天降血栓通丸对2型糖尿病大鼠血糖、大血管病变的影响

目的：研究天降血栓通丸对2型糖尿病大鼠血糖、大血管病变的影响。方法：将90只wistar大鼠随机分为正常组15只与造模组75只,通过高糖高脂饲料+链脲佐菌素诱导建立糖尿病大鼠模型,造模成功后将其随机分为模型组,天降血栓通丸早期干预组、中期干预组、晚期干预组（简称为早期组、中期组、晚期组）,盐酸吡格列酮组（西药组）,每组各15只,分别采用相应药物干预。观察大鼠一般情况,检测空腹血糖、胰岛素、胰岛素敏感指数、细胞间黏附分子-1（ICAM-1）水平。结果：造模组与空白组比较,胰岛素、胰岛素敏感指标、体质量、第13周空腹血糖差异均有统计学意义（P＜0.01或P＜0.05）;药物干预后空腹血糖水平ICAM-1模型组、各治疗组与空白组比较,各治疗组与模型组比较,差异均有统计学意义（P＜0.05）。结论：天降血栓通丸无降糖作用,其早期干预能有效降低ICAM-1,这可能是其对2型糖尿病大鼠大血管病变影响的机制之一。     

Effects of stocking density on the growth and immunity of Atlantic salmon salmo salar reared in recirculating aquaculture system(RAS)

Atlantic salmon reared in recirculating aquaculture system(RAS) may lead to inappropriately high stocking density, because ?sh live in a limited space. Finding the suitable stocking density of Atlantic salmon reared in RAS is very important for RAS industry. In this paper, the in?uence of stocking density on growth and some stress related physiological factors were investigated to evaluate the ef fects of stocking density. The ?sh were reared for 220 days at ?ve densities(A: 24 kg/m^3; B: 21 kg/m^3; C: 15 kg/m^3; D: 9 kg/m^3 and E: 6 kg/m^3). The results show that 30 kg/m^3 might be the maximum density which RAS can af ford in China. The stocking densities under 30 kg/m^3 have no ef fect on mortality of Atlantic salmon reared in RAS. However, the speci?c growth rate(SGR), ?nal weight and weight gain in the high density group were signi?cantly lower than the lower density groups and middle density groups. Moreover, feed conversion rate(FCR) had a negative correlation with density. Plasma hormone T_3 and GH showed signi?cant decrease with the increase of the stocking density of the experiment. Furthermore, thyroid hormone(T 3), GH(growth hormone) activities were decreased with stocking density increase. However, plasma cortisol, GOT(glutamic oxalacetic transaminase) and GPT(glutamic pyruvic transaminase) activities were increase with stocking density increase. And the stocking density has no ef fects on plasma lysozyme of Atlantic salmon reared in RAS. These investigations would also help devise effcient ways to rear adult Atlantic salmon in China and may, in a way, help spread salmon mariculture in China.     

Microbial diversity in the sediments of the southern Mariana Trench

Microbial diversity in the abyssal sediments beneath the seafloor of 30,94,and 151cm near the southern end of the Mariana Trench was analyzed in the Illumina HiSeq 2500 platform.Results show that the microbial populations were dominated by bacteria but merely no archaea were identifi ed at the three depths.In the bacterial community,Proteobacteria and Firmicutes dominated the total taxon tags,followed by Bacteroidetes,Actinobacteria,Planctomycetes,Cyanobacteria,and Chloroflexi,which together account for over 99%of the total population.Similar to that in the seawater in the trench,the operational taxonomic units(OTUs)belonging to Gammaproteobacteria from the sediment samples showed high abundance.However,common bacterial OTUs in the water of the trench including Nitrospirae and Marinimicrobia were hardly found in the sediments from the southern Mariana Trench or the hadal region.Therefore,this study documented for the first time the compositions of microbial diversity in the trench sediments,revealed the difference in microbial diversity in water and sediment of the trench and will enrich the knowledge on the microbial diversity in the abyssal areas.     

银河系铝元素丰度研究

恒星的Al元素丰度可以为探索星团和星系的化学演化提供重要线索.通过系统分析银河系薄盘、厚盘、核球、银晕以及M4、M5等球状星团中恒星的[Al/Fe]随恒星金属丰度[Fe/H]的变化趋势,得出银河系薄盘、厚盘和核球恒星的[Al/Fe]随着[Fe/H]的增加而缓慢下降,而球状星团M4和M5恒星的[Al/Fe]随[Fe/H]增加没有下降趋势,这暗示Ia超新星对M4和M5恒星元素丰度的贡献比较小.详细研究了银河系恒星[Al/Fe]与[Mg/Fe]、[Na/Fe]的相关性,结果表明银河系场星的[Al/Fe]与[Mg/Fe]正相关,但在球状星团M4和M5恒星中未见此相关性;银河系盘星及M4和M5等球状星团恒星的[Al/Fe]与[Na/Fe]都存在正相关.     

Multi-band Solar Full-disk Extreme Ultraviolet Imager

Solar Extreme Ultraviolet (EUV) imaging observation is an important measure for the researches of solar activities and coronal plasma physics. But the traditional EUV imager and spectrograph can hardly achieve simultaneously the high spectral resolution and wide field-of-view of solar imaging. This paper has designed a new type of solar EUV multi-band imager, by adopting a kind of slitless grating and grazing incidence structure, it can realize the solar full-disk imaging of high spectral and spatial resolution. The field-of-view of the imager can be as broad as 47′. The spectral resolution is 2×10^?3nm per pixel, and the spatial resolution is 1.4′ per pixel. The temporal resolution of the solar full-disk is better than 60 s. The analysis of the solar full-disk spectral image and system response shows that the imager can observe the morphological evolutions of various solar activities, and can provide more comprehensive data for the researches of solar physics and space weather forecast.     

