Protective effects of C-phycocyanin on alcohol-induced acute liver injury in mice

Excessive alcohol consumption leads to liver disease. Extensive evidence suggests that C-phycocyanin (C-PC), a chromophore phycocyanobilin derived from Spirulina platensis, exerts protective effects against chemical-induced organ damage. In this study, we investigated whether C-PC could protect against ethanol-induced acute liver injury. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), triglyceride (TG), total cholesterol (CHOL), low-density lipoprotein (LDL), liver homogenate malondialdehyde (MDA), superoxide dismutase (SOD) content were measured, and pathological examination of liver sections were examined. C-PC showed obvious inhibitory effects on serum ALT, AST, TG, CHOL, LDL and MDA, and SOD content significantly increased in the liver. The structure of hepatic lobules was clear, liver sinus returned to normal, and liver cell cords were arranged in neat rows. Cloudiness, swelling, inflammatory cell infiltration and spotty necrosis of liver cells were significantly reduced. Therefore, C-PC can significantly protect against ethanol-induced acute liver injury.     

Characteristics and cause analysis of heavy haze in Changchun City in Northeast China

Northeast China has been reported as having serious air pollution in China with increasing occurrences of severe haze episodes. Changchun City, as the center of Northeast China, has longstanding industry and is an important agricultural base. Additionally, Changchun City has a long winter requiring heating of buildings emitting pollution into the air. These factors contribute to the complexity of haze pollution in this area. In order to analyze the causes of heavy haze, surface air quality has been monitored from 2013 to 2015. By using satellite and meteorological data, atmospheric pollution status, spatio-temporal variations and formation have been analyzed. Results indicated that the air quality in 88.9% of days exceeding air quality index(AQI) level-1 standard(AQI 50) according to the National Ambient Air Quality Standard(NAAQS) of China. Conversely, 33.7% of the days showed a higher level with AQI 100. Extreme haze events(AQI 300) occurred frequently during agricultural harvesting period(from October 10 to November 10), intensive winter heating period(from Late-December to February) and period of spring windblown dust(April and May). Most daily concentrations of gaseous pollutants, i.e., NO_2(43.8 μg/m~3), CO(0.9 mg/m~3), SO_2(37.9 μg/m~3), and O_3(74.9 μg/m~3) were evaluated within level-1 concentration limits of NAAQS standards. However, particulate matter(PM_(2.5) and PM10) concentrations(67.3 μg/m~3 and 115.2 μg/m~3, respectively) were significantly higher than their level-1 limits. Severe haze in spring was caused by offsite transported dust and windblown surface soil. Heavy haze periods during fall and winter were mainly formed by intensive emissions of atmospheric pollutants and steady weather conditions(i.e., low wind speed and inversion layer). The overlay emissions of widespread straw burning and coal combustion for heating were the dominant factors contributing to haze in autumn, while intensive coal burning during the coldest time was the primary component of total emissions. In addition, general emissions including automobile exhaust, road and construction dust, residential and industrial activities, have significantly increased in recent years, making heavy haze a more frequent occurrence. Therefore, both improved technological strategies and optimized pollution management on a regional scale are necessary to minimize emissions in specified seasons in Changchun City, as well as comprehensive control measures in Northeast China.     

Understanding the implications of the EU-LULUCF regulation for the wood supply from EU forests to the EU

Background

In June 2018, the European Parliament and Council of the European Union adopted a legislative regulation for incorporating greenhouse gas emissions and removals from Land Use, Land Use Change and Forestry (EU-LULUCF) under its 2030 Climate and Energy Framework. The LULUCF regulation aim to incentivise EU Member States to decrease greenhouse gas emissions and increase removals in the LULUCF sector. The regulation, however, does not set a target for increasing the LULUCF carbon sink, but rather includes a ‘no net debit’ target for LULUCF (Forests and Agricultural soils). For Managed Forest Land (MFL) an accounting framework with capped credits for additional mitigation against a set forest reference level (FRL) was agreed for 2021–2030. The FRL gives the projected future carbon sink in the two compliance periods 2021–2025 and 2026–2030 under “continuation of forest management practices as they were in the reference period 2000–2009”. This FRL was disputed by some Member States as it was perceived to put a limit on their future wood harvesting from MFL. Here we simulated with the EFISCEN European forest model the “continuation of forest management practices” and determined the corresponding wood harvest for 26 EU countries under progressing age classes.

