冈底斯新近纪钾质火山作用:消减沉积物折返的地球化学与Sr-Nd-Pb同位素证据

在冈底斯岩浆岩带的羊八井地区,林子宗火山岩系上部出现小规模的粗面质火山岩.岩石学与地球化学研究表明粗面岩与时空密切相关的大体积安山质-英安质-流纹质火山岩属于不同的火山岩系:碱性钾质系列与钙碱性系列.详细的地球化学研究证明林子宗晚期小体积钾质岩具有独立的岩浆源区,而非早期钙碱性系统低压岩浆过程演化的产物.粗面质熔岩SiO2含量为62.91%～64.63%,具有高K2O(7.52%～8.05%)、Al2O3(16.64%-17.35%)、低TiO2(0.59%～0.68%)与MsO(0.15%～0.77%).钾质熔岩富集LILE与LREE,亏损HFSE,具有高Rb/Sr(1.1～2.3)、Th/La(0.59～0.80)、Th/U(6.3～10.9)和低Ce/Pb(4.1～6.2)与Ba/Th(4.3～14.5)比值,其同位素组成变化范围分别是87Sr/86Sr(I)=0.7068～0.7075、143Nd/144Nd(I)=0.51241～0.51252、206Pb/204Pb=18.87～18.95、207Pb/204Pb=15.63～15.70和208Pb/204Pb=39.24～39.68.粗面岩的地球化学与同位素特征表明冈底斯新近纪钾质火山岩来源于角闪岩相的消减沉积物熔融.因此,羊八井新近纪钾质火山熔岩提供了印度-亚洲大陆碰撞早期消减沉积物折返的证据.     

Action of Cnoidal Waves on Vertical Walls

Based on the 2nd order cnoidal wave theory, the characters of shallow water standing waves and their action on vertical walls are studied in this paper. The theoretical expressions of the wave surface elevation in front of and the wave pressure on the vertical wall are obtained. In order to verify the theoretical results, model tests were made in the State Key Laboratory of Coastal and Offshore Engineering at DUT. For the wave surface elevation in front of the wall and the wave forces on the wall at the moment when the wave surface at the wall surface goes down to the bottom of the wave trough, the calculated results coincide quite well with the experimental results. For the wave forces on the wall at the moment when the wave surface at the wall surface goes up to the top of the wave crest, the theoretical expressions are modified by the experimental results. For the convenience of practical use, calculations are made for the wave conditions which usually occur in enginering practice by use of the inves     

Stability Design System of Submarine Pipelines

This paper introduces a stability design system of submarine pipelines. The system can provide a reasonable design procedure for users with reference to domestic and foreign methods and in the light of home engineering experience.     

A New Approach to High-Order Boussinesq-Type Equations with Ambient Currents

A new approach to high-order Boussinesq-type equations with ambient currents is presented. The current velocity is assumed to be uniform over depth and of the same magnitude as the shallow water wave celerity. The wave velocity field is expressed in terms of the horizontal and vertical wave velocity components at an arbitrary water depth level. Linear operators are introduced to improve the accuracy of the kinematic condition at the sea bottom. The dynamic and kinematic conditions at the free surface are expressed in terms of wave velocity variables defined directly on the free surface. The new equations provide high accuracy of linear properties as well as nonlinear properties from shallow to deep water, and extend the applicable range of relative water depth in the case of opposing currents.     

Wave Loads and Protective Techniques of An On-Shore Wave Power Device

In this paper, the extreme wave loads on an on-shore wave power device are investigated. First, boundary element method is applied to solve the three dimensional potential problem based on the small amplitude wave assumption. Then the motion of the Oscillating Water Column (OWC) inside the device and its laods on the device are calculated in time domain. Several protective techniques often applied are simulated by changing the constraint of the upper end of the chamber of the device. Numerical results are used to judge the effectiveness of these techniques. The investigation shows that damping can not effectively restrain the motion of OWC when the period of incident wave is long, which may cause dangerous loads on the structure. The shut chamber can effectively restrain the motion of OWC, but alternatively cause high pressure in the chamber. A Contracting opening with a Taper (CT) can exhaust a great amount of kinetic energy of OWC, and significantly decrease the loads. It is a promising protective tec     

Design of a caisson plate under wave impact

From the laboratory experiments and field studies it has been shown that when a wave breaks directly on a vertical wall, impact pressures of high magnitude and short duration, are produced. Despite the recent advances made in collecting data on impact pressure histories and their spatial distributions, analyses on the structural behaviour of the walls loaded by the impact forces do not seem adequate. In the present study the theoretical analysis of the response characteristics of a caisson plate, having different aspect ratios, under the wave impact loading is investigated. Numerical results for the dynamic values of moments and transverse displacements are obtained by the method of finite elements. Some prerequisite experimental data for wave breaking and resulting impact pressures are provided. The static results for moments and deflections are also computed for comparing them with the dynamic values. The dynamic results are found significantly greater than the static values. The ratio between the dynamic and static values is called “Dynamic magnification factor” that varies with plate aspect ratio. Based on this factor a procedure is proposed which may have practical consequences in the design of caisson plates.     

Fractal Dimension and Fractals in Ocean Engineering

- This paper discusses the application of fractal dimension and fractals in ocean engineering. To handle some ocean environment problems, the existing fractal method, in which the fractal dimension is a constant, can be used. For some complicated problems in ocean engineering, this paper presents the concept of the variable dimension fractals (D = f(r)), i. e., the fractal dimension D is the function of characteristic scale r instead of a constant. By using variable dimension fractals, several deformation and stress states of offshore structures are described.     

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。     

A Unified Variational Principle of Fluid Mechanics and Application on Solitary Subdomain or Point

-According to basic equations of fluid mechanics, this paper presents a unified variational principle of fluid mechanics (UVPFM) by using the optimization method of weighted residuals (OMWR). The advantages are as follows, the establishment of the functional and the variational principle is easy, it can change various problems of fluid mechanics derived by basic equations into a unified optimization problem, and the solution is the optimum one in some sense. According to the OMWR for the solitary subdomain, this paper uses UVPFM onto any solitary subdomain and gives the solution of the hydrodynamics equation which is suitable only for that solitary subdomain. According to the OMWR for solitary point, this paper uses UVPFM to any solitary point and gives the solution of the hydrodynamics equation (point solution) which is suitable only for that solitary point. As the solution for the solitary subdomain or solitary point is developed independently, the compatibility with other subdomain or other points, do