Resolving mechanisms of toxicity while pursuing ecotoxicological relevance?

In this age of modern biology, aquatic toxicological research has pursued mechanisms of action of toxicants. This has provided potential tools for ecotoxicologic investigations. However, problems of biocomplexity and issues at higher levels of biological organization remain a challenge. In the 1980s and 1990s and continuing to a lesser extent today, organisms residing in highly contaminated field sites or exposed in the laboratory to calibrated concentrations of individual compounds were carefully analyzed for their responses to priority pollutants. Correlation of biochemical and structural analyses in cultured cells and tissues, as well as the in vivo exposures led to the production and application of biomarkers of exposure and effect and to our awareness of genotoxicity and its chronic manifestations, such as neoplasms, in wild fishes. To gain acceptance of these findings in the greater environmental toxicology community, “validation of the model” versus other, better-established often rodent models, was necessary and became a major focus. Resultant biomarkers were applied to heavily contaminated and reference field sites as part of effects assessment and with investigations following large-scale disasters such as oil spills or industrial accidents.

Over the past 15 years, in the laboratory, small aquarium fish models such as medaka (Oryzias latipes), zebrafish (Danio rerio), platyfish (Xiphophorus species), fathead minnow (Pimephales promelas), and sheepshead minnow (Cyprinodon variegatus) were increasingly used establishing mechanisms of toxicants. Today, the same organisms provide reliable information at higher levels of biological organization relevant to ecotoxicology. We review studies resolving mechanisms of toxicity and discuss ways to address biocomplexity, mixtures of contaminants, and the need to relate individual level responses to populations and communities.     

An Improved Approach for Parameterizing Surface-Layer Turbulent Transfer Coefficients in Numerical Models

Based on classic iterative computation results, new equations to calculate the surface turbulent transfer coefficients are proposed, which allow for large ratios of the momentum and heat roughness lengths. Compared to the Launiainen scheme, our proposed scheme generates results closer to classical iterative computations. Under unstable stratification, the relative error in the Launiainen scheme increases linearly with increasing instability, even exceeding 15%, while the relative error of the present scheme is always less than 8.5%. Under stable stratification, the Launiainen scheme uses two equations, one for 0 < Ri _B ≤ 0.08 and another for 0.08 < Ri _B ≤ 0.2, and does not consider the condition that Ri _B > 0.2, while its relative errors in the region 0 < Ri _B ≤ 0.2 exceed 31 and 24% for momentum and heat transfer coefficients, respectively. In contrast, the present scheme uses only one equation for 0 < Ri _B ≤ 0.2 and another equation for Ri _B > 0.2, and the relative error of the present scheme is always less than 14%.     

Genetic mechanism and failure process of the Mogangling seismic landslide

This paper presents a case study on the Mogangling landslide and its characteristics and geological mechanism. The Mogangling landslide is a giant rock landslide located at the intersection of Dadu river and Moxi river. It is a landslide triggered by an earthquake with large magnitude that occurred in 18th century. Based on detailed site investigation, it shows the Mogangling landslide developed in the Kangding complex strata, composed of completely decomposed aggregates of massive-block stone, debris and soil with some gravels, pebbles and sand layer found distributed in front of the landslide. The control factor of the deformation of this landslide is the combined effect of Detuo fault which is located under the slope, and the regional stress formed along structural planes as well as the free surfaces formed by river cutting. Therefore, when the Kangding-Moxi earthquake (Ms =7.7) occurred on 1st June, 1786, due to seismic shaking, topographic amplification effects and back slope effects, the Mogangling landslide occurred. The Dadu River is the most important river for hydropower development in China; large-scale seismic landslides along the Dadu River are the most important geological issue during the construction of hydropower stations. Therefore, this research is important from the point of view of economic and social benefits.     

Inverse Analysis of Deep Excavation Using Differential Evolution Algorithm

This paper presents the applications of the differential evolution (DE) algorithm in back analysis of soil parameters for deep excavation problems. A computer code, named Python‐based DE, is developed and incorporated into the commercial finite element software ABAQUS, with a parallel computing technique to run an FE analysis for all trail vectors of one generation in DE in multiple cores of a cluster, which dramatically reduces the computational time. A synthetic case and a well‐instrumented real case, that is, the Taipei National Enterprise Center (TNEC) project, are used to demonstrate the capability of the proposed back‐analysis procedure. Results show that multiple soil parameters are well identified by back analysis using a DE optimization algorithm for highly nonlinear problems. For the synthetic excavation case, the back‐analyzed parameters are basically identical to the input parameters that are used to generate synthetic response of wall deflection. For the TNEC case with a total of nine parameters to be back analyzed, the relative errors of wall deflection for the last three stages are 2.2, 1.1, and 1.0%, respectively. Robustness of the back‐estimated parameters is further illustrated by a forward prediction. The wall deflection in the subsequent stages can be satisfactorily predicted using the back‐analyzed soil parameters at early stages. Copyright © 2014 John Wiley & Sons, Ltd.     

