Production of the Blood Pressure Lowing Peptides from Brown Alga ( Undaria pinnatifida )

1 IntroductionIncreased blood pressure appears to be one of theprimary risk factors of circulatory organ diseases suchas encepharo-apoplexy, encepharo-infarction and cardi-ac infraction. Angiotensin-I-converting enzyme (ACE)plays an important role in the rennin-angiotensin sys-tem by regulating blood pressure. Antihypertensivedrugs such as captopril and enalapril are potent ACEinhibitors (Ondetti et al., 1977). Recently, severalinhibitory peptides derived from food proteins havebeen isolat…     

The Meteoritical Bulletin,No. 106

Meteoritical Bulletin 106 contains 1868 meteorites including 10 falls (Aiquile, Broek in Waterland, Degtevo, Dingle Dell, Dishchii'bikoh, Hradec Králové, Kheneg Ljouâd, Oudiyat Sbaa, Serra Pelada, Tres Irmaos), with 1386 ordinary chondrites, 166 carbonaceous chondrites, 119 HED achondrites, 48 Lunar meteorites, 37 iron meteorites, 36 ureilites, 19 Martian meteorites, 13 enstatite chondrites, 12 Rumuruti chondrites, 9 primitive achondrites, 8 mesosiderites, 5 enstatite achondrites, 4 ungrouped achondrites, 4 pallasites, and 1 relict meteorite. A total of 958 meteorites are from Africa, 405 from Antarctica, 245 from Asia, 228 from South America, 12 from North America, 8 from Europe, 5 from Mars, 4 from Oceania, and 1 from an unknown location.     

Oxygen isotope signatures in bulk chondrules: Implications for the aqueous alteration and thermal metamorphism on the Allende CV3 parent body

Precise triple oxygen isotope compositions of 32 Allende bulk chondrules (ABCs) are determined using laser‐assisted fluorination mass spectrometry. Various chemically characterized chondrule types show ranges in δ¹⁸O that vary from ?4.80‰ to +1.10‰ (porphyritic olivine; PO, N = 15), ?3.10‰ to +1.50‰ (porphyritic olivine pyroxene; POP, N = 9), ?3.40‰ to +2.60‰ (barred olivine; BO, N = 4), and ?3.60‰ to +1.30‰ (porphyritic pyroxene; PP, N = 3). Oxygen isotope data of these chondrules yield a regression line referred to as the Allende bulk chondrule line (ABC line, slope = 0.86 ± 0.02). Most of our data fall closer to the primitive chondrule minerals line (PCM line, slope = 0.987 ± 0.013) and the carbonaceous chondrite anhydrous mineral line (CCAM line, slope = 0.94 ± 0.02) than the Allende anhydrous mineral line (AAML, slope = 1.00 ± 0.01) with a maximum δ¹⁸O value (+2.60‰) observed in a BO chondrule and a minimum δ¹⁸O value (?4.80‰) shown by a PO chondrule. Similarly, these chondrules depict variable ?¹⁷O values that range from ?5.65‰ to ?3.25‰ (PO), ?4.60‰ to ?2.80‰ (POP), ?4.95‰ to ?3.00‰ (BO), ?5.30‰ to ?3.20‰ (PP), and ?4.90‰ (CC). A simple model is proposed for the Allende CV3 chondrite with reference to the AAML and PCM line to illustrate the isotopic variations occurred due to the aqueous alteration processes. The estimated temperature ranging from 10 to 130 °C (mean ~60 °C) implies that the secondary mineralization in Allende happened in a warmer and relatively dry environment compared to Murchison. We further propose that thermal metamorphism could have dehydrated the Allende matrix at temperatures between >150 °C and <600 °C.     

Genetic diversity and population structure of the golden cuttlefish,Sepia esculenta (Cephalopoda: Sepiidae) indicated by microsatellite DNA variations

The golden cuttlefish, Sepia esculenta Hoyle, 1885 (Cephalopoda: Sepiidae) is a valuable and important fishery resource for China, Japan and Korea. This fishery has experienced severe population decline largely due to overexploitation in past decades. To provide guidelines for fisheries management, we estimated genetic diversity and population structure across four locations along the coast of Japan and one location in China (a total 281 individuals) using nine microsatellite DNA loci. Sepia esculenta showed high genetic variability with mean allele richness ranging from 15.8 to 21.4, and mean heterozygosity from 0.80 to 0.90. Weak but significant genetic differentiation was present and the F_ST value was 0.020 across all five populations. The useful information obtained in this study will offer insights into how to fine‐tune conservation and fishery management measures for this species and resource in the future.     

Volume transport in the Soya Strait during 2006–2008

Time-series data of the vertical structure of the Soya Warm Current (SWC) were obtained by a bottom-mounted acoustic Doppler current profiler (ADCP) in the middle of the Soya Strait from September 2006 to July 2008. The site of the ADCP measurement was within the coverage of the ocean-radar measurement around the strait. The volume transport of the SWC through the strait is estimated on the basis of both the vertical structure observed by the ADCP and the horizontal structure observed by the radars for the first time. The annual transport estimates are 0.62–0.67 Sv (1 Sv = 10⁶ m³s⁻¹). They are somewhat smaller than the difference between the previous estimates of the inflow and outflow through other straits in the Sea of Japan, and smaller than those obtained in the region downstream of the strait during 2004–05 (0.94–1.04 Sv). The difference in the two periods may be attributed to interannual variability of the SWC and/or the different measurement locations.     

