质矿产调查新发现具有找寻金矿潜力的矿床之一。本文以与鸿沟山金等多金属矿化关系密切的流纹斑岩为研究对象,开展了锆石SHRIMP U-Pb定年、流纹斑岩和矿石岩石地球化学、锆石Lu-Hf同位素组成特征研究。获得流纹斑岩锆石206Pb/238U加权平均年龄为169.1±1.5Ma,说明岩体形成于中侏罗世。在微量元素特征方面,流纹斑岩都表现为相对亏损大离子亲石元素Ba、Sr和高强场元素Nb、P、Zr、Hf,富集大离子亲石元素Rb,高强场元素U、Ce、Sm和轻稀土元素La、Nd,流纹斑岩与矿石稀土元素特征基本相似,Eu具中等负异常,但随着矿化强度的增强稀土元素更加富集。流纹斑岩εHf(t)(-15.0~2.2)分布范围宽,二阶段模式年龄TDM2主要变化范围为0.82~0.93 Ga,表明成岩物质主要来源于新元古代古老地壳变质泥岩和变质砂岩部分熔融,并有幔源物质的加入。因此,围绕着该时间段的流纹斑岩岩体,对于找寻W、Cu、Pb、Zn、Bi、Au、稀土、稀有和稀散元素矿产具有重要意义。     

新特提斯洋俯冲起始的地质记录:土耳其南部蛇绿岩和变质底板

在现行板块构造理论的框架下,板块的初始俯冲是岩浆活动和构造运动发生转变的重要过程,亦是理解板块运动的关键节点。在俯冲起始过程中,主要存在四个方面的地质记录,分别为一系列地球化学成分多样的岩浆活动、SSZ型蛇绿岩、变质底板和玻安岩及其对应的铬铁矿床。特提斯造山带作为公认的研究板块构造理论尤其是初始俯冲的关键场所,一直备受地学界的重视。而土耳其南部构造带作为特提斯造山带的重要组成部分,亦是确定亚欧板块和阿拉伯板块之间缝合线存在的重要标志。该南部构造带是研究新特提斯洋俯冲起始的理想场所,上述关于俯冲初始的四个地质记录均保存良好,且有如下方面的重要特点:1)不同地区的镁铁质岩石甚至同一地区的镁铁质岩石具有不同的地球化学特征,从似洋中脊玄武岩,到过渡型岩石类型和玻安质岩石均有发育; 2)大部分蛇绿岩具有完整的序列,各单元及变质底板岩石中普遍发育侵入的基性岩脉,产状多变,是多期岩浆事件的产物; 3)蛇绿岩下部通常发育一套角闪岩相变质底板,且其年龄与蛇绿岩的形成年龄基本一致; 4)蛇绿岩中普遍发育铬铁矿床,以高Cr型为主,部分蛇绿岩中还赋存高Al-高Cr的过渡型铬铁矿,均被认为是幔源岩浆与地幔橄榄岩反应的产物。因而,这些地质体完整记录了新特提斯洋形成-俯冲-消减的演化过程。     

Disciplinary System and Development Strategy for Eco-hydrology

Eco-hydrology is a new discipline developed in recent decades. It is of great significance to accelerate and promote the development of eco-hydrology subject by constructing a perfect discipline system and formulating future development strategies. By reviewing a large number of literatures, this paper systematically combed and expounded the development and evolution of the eco-hydrology, which can be divided into five stages, the embryonic period of eco-hydrology (1970-1986), formulation terminology and the initial exploration period of eco-hydrology (1987-1991), discipline establishment and the initial development period of eco-hydrology (1992-1995), the rapid development period of eco-hydrology (1996-2007) and the improvement period of eco-hydrology (2008-present). Based on the analysis of the development of eco-hydrology, the disciplinary system of eco-hydrology was proposed as a framework of “theory-method-practice-branch discipline”. Finally, combined with the authors’ understanding, this paper put forward the development strategy system of the eco-hydrology, including the disciplinary research plan, the key research project, the country’s major demand, the discipline construction and the international cooperation, which will provide support for the promotion and establishment of a sound disciplinary system of eco-hydrology.     

江苏灌河入海口附近重金属元素环境地球化学质量分析

以往对灌河口附近海域进行地球化学调查发现,海底沉积物及海水质量总体良好,但局部沉积物中Cr含量高于一类标准,Cu、As、Pb、Hg等其他重金属元素含量也明显高于其他地区,个别重金属元素已接近一类标准最高限,存在潜在生态风险。为进一步了解其与人类活动是否有关,对灌河靠近入海口40 km长的河水进行了地球化学调查,发现灌河河水中Hg、Cu、Pb等重金属元素存在一定程度的超标现象。结合其他证据认为,人类活动不仅对灌河下游河水质量产生了负面影响,还对入海口附近的海域环境质量产生了潜在威胁。借鉴内梅罗综合指数评价思路对灌河下游及入海口的重金属元素环境质量进行评价,并对如何降低、消除生态风险提出了若干建议。     

Geochronology,Geochemistry and Petrogenesis of the Pungco Ophiolite,TibetEI北大核心CSCD

Although the middle section of the Bangong-Nujiang suture zone has been intensively investigated, its tectonic framework and evolution is still controversy. The Pungco ophiolite has a relative complete ophiolitic complex, which is an ideal specimen for studying this tricky problem. LA-ICP-MS U-Pb dating of zircons from the diabasic rock yielded an age of 159.0±2.1 Ma. This age suggests that the Pungco ophiolite was formed in the Late Jurassic, indicating the development of the Late Jurassic ophiolite in the third ophiolitic subzone. The whole-rock major and trace element compositions of diabasic and basaltic rocks exhibit mixed arc and N-MORB geochemical characteristics. Two diabasic samples have (87Sr/86Sr)i values of 0.7055 and 0.7063 and εNd(t) values of 11.28 and 11.84, respectively. The geochemical signatures and formation age of the Pungco ophiolite suggest that this ophiolite was probably produced in an active continental fore-arc setting. It originated from a N-MORB-like depleted mantle source with the involvement of subducted-slab fluids. Considering the regional geological background, the Pungco ophiolite was likely generated during the southward subduction of the Bangong-Nujiang Tethyan oceanic lithosphere beneath the Lhasa terrane, and belongs to a regional archipelagic arc-basin system together with the other Early Jurassic-Early Cretaceous ophiolites from the northern Tibet Lake district. © 2018, Science Press. All right reserved.     

The nonlinear time lag multivariable grey prediction model based on interval grey numbers and its application

Natural Hazards - The linear relationship of the original grey prediction model is too single, and the original grey prediction model does not consider the time delay of the effect of the current...