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1.
1INTRODUCTIONClusters,definedasgeographicallyproximategroupsofinterconnectedcompaniesandassociatedinstitutionsinparticularfields,linkedbycommonalitiesandcomple-mentarities(PORTER,2000),havearousedanintenseinterestofurbanandregionalplanningresearchersandpolicymakersoverthepastdecades.Itiswidelyrecog-nizedthatclusterscanpromoteproductivityandinno-vation,developlocalcompetitiveadvantages.Popular-izedbyMichaelPORTERinhisbook“TheCompetitiveAdvantageofNationsin1990,theclusterisnotanewcon…  相似文献   
2.
Two nemerteans of the Zhoushan Islands, Paranemertes sinensis sp. nov. and P. peregrina, are reportedin this paper. P. sinensis sp. nov. has the body wall longitudinal musculature anteriorly divided,numerous eyes grouped into four clusters, two pairs of cephalic furrows, rhynchocoel 1/3 to 1/2 of fullbody length, cephalic glands well developed and posteriorly extending beyond the cerebral ganglia.precerebral septum absent, cerebral sense organs situated in front of brain, three pairs of nephridiopores,and 17-18 proboscis nerves.  相似文献   
3.
目的:基于生物信息学探讨骨质疏松症与 2 型糖尿病的关系。方法:通过基因表达汇编(GEO)数据库检索骨质疏松症和2型糖尿病的相关数据集,并筛选骨质疏松症-2型糖尿病共同差异表达基因,将数据导入STRING数据库找寻关键基因,以一个单细胞测序数据集作为检验集验证关键基因细胞层面的表达水平,对筛选结果进行基因本体(GO)功能及京都基因与基因组百科全书(KEGG)通路富集分析,并对关键靶点、相关中药进行频数统计及功效分类。结果:骨质疏松症与 2 型糖尿病相关通路集中在 ErbB信号通路、丝活化蛋白激酶(MAPK)信号通路、神经营养素信号通路、NOD样受体信号通路。频数统计结果显示,与骨质疏松症-2型糖尿病关键基因相关的中药有51味,以功效分类,可分为清热解毒药、止痛药、祛风药、补虚药、止呕药。结论:骨质疏松症和2型糖尿病都是复杂的代谢性疾病,涉及众多基因表达网络和信号通路。尽管两种疾病存在复杂的基因网络背景,但是分析结果表明两种疾病之间仍存在高度重合的差异基因表达和信号通路。这表明两种疾病的分子机制密切相关,可能存在共同调控的靶点,因此这些靶点可能成为药物同时干预两种疾病的治疗靶点。  相似文献   
4.
Inhomogeneous substrate analysis using EM300 backscatter imagery   总被引:2,自引:0,他引:2  
Backscatter reflectivity from multibeam echo-sounders provides a powerful tool to efficiently characterize seafloor substrates. A comprehensive EM300 bathymetric and backscatter survey has been completed of Cook Strait, in central New Zealand. This paper presents a detailed analysis of the realtime corrections applied to the raw EM300 multibeam data and additional corrections required to compute angular variations of the backscatter strength. The corrections, including the local absorption coefficient, the influence of seafloor topography and sound refraction in the water column, are determined for different Cook Strait seafloor substrates. Modifying MB-System software code, we extracted the backscatter signal parameters in order to quantify the raw backscatter strength and apply additional processing. Profiles of backscatter strength versus incidence angle were computed for a variety of sites characterized by flat seafloor and homogeneous substrates, and for which ground-truth data were available. For each homogeneous site, different but characteristic backscatter profiles are observed that can be interpreted in terms of sediment facies. To analyze heterogeneous substrates, we present a statistical technique, based on a 3-dimensional distribution of (incidence angle, backscatter strength) couples that preserves geological information of the substrate components. This analysis, using backscatter data acquired on a submarine volcano, north of New Zealand, clearly differentiates soft sediments and lava flows within a heterogeneous substrate.  相似文献   
5.
Pristane (2,6,10,14 -tetramethylpentadecane) occurs ubiquitously in the marine environment. This hydrocarbon may be of biogenic or petrogenic origin.1 Recently it has been shown that residual amounts of this branched alkane increased in marine organisms after an oil spill.2,3 The lack of data on the fate of pristane in fish, added with the fact that this compound was considered by some authors as a non-metabolisable substance in vertebrates, including man,4 led us to investigate the capability of fish to metabolise pristane. In this study, urinary and fecal excretion, tissue distribution and metabolism of 3H-pristane were analysed in Salmo gairdneri R. after a single intragastric dose. In addition to unchanged hydrocarbon, various labelled compounds have been isolated and identified in liver, bile, faeces, urine and surrounding water, demonstrating that pristane was first oxidised to alcohols (pristanol and pristane-diol) and to acid (pristanic acid). The elimination of these compounds occurred in the form of conjugated products (primarily glucuronides) as well as free metabolites.  相似文献   
6.
The use of diving animals as autonomous vectors of oceanographic instruments is rapidly increasing, because this approach yields cost-efficient new information and can be used in previously poorly sampled areas. However, methods for analyzing the collected data are still under development. In particular, difficulties may arise from the heterogeneous data distribution linked to animals’ behavior. Here we show how raw temperature data collected by penguin-borne loggers were transformed to a regular gridded dataset that provided new information on the local circulation off Kerguelen. A total of 16 king penguins (Aptenodytes patagonicus) were equipped with satellite-positioning transmitters and with temperature–time–depth recorders (TTDRs) to record dive depth and sea temperature. The penguins’ foraging trips recorded during five summers ranged from 140 to 600 km from the colony and 11,000 dives >100 m were recorded. Temperature measurements recorded during diving were used to produce detailed 3D temperature fields of the area (0–200 m). The data treatment included dive location, determination of the vertical profile for each dive, averaging and gridding of those profiles onto 0.1°×0.1° cells, and optimal interpolation in both the horizontal and vertical using an objective analysis. Horizontal fields of temperature at the surface and 100 m are presented, as well as a vertical section along the main foraging direction of the penguins. Compared to conventional temperature databases (Levitus World Ocean Atlas and historical stations available in the area), the 3D temperature fields collected from penguins are extremely finely resolved, by one order finer. Although TTDRs were less accurate than conventional instruments, such a high spatial resolution of penguin-derived data provided unprecedented detailed information on the upper level circulation pattern east of Kerguelen, as well as the iron-enrichment mechanism leading to a high primary production over the Kerguelen Plateau.  相似文献   
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8.
研究表明 :腐屑食性鱼类——梭鱼对环境中有机氮的摄入能力随体重的增加而增加 ,随温度的升高 ,体重系数显著减少。摄入氮 (CN,mg/ d)与体重 (W,g)和温度 (T,℃ )的数值关系可用如下模型表示 :CN=0 .6 370 W1 .0 642 ln(3.70 0 8T)。体重为 1 0 0 g的梭鱼每日可消耗环境中 332 mg氮有机质。梭鱼氮的吸收效率主要受温度的影响 ,而氮的转化效率与体重呈显著的正相关关系。随体重的增加 ,排泄氮所占比例降低  相似文献   
9.
用不同含量的93-B型海洋植物营养素对几种常用的金藻类饵料种进行培养对比试验。结果表明,海洋植物营养素用于培养金藻类效果良好,最适使用含量为30mp·L~-1域40mg·L~-1。此时效果与通常被推荐的培养液所培养的对照组相当或更好.含量过高,则造成某些营养盐过量而产生一定的毒害作用。此营养素使用简便。  相似文献   
10.
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