Results

The simulations showed that under “continuation of forest management practices” the harvest (wood removals) in the 26 EU countries as a whole can increase from 420 million m³/year in 2000–2009 to 560 million m³/year in 2050 due to progressing age classes. This implies there is a possibility to increase absolute wood harvests without creating debits compared to the forest reference level. However, the manner in which ‘continuation of forest management’ developed with a progressing age class development over time, meant that in some countries the future harvesting exceeded 90% of the increment. Since this generally is considered to be unsustainable we additionally set a harvesting cut-off as max 90% of increment to be harvested for each individual country as a possible interpretation of sustainability criteria that are included in the regulation. Using this additional limit the projected harvest will only increase to 493 million m³/year.

Conclusions

The worry from Member States (MS) that the FRL will prevent any additional harvesting seems unwarranted. Due to differences between Member States concerning the state of their forest resources, the FRL as a baseline for harvesting works out very differently for the different Member States. The FRL may have other unforeseen consequences which we discuss. Under all scenarios the living forest biomass sink shows a decline. This can be counteracted through incentivising measures under Climate Smart Forestry.

     

The Impact of Irrigation on Bacterial Community Composition and Diversity in Liaohe Estuary Wetland

In this study, the sequencing of 16S ribosomal DNA was used to characterize the soil bacterial community composition and diversity in Liaohe estuarine wetland. Soil samples were taken from different locations in the wetland dominated by reed. Moreover, the soil quality parameters were evaluated (pH, moisture, organic matter, total nitrogen, available nitrogen, total phosphorus, available phosphorus). The results showed that the organic matter and nutrient contents were significantly higher in irrigated wetland than those in natural wetland. Major phylogenic groups of bacteria in soil samples including Proteobacteria, Acidobacteria, Gemmatimonadetes, Actinobacteria and Cyanobacteria were analyzed and we found that Proteobacteria was the most abundant in the community, and the phylum Acidobacteria was more abundant in irrigated wetland. Beta diversity analyses indicated that the soil bacterial community was mainly affected by sampling sites rather than seasons. In general, the bacterial community in natural wetland was not significantly different with that in artificial irrigated wetland. Artificial hydraulic engineering irrigated according to the water requirement rule of reed, increased the production of reeds, changed the way of wetland soil material input, but the diversity of bacterial community kept stable relatively.     

Limit equilibrium method (LEM) of slope stability and calculation of comprehensive factor of safety with double strength-reduction technique

When the slope is in critical limit equilibrium(LE) state, the strength parameters have different contribution to each other on maintaining slope stability. That is to say that the strength parameters are not simultaneously reduced. Hence, the LE stress method is established to analyze the slope stability by employing the double strengthreduction(DSR) technique in this work. For calculation model of slope stability under the DSR technique, the general nonlinear Mohr–Coulomb(M–C) criterion is used to describe the shear failure of slope. Meanwhile, the average and polar diameter methods via the DSR technique are both adopted to calculate the comprehensive factor of safety(FOS) of slope. To extend the application of the polar diameter method, the original method is improved in the proposed method. After comparison and analysis on some slope examples, the proposed method's feasibility is verified. Thereafter, the stability charts of slope suitable for engineering application are drawn. Moreover, the studies show that:(1) the average method yields similar results as that of the polardiameter method;(2) compared with the traditional uniform strength-reduction(USR) technique, the slope stability obtained using the DSR techniquetends to be more unsafe; and(3) for a slope in the critical LE state, the strength parameter φ, i.e., internal friction angle, has greater contribution on the slope stability than the strength parameters c, i.e., cohesion.     

WSO and the winds of massive stars: the gate to the metal-poor Local Universe

The spectrographs on-board the World Space Observatory (WSO) will provide access to the 1020–1800 Å wavelength range with unprecedented sensitivity. Previous observatories operating in the 1150–2000 Å range (such as IUE and HST-STIS) have proved extremely useful to study the winds of OB type stars, which leave their most prominent imprints in the far ultraviolet range. The addition of the λ < 1200 Å wavelengths is critical as it contains important diagnostic lines for mass loss and shocks in the wind, as found by FUSE-based analyses.WSO will enable quantitative spectroscopic analyses of blue massive stars in the Local Group beyond the Magellanic Clouds. The results will lead to the characterization of their winds as a function of metallicity, and shed new light on current urging questions regarding radiation driven winds.     