Climate and vegetation in Hokkaido, northern Japan, since the LGM: Pollen records from core GH02-1030 off Tokachi in the northwestern Pacific

Vegetation and climate since the LGM in eastern Hokkaido were investigated based on a pollen record from marine core GH02-1030 from off Tokachi in the northwestern Pacific. We also examined pollen spectra in surface samples from Sakhalin to compare and understand the climatic conditions of Hokkaido during the last glacial period. Vegetation in the Tokachi region in the LGM (22–17 ka) was an open boreal forest dominated by Picea and Larix. During the last deglaciation (17–10 ka), vegetation was characterized by abundant Betula. In the Kenbuchi Basin, central Hokkaido, a remarkable increase of Larix and Pinus occurred in the LGM and the last deglaciation, which was assigned as the “Kenbuchi Stadial.” Comparison of climatic data between the core GH02-1030 and that of Kenbuchi Basin demonstrates that variations in temperature and precipitation were larger in inland Hokkaido than in the maritime area of the Pacific coast. During the LGM in the Tokachi region, the August mean temperature was about 5 °C lower, and annual precipitation was about 40% lower than today. In the Kenbuchi Basin, central Hokkaido, the August mean temperature was about 8 °C lower, and annual precipitation was half that of today. During the last deglaciation, August mean temperatures were about 3 °C lower, and annual precipitation was about 30% lower than today in the Tokachi region. In the Kenbuchi Basin, August mean temperatures were about 5–8 °C lower, and annual precipitation was about 40–60% lower than today. Cold ocean water and a strengthened summer monsoon after 15 ka may have resulted in the formation of advection fogs, reduced summer temperatures, and a decrease in the seasonal temperature difference in the Tokachi district, which established favorable maritime conditions for Betula forests.     

Late Quaternary tephrostratigraphy of Baegdusan and Ulleung volcanoes using marine sediments in the Japan Sea/East Sea

Only Ulleung and Baegdusan volcanoes have produced alkaline tephras in the Japan Sea/East Sea during the Quaternary. Little is known about their detailed tephrostratigraphy, except for the U–Oki and B–Tm tephras. Trace element analysis of bulk sediments can be used to identify alkaline cryptotephra because of the large compositional contrast. Five sediment cores spanning the interval between the rhyolitic AT (29.4 ka) and Aso-4 (87 ka) tephras were analyzed using an INAA scanning method. Source volcanoes for the five detected alkaline cryptotephra were identified from major element analyses of hand-picked glass shards: Ulleung (U–Ym, and the newly identified U–Sado), and Baegdusan (B–J, and the newly identified B–Sado and B-Ym). The eruption ages of the U–Ym, U–Sado, B–J, B–Sado, and B–Ym tephras are estimated to be 38 ka, 61 ka, 26 ka, 51 ka, 68–69 ka, and 86 ka, respectively, based on correlations with regional-scale TL (thinly laminated) layer stratigraphy (produced by basin-wide changes in bottom-water oxygen levels in response to millennium-scale paleoclimate variations). This study has allowed construction of an alkaline tephrostratigraphical framework for the late Quaternary linked to global environmental changes in the Japan Sea/East Sea, and improves our knowledge of the eruptive histories of Ulleung and Baegdusan volcanoes.     

The effects of the tidal force on shear instabilities in the dust layer of the solar nebula

The linear analysis of the instability due to vertical shear in the dust layer of the solar nebula is performed. The following assumptions are adopted throughout this paper: (1) The self-gravity of the dust layer is neglected. (2) One fluid model is adopted, where the dust aggregates have the same velocity with the gas due to strong coupling by the drag force. (3) The gas is incompressible. The calculations with both the Coriolis and the tidal forces show that the tidal force has a stabilizing effect. The tidal force causes the radial shear in the disk. This radial shear changes the wave number of the mode which is at first unstable, and the mode is eventually stabilized. Thus the behavior of the mode is divided into two stages: (1) the first growth of the unstable mode which is similar to the results without the tidal force, and (2) the subsequent stabilization due to an increase of the wave number by the radial shear. If the midplane dust/gas density ratio is smaller than 2, the stabilization occurs before the unstable mode grows largely. On the other hand, the mode grows faster by one hundred orders of magnitude, if this ratio is larger than 20. Because the critical density of the gravitational instability is a few hundreds times as large as the gas density, the hydrodynamic instability investigated in this paper grows largely before the onset of the gravitational instability. It is expected that the hydrodynamic instability develops turbulence in the dust layer and the dust aggregates are stirred up to prevent from settling further. The formation of planetesimals through the gravitational instabilities is difficult to occur as long as the dust/gas surface density ratio is equal to that for the solar abundance. On the other hand, the shear instability is suppressed and the planetesimal formation through the gravitational instability may occur, if dust/gas surface density ratio is hundreds times as large as that for the solar abundance.     

Space astronomy in Japan

Japan's two X-ray astronomy satellites, HAKUCHO and TENMA, have been actively in operation leading to deeper understandings of the neutron star physics. Other satellite and balloon projects have been performed under international collaborators.Paper presented at the IAU Third Asian-Pacific Regional Meeting, held in Kyoto, Japan, between 30 September–6 October, 1984.