无人机倾斜摄影三维模型在城市雨洪风险评估中的应用

研究城市雨洪风险问题,对提高城市洪涝灾害监测、预报的准确性,以及促进城市防洪决策制定具有重要的意义。鉴于高精度的城市三维模型可以提供丰富地理信息,便于准确分析淹没情况,本文针对当前城市洪涝模型对地形数据的高敏感性,且雨洪风险评估研究的准确性受限于地形数据精度的问题,提出利用无人机倾斜摄影测量技术重建高精度实景三维模型,并结合GIS的空间分析功能,以淹没深度为关键指标进行研究区的雨洪风险评估。通过提取不同重现期下研究区的淹没深度信息,进行可视化渲染实现三维淹没分析,可以直观地看到研究区的淹没情况,作为暴雨内涝风险管理依据,同时对城市规划布局有一定的参考价值。     

多源高分辨率DOM批量快速制作方法研究

随着遥感数据在自然资源调查中的广泛应用,对多源高分辨率遥感影像“一张图”批量快速制作有了更高的需求。本文以广西壮族自治区北海市银海区作为试验区,利用Pixel Engine软件的“RS+GIS+Photoshop”算法,首先,针对多源高分辨率遥感卫星数据特点,制定相应的数据处理流程,自动化制作单景DOM;然后,以县级辖区为单位,批量快速制作县级辖区DOM;最后,从制作精度和速度两个方面,将该方法制作得到的DOM成果与人工处理成果进行对比,分析该方法的可行性,提出了一种快速、有效的多源高分辨率DOM制作方法。     

基于EMD方法的地心运动时间序列分析

针对时间序列混有的高频信息会影响地心运动规律分析的问题,采用网平移法对IGS提供的GNSS周解进行解算,得到2007-2017年地心运动时间序列,对其进行分解重构,剔除高频项,并利用重构时序对地心运动规律作进一步分析探讨。结果表明：本文解算的地心运动在T_x、T_y和T_z方向的精度均为毫米级。EMD方法重构的时序保留了原序列的基本信息,且抑制了高频项的影响,提高了周期贡献率,3个方向的贡献率分别提高了12.3%、16.7%及6.3%。通过分析重构后的时序发现,周年项振幅为各周期对应振幅的最大值,分别为2.32、1.89和2.07 mm;T_y和T_z方向长期变化趋势较T_x更为明显,分别为0.13和-0.27 mm/a;半年项较小,且在T_x和T_y方向上具有时变性。此外,还发现了一些其他较小的年际变化。     

多类重力场模型的精度分析

分析国际公布的EGM2008、GECO和EIGEN-6C4等超高阶重力场模型及GOCO03S、GOCONSGCF2DIRR5和GOCONSGCF2TIMR5等低阶重力场模型的内符合精度。利用实测的GNSS/水准数据对各模型进行外符合精度的检核。分析6个模型在不同阶次组合的精度,进而选取可靠的截断阶次确定组合重力场模型。计算结果表明:EGM2008、GECO、EIGEN-6C4及DIRR5四个重力场模型的阶方差均保持在mm级,而GOCO03S在191阶之后的精度达到dm级,TIMR5模型在228阶之后的精度达到dm级;6个重力场模型中,EIGEN-6C4模型的累计阶方差最小;EGM2008、GECO模型的互差阶方差在高频部分呈现差异,而在超高阶部分两种模型的互差阶方差符合性好;与EGM2008模型相比,其组合重力场模型高程异常精度最优可达0.063 m,精度提升幅度为15%,与GECO模型相比,其组合重力场模型高程异常精度最优可达0.060 m,精度提升幅度为23%,与EIGEN-6C4模型相比,其对应的组合重力场模型高程异常精度最优可达0.064 m,精度提升幅度为18%,因此,组合重力场模型能提高重力场模型高程异常的精度。     

重庆直辖以来乡村人居环境可持续发展力及其时空分异研究

乡村人居环境是一复杂巨系统,其可持续发展力是各子系统间物质、信息与能量相互流通与交换的结果,本文从经济发展、生产生活、生态环境3个子系统入手构建乡村人居环境可持续发展力的评价指标体系,以1997—2015年重庆市37个区县的面板数据为数据源,运用发展水平(衡量乡村人居环境可持续发展态势)、发展效率(反映乡村人居环境发展趋向可持续的快慢程度)和协调指数(反映各子系统发展水平均衡程度)构建乡村人居环境可持续发展力测度模型,分析了乡村人居环境可持续力并探究其时空分异特征,为因地制宜践行《农村人居环境整治三年行动方案》提供策略支持。结果表明：1997—2015年,乡村人居环境可持续发展力时序上总体态势向好,其中发展水平逐步上升,发展效率波动剧烈,协调性稳步提高,各子系统间可持续发展力差异性较大;乡村人居环境可持续发展力在空间上总体呈现西高东低、“中心-边缘”的分异格局,区县间差异性明显,其中经济发展子系统呈“多级核心-外围”辐射圈层式差异化增长格局、生产生活子系统呈自西向东扩散式增长格局,生态环境子系统总体上先降后升,呈波浪式不均衡增长格局;从政府“制导引导”、城乡“双轮”联动、“点-极-核”整治模式等方面提出了相关整治策略。