On the use of logistic regression for stellar classification

We are totally immersed in the Big Data era and reliable algorithms and methods for data classification are instrumental for astronomical research. Random Forest and Support Vector Machines algorithms have become popular over the last few years and they are widely used for different stellar classification problems. In this article, we explore an alternative supervised classification method scarcely exploited in astronomy, Logistic Regression, that has been applied successfully in other scientific areas, particularly biostatistics. We have applied this method in order to derive membership probabilities for potential T Tauri star candidates from ultraviolet-infrared colour-colour diagrams.     

An attempt to test Ambartsumian's idea of the origin of the galaxy . II. location of galaxies within clusters and galaxy position angles

The location of galaxies in 377 rich Abell galaxy clusters is discussed. We compared the distributions of galaxies in the sample containing all galaxies with the sample compiled from the 20 brightest objects. Counts in circular sectors with angle width equal to 30î show isotropy. Only in the case of BM I clusters and the coordinate system related to the cluster major axis did we find anisotropic distributions. We investigated also the distributions of galaxy position angles within clusters exhibiting isotropy. The structure position angles for both samples have been studied as well. They appeared to be different. The difference in location of galaxies in the case of cD clusters, as well as the more elliptical shape and different position angles of samples containing bright galaxies is observed.     

The influence of rainfall and land use patterns on soil erosion in multi-scale watersheds: A case study in the hilly and gully area on the Loess Plateau,China

Soil erosion has become a major global environmental problem and is particularly acute on the Loess Plateau (LP), China. It is therefore highly important to control this process in order to improve ecosystems, protect ecological security, and maintain the harmonious relationship between humans and nature. We compared the effects of rainfall and land use (LU) patterns on soil erosion in different LP watersheds in this study in order to augment and improve soil erosion models. As most research on this theme has so far been focused on individual study areas, limited analyses of rainfall and LU patterns on soil erosion within different- scale watersheds has so far been performed, a discrepancy which might influence the simulation accuracies of soil erosion models. We therefore developed rainfall and LU pattern indices in this study using the soil erosion evaluation index as a reference and applied them to predict the extent of this process in different-scale watersheds, an approach which is likely to play a crucial role in enabling the comprehensive management of this phenomenon as well as the optimized design of LU patterns. The areas considered in this study included the Qingjian, Fenchuan, Yanhe, and Dali river watersheds. Results showed that the rainfall erosivity factor (R) tended to increase in these areas from 2006 to 2012, while the vegetation cover and management factor (C) tended to decrease. Results showed that as watershed area increased, the effect of rainfall pattern on soil erosion gradually decreased while patterns in LU trended in the opposite direction, as the relative proportion of woodland decreased and the different forms of steep slope vegetation cover became more homogenous. As watershed area increased, loose soil and craggy terrain properties led to additional gravitational erosion and enhanced the effects of both soil and topography.     

A back-propagation neural-network-based displacement back analysis for the identification of the geomechanical parameters of the Yonglang landslide in China

Xigeda formation is a type of hundred-meter-thick lacustrine sediments of being prone to triggering landslides along the trunk channel and tributaries of the upper Yangtze River in China. The Yonglang landslide located near Yonglang Town of Dechang County in Sichuan Province of China, which was a typical Xigeda formation landslide, was stabilized by anti-slide piles. Loading tests on a loading-test pile were conducted to measure the displacements and moments. The uncertainty of the tested geomechanical parameters of the Yonglang landslide over certain ranges would be problematic during the evaluation of the landslide. Thus, uniform design was introduced in the experimental design, and by which, numerical analyses of the loading-test pile were performed using Fast Lagrangian Analysis of Continua (FLAC^3D) to acquire a database of the geomechanical parameters of the Yonglang landslide and the corresponding displacements of the loading-test pile. A three-layer back-propagation neural network was established and trained with the database, and then tested and verified for its accuracy and reliability in numerical simulations. Displacement back analysis was conducted by substituting the displacements of the loading-test pile to the well-trained three-layer back-propagation neural network so as to identify the geomechanical parameters of the Yonglang landslide. The neural-network-based displacement back analysis method with the proposed methodology is verified to be accurate and reliable for the identification of the uncertain geomechanical parameters of landslides.