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321.
322.
从文蛤体中分离纯化得到了抗癌多肽,研究该多肽对N-乙酰-β-D-氨基葡萄糖苷酶(NAGase)活力的影响,结果显示文蛤抗癌多肽对该酶有明显的抑制作用.在本文中,我们将深入地研究其抑制作用机理和抑制效应类型,结果表明:随着文蛤多肽加入量的增大,该酶活力呈指数下降,测得导致酶活力下降50%的抑制剂浓度(IC50)为112.9 μg/cm3,该多肽对酶的抑制作用是一种可逆过程,抑制机理表现为混合型抑制类型,对游离酶(E)的抑制常数(KI)和酶-底物络合物的抑制常数(KIS)分别为77.03和697.44μg/cm3,说明文蛤抗癌多肽与游离酶的结合导致酶活力的丧失,明显的强于对酶-底物络合物的抑制效应,底物的存在对该酶被文蛤抗癌多肽抑制作用起了保护作用. 相似文献
323.
应用DFD(Diverse Firewall Design)方法进行防火墙规则集设计时,需使用规则集语义比较算法,判断多个规则集是否语义一致。规则冲突是导致规则集语义不一致的主要原因。因此,需要研究针对规则冲突的规则集语义比较算法。而现有算法时空复杂度较高,性能低下。文中提出了1种基于关键数据包选取映射的规则集语义比较算法(KPCM)。KPCM算法针对规则冲突选取关键数据包,并通过比较这些数据包在不同规则集中的处理动作,判断这些规则集是否语义一致。理论分析和测试表明,KPCM算法时空性能均优于现有算法。 相似文献
324.
Sensitivity of penman-monteith reference crop evapotranspiration in Tao’er River Basin of northeastern China 总被引:1,自引:0,他引:1
A non-dimensional relative sensitivity coefficient was employed to predict the responses of reference crop evapotranspiration (ET0) to perturbation of four climate variables in Tao'er River Basin of the northeastern China. Mean monthly ET0 and yearly ET0 from 1961 to 2005 were estimated with the FAO-56 Penman-Monteith Equation. A 45-year historical dataset of average monthly maximum/minimum air temperature, mean air temperature, wind speed, sunshine hours and relative humidity from 15 meteorological stations was used in the analysis. Results show that: 1) Sensitivity coefficients of wind speed, air temperature and sunshine hours were positive except for those of air temperature of Arxan Meteorological Station, while those of relative humidity were all negative. Relative humidity was the most sensitive variable in general for the Tao'er River Basin, followed by sunshine hours, wind speed and air temperature. 2) Similar to climate variable, monthly sensitivity coefficients exhibit large annual fluctuations. 3) Sensitivity coefficients for four climate variables all showed significant trends in seasonal/yearly series. Also, sensitivity coefficients of air temperature, sunshine hours and wind speed all showed significant trends in spring. 4) Among all sensitivity coefficients, the average yearly sensitivity coefficient of relative humidity was highest throughout the basin and showed largest spatial variability. Longitudinal distribution of sensitivity coefficients for air temperature, relative humidity and sunshine hours was also found, which was similar to the distribution of the three climate variables. 相似文献
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327.
Fatty acid composition and total lipid content of 8 strains of marine diatoms (Nitzschia frustrula, Nitzschia closterium, Nitzschia incerta, Navicula pelliculosa, Phaeodactylum tricornutum, Synedra fragilaroides) were examined. The microalgae were grown under defined conditions and harvested at the late exponential phase. The major
fatty acids in most strains were 14∶0 (1.0%–6.3%), 16∶0 (13.5–26.4%), 16∶1n−7 (21.1%–46.3%) and 20∶5n−3 (6.5%–19.5%). The
polyunsaturated fatty acids 16∶2n−4, 16∶3n−4, 16∶4n−1 and 20∶4n−6 also comprised a significant proportion of the total fatty
acids in some strains. The characteristic fatty acid composition of diatoms is readily distinguishable from those of other
microalgal groups. Significant concentration of the polyunsaturated fatty acid 20∶5n−3 (eicosapentaenoic acid) was present
in each strain, with the highest proportion in B222 (19.5%).
Project supported by the Hi-Tech “863” Programs of the China Ministry of Science and Technology (863-819-02-01). 相似文献
328.
SONG Peng TAN Jun LIU Zhaolun ZHANG Xiaobo LIU Baohua YU Kaiben LI Jinshan XIA Dongming XIE Chuang 《中国海洋大学学报(英文版)》2019,(4)
The gradient preconditioning approach based on seismic wave energy can effectively avoid the huge memory consumption of the gradient preconditioning algorithms based on the Hessian matrix. However, the accuracy of this approach is prone to be influenced by the energy of reflected waves. To tackle this problem, the paper proposes a new gradient preconditioning method based on the energy of transmitted waves. The approach scales the gradient through a precondition factor, which is calculated by the ‘approximate transmission wavefield' simulation based on the nonreflecting acoustic wave equation. The method requires no computing nor storing of the Hessian matrix and its inverse matrix. Furthermore, the proposed method can effectively eliminate the effects of geometric spreading and disproportionality in the gradient illumination. The results of model experiments show that the time-domain full waveform inversion(FWI) using the gradient preconditioning based on transmitted wave energy can achieve higher inversion accuracy for deep high-velocity bodies and their underlying strata in comparison with the one using the gradient preconditioning based on seismic wave energy. The field marine seismic data test shows that our proposed method is also highly applicable to the FWI of field marine seismic data. 相似文献
329.
The sea area east of Chenshan Cape has peak tidal current flows that exceed 2.3 m s-1, which make it a promising site for the development of tidal current energy. Before these resources can be exploited, a comprehensive assessment is needed of the potential environmental impacts of the extraction of this energy. In this paper, we describe our construction of a three-dimensional hydrodynamic model of the waters near Chengshan Cape, and verify the performance of the model using continuous data measured in situ. We modeled the potential impacts of the exploitation of these resources on the flow field by adding a momentum loss term in the governing equation of the model. Simulation results show that an assumed tidal farm with an estimated power output of 20.34 MW would have a significant impact on the surrounding water level, especially next to the farm, where fluctuation could reach 6 cm. The maximum drop in the flow velocity in the wake of the farm was predicted to be more than 0.8 m s-1, and this influence would extend 10 km downstream. 相似文献
330.
WANG Xiaoqiong ZHAO Yangguo WANG Junpeng ZHANG Mo BAI Jie GUO Liang GAO Mengchun 《中国海洋大学学报(英文版)》2019,(5)
To biologically inhibit the production of highly toxic sulfide in the aquaculture area, one bacterium, designated as Hydrogenovibrio thermophilus strain TT, was isolated from sediment in Jiaozhou Bay, China. The strain was found to be microaerobic mixtrophic, employing both carbon dioxide and organic carbons, e.g. citrate, lactate, glucose, and peptone as carbon sources. When it oxidized the sulfide and thiosulfate, oxygen was the optimal electron acceptor, followed by nitrite and nitrate, which benefited to removal of sulfide under low-oxygen mariculture environment. In addition, the strain TT exhibited remarkable tolerance of sulfide and thiosulfate in seawater, and it was able to oxidize 18.52 mmol L~(-1) S~(2-) in 12 h or 45 mmol L~(-1) S_2O_3~(2-) in 24 h at initial pH 7.0-9.0, 30-40℃. Therefore, this strain showed a quite promising application for biological remediation of sulfide-contaminated mariculture system. 相似文献