福建明溪上地幔热结构及流变学特征

通过对采自福建明溪的幔源包体样品的详细研究,建立了该区上地幔的地温线,探讨其流变学特征。所获地温线高于大洋地温线,但稍低于中国东部和澳大利亚东南部地温线。由该地温线推导的壳幔边界为３８ｋｍ左右,但尖晶石二辉橄榄岩在３２ｋｍ左右即已开始出现,表明存在上地幔物质的底侵作用。同样,尖晶石二辉橄榄岩和石榴子石二辉橄榄岩包体平衡温度有所重叠,表明两者不是截然分开,其间存在有５￣１０ｋｍ的过渡带。包体的变形特     

Mineralogical, chemical, and crystallographic properties of supergene jarosite-group minerals from the Xitieshan Pb-Zn sulfide deposit, northern Tibetan Plateau, China

Supergene jarosite-group minerals are widespread in weathering profiles overlying Pb-Zn sulfide ores at Xitieshan, northern Tibetan Plateau, China. They consist predominantly of K-deficient natrojarosite, with lesser amounts of K-rich natrojarosite and plumbojarosite. Electron microprobe (EMP) analyses, scanning electron microcopy (SEM) investigation, and X-ray mapping reveal that the jarosite-group minerals are characterized by spectacular oscillatory zoning composed of alternating growth bands of K-deficient and K-bearing natrojarosite (K₂O >1 wt.%). Plumbojarosite, whenever present, occurs as an overgrowth in the outermost bands, and its composition can be best represented by K_0.29Na_0.19Pb_0.31Fe_2.66Al_0.22(SO₄)_1.65(PO₄)_0.31(AsO₄)_0.04(OH)_7.37. The substitution of monovalent for divalent cations at the A site of plumbojarosite is charge balanced by the substitution of five-valent for six-valent anions in XO₄ at the X site. Thermogravimetric analysis (TGA) of representative samples reveal mass losses of 11.46 wt.% at 446.6 °C and 21.42 wt.% at 683.4 °C due to dehydroxylation and desulfidation, respectively. TGA data also indicate that the natrojarosite structure collapses at 446.6 °C, resulting in the formation of NaFe(SO₄)₂ and minor hematite. The decomposition products of NaFe(SO₄)₂ are hematite and Na₂SO₄. Powder X-ray diffraction (XRD) analyses show that the jarosite-group minerals have mean unit-cell parameters of a?=?7.315 Å and c?=?016.598 Å. XRD and EMP data support the view that substitutions of Na for K in the A site and full Fe occupancy in the B site can considerably decrease the unit-cell parameter c, but only slightly increase a. The results from this study suggest that the observed oscillatory zoning of jarosite-group minerals at Xitieshan resulted mainly from substitutions of K for Na at the A site and P for S at the X site.     

Changes of Warmer Winter and Winter Temperature over China During 1956-2005

 A reasonable warmer winter index (IWWI) in the framework of the three equiprobability categories (i.e. warmer, normal and colder categories) is proposed based on the winter temperature data observed at 565 stations in China during 1956-2005, where IWWI is defined as the ratio of the station number of warmer category over the total number of stations. The results suggest that the trend of IWWI was consistent with that of the winter temperature on decadal time scale, and their rates of change were 10%/10 a and 0.4 ℃/10 a, respectively. It is found that only 13 warmer winter events in total were detected by IWWI over the past 50 years, and 85% of them occurred after 1986.     

Precipitation variability during the past 400?years in the Xiaolong Mountain (central China) inferred from tree rings

We developed the first tree-ring chronology, based on 73 cores from 29 Pinus tabulaeformis trees, for the Xiaolong Mountain area of central China, a region at the boundary of the Asian summer monsoon. This chronology exhibits significant (at 0.01 level) positive correlations with precipitation in May and June, and negative correlations with temperature in May, June and July. Highest linear correlation is observed between tree growth and the seasonalized (April–July) precipitation, suggesting that tree rings tend to integrate the monthly precipitation signals. Accordingly, the April–July total precipitation was reconstructed back to 1629 using these tree rings, explaining 44.7?% of the instrumental variance. A severe drought occurred in the area during the 1630s–1640s, which may be related to the weakened Asian summer monsoon caused by a low land-sea thermal gradient. The dry epoch during the 1920s–1930s and since the late 1970s may be explained by the strengthened Hadley circulation in a warmer climate. The dry (wet) epochs of the 1920s–1930s (the 1750s and 1950s) occurred during the warm (cold) phases of the El Ni?o-Southern Oscillation and the Pacific Decadal Oscillation that are often associated with weakened (strengthened) East Asian summer monsoon. These relationships indicate significant teleconnections operating over the past centuries in central China related to large-scale synoptic features.     

Degradation of native wheat straw lignin by Streptomyces viridosporus T7A

Lignin is one of the major contributing factors toward the recalcitrance of lignocellulosic biomass. Understanding the process of lignin degradation in natural biological processes will provide useful information to develop novel biomass conversion technologies. Functional group changes in the lignin entities during the process may contribute to the cellulose degradation (utilization) by the microorganisms. In this study, compositional and advanced Fourier transform infrared, pyrolysis gas chromatography/mass spectrometry and ¹³C cross polarization/magic angle spinning nuclear magnetic resonance analysis were performed to explore the mechanism of biodegradation of wheat straw by Streptomyces viridosporus T7A. The results indicated that S. viridosporus T7A removed lignin and hemicelluloses as indicated by the increased carbohydrate/lignin ratio. Significant modification of carbonyl and methoxyl groups in the complex lignin structure was also evident. Most importantly, the quantitative results showed that lignin degradation was featured by deduction of guaiacyl unit. The results provide new insight for understanding lignin degradation by bacteria.     

考虑土-结构相互作用的振动台实时子结构试验仿真分析

本文基于状态空间方程进行了实时子结构试验的初步探索,提出了一种新的实时子结构试验方法。通过simulink仿真发现,这种方法能很好地再现整体分析的结构反应。最后,对考虑土-结构相互作用的振动台实时子结构试验进行了仿真分析。