Isolation and pharmacological activities of bromophenols from Rhodomela confervoides

Four bromophenols were isolated from the extract of marine red alga,Rhodomela confervoides by column chromatography and HPLC methods. By means of spectroscopic methods inclding IR, MS, 1D, and 2D-NMR techniques, their structures were elucidated as (1) 3-bromo-4,5-dihydroxy benzoic acid methyl ester; (2) bis (2,3-dibromo-4,5-dihydroxybenzyl) ether; (3) 3,4-dibromo-5-(methoxymethyl)-1,2-benzenediol and (4) 3-bromo-4,5-dihydroxy-benzaldehyde. Compound 1 was first isolated from the algae in nature, and 1, 4 were found to have selective cytotoxic activities against KB, Bel 7402 and A549 cells, 2 showed powerful antibacterial activities againstStaphylococcus aurens andPseudomonas aeruginosa. Supported by National “863” Program (No. 2004AA625030, 2001AA620503), Quingdao marine sciences project (No. 04-2-NN-26) and Key Knowledge Innovative Project of the Chinese Academy of Sciences (KZCX3-SW-215).     

The Early Pleistocene Praetiglian and Ludhamian pollen stages in the North Sea Basin and their relationship to the marine isotope record

In this paper, the currently accepted correlation of the Early Pleistocene Ludhamian stage of England with the Tiglian‐A sub‐stage of the Netherlands is challenged. Recent investigations of Early Pleistocene marine North Sea deposits from a borehole near Noordwijk (the Netherlands) yielded evidence from molluscs, dinoflagellate cysts and sporomorphs for an alternation of warm‐temperate and arctic intervals within the Praetiglian and Tiglian stages. Marine equivalents of the terrestrial‐based pollen sub‐stages Tiglian A and B have been recognised in the upper part of the sequence. A Praetiglian age can be assigned to the lower part of the sequence on the basis of mollusc analysis. Within the Praetiglian, an alternation of warm and cold phases has been recognised from both the dinoflagellate cyst and molluscan records. Three cold phases within the Praetiglian are tentatively correlated with marine isotope stages (MIS) 96–100. The molluscan assemblages provide evidence for climate forcing of the sea level: highest sea levels are reached in the warm‐temperate intervals. Within the Praetiglian, an interval with an acme zone of the dinoflagellate cyst Impagidinium multiplexum, is correlated with the Ludhamian and tentatively linked to MIS 97 and/or MIS 96. The cold molluscan assemblages from the Noordwijk borehole include an acme zone of Megayoldia thraciaeformis, the first and only occurrence of this North Pacific bivalve in the North Sea Basin. Copyright © 2006 John Wiley & Sons, Ltd.     

Design of stable drainage networks in upland forestry plantations

Erosion of man-made, forestry drainage channels occurs when the plough cuts through the surface peat layer into the underlying erodible mineral soil. A procedure is developed, based on hydraulic considerations, which will allow the drainage engineer to design stable drainage networks in upland forestry plantations. An example design chart is given for an erodible sandy loam type soil.     

The variability of Mercury's exosphere by particle and radiation induced surface release processes

Mercury's close orbit around the Sun, its weak intrinsic magnetic field and the absence of an atmosphere (P_surface<1×10⁻⁸ Pa) results in a strong direct exposure of the surface to energetic ions, electrons and UV radiation. Thermal processes and particle-surface-collisions dominate the surface interaction processes leading to surface chemistry and physics, including the formation of an exosphere (N?10¹⁴ cm⁻²) in which gravity is the dominant force affecting the trajectories of exospheric atoms. NASA's Mariner 10 spacecraft observed the existence of H, He, and O in Mercury's exosphere. In addition, the volatile components Na, K, and Ca have been observed by ground based instrumentation in the exosphere. We study the efficiency of several particle surface release processes by calculating stopping cross-sections, sputter yields and exospheric source rates. Our study indicates surface sputter yields for Na between values of about 0.27 and 0.35 in an energy range from 500 eV up to 2 keV if Na⁺ ions are the sputter agents, and about 0.037 and 0.082 at an energy range between 500 eV up to 2 keV when H⁺ are the sputter agents and a surface binding energy of about 2 eV to 2.65 eV. The sputter yields for Ca are about 0.032 to 0.06 and for K atoms between 0.054 to 0.1 in the same energy range. We found a sputter yield for O atoms between 0.025 and 0.04 for a particle energy range between 500 eV up to 2 keV protons. By taking the average solar wind proton surface flux at the open magnetic field line area of about 4×10⁸ cm⁻² s⁻¹ calculated by Massetti et al. (2003, Icarus, in press) the resulting average sputtering flux for O is about 0.8-1.0×10⁷ cm⁻² s⁻¹ and for Na approximately 1.3-1.6×10⁵ cm⁻² s⁻¹ depending on the assumed Na binding energies, regolith content, sputtering agents and solar activity. By using lunar regolith values for K we obtain a sputtering flux of about 1.0-1.4×10⁴ cm⁻² s⁻¹. By taking an average open magnetic field line area of about 2.8×10¹⁶ cm² modelled by Massetti et al. (2003, Icarus, in press) we derive an average surface sputter rate for Na of about 4.2×10²¹ s⁻¹ and for O of about 2.5×10²³ s⁻¹. The particle sputter rate for K atoms is about 3.0×10²⁰ s⁻¹ assuming lunar regolith composition for K. The sputter rates depend on the particle content in the regolith and the open magnetic field line area on Mercury's surface. Further, the surface layer could be depleted in alkali. A UV model has been developed to yield the surface UV irradiance at any time and latitude over a Mercury year. Seasonal and diurnal variations are calculated, and Photon Stimulated Desorption (PSD) fluxes along Mercury's orbit are evaluated. A solar UV hotspot is created towards perihelion, with significant average PSD particle release rates and Na fluxes of about 3.0×10⁶ cm⁻² s⁻¹. The average source rates for Na particles released by PSD are about 1×10²⁴ s⁻¹. By using the laboratory obtained data of Madey et al. (1998, J. Geophys. Res. 103, 5873-5887) for the calculation of the PSD flux of K atoms we get fluxes in the order of about 10⁴ cm⁻² s⁻¹ along Mercury's orbit. However, these values may be to high since they are based on idealized smooth surface conditions in the laboratory and do not include the roughness and porosity of Mercury's regolith. Further, the lack of an ionosphere and Mercury's small, temporally and spatially highly variable magnetosphere can result in a large and rapid increase of exospheric particles, especially Na in Mercury's exosphere. Our study suggests that the average total source rates for the exosphere from solar particle and radiation induced surface processes during quiet solar conditions may be of the same order as particles produced by micrometeoroid vaporization. We also discuss the capability of in situ measurements of Mercury's highly variable particle environment by the proposed NPA-SERENA instrument package on board ESA's BepiColombo Mercury Planetary Orbiter (MPO).