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991.
992.
993.
在对新疆1973年以来年度地震预测情况进行综合研究基础上,重点分析了乌恰-喀什周围地区年度预测的阶段性特点,并对这一地区1900年以来M≥6地震和1972-2008年M≥5.5地震活动特征进行了的研究.认为对该区域地震活动规律性特点认识不足,没有遵循本地区地震活动的基本规律对地震趋势进行客观判断,是造成地震危险区预测效果较差的主要原因.依据地震活跃与间歇的特点认为2008年底开始乌恰-喀什周围地区将进入一个新的活跃时段,这一地区可能仍将继续被划定为年度强地震危险区. 相似文献
994.
The ecological tidal model simulates the cycling of carbon, nitrogen, phosphate, and silicate and describes the tidal, diurnal,
and annual dynamics of the back barrier area of the island Spiekeroog in the German Bight. The region is characterized by
strong tidal currents and extensive tidal flats. It is strongly influenced by the conditions in the southern part of the German
Bight. This model study investigates the dependence of the model behavior on the boundary conditions and the forcing. The
effect of short- and long-term sea level rise on nutrient and plankton dynamics is analyzed. As the model is set up as semi-Lagrangian
with only a coarse approximation of the hydrodynamics, the seasonal and intratidal variability in the biogeochemical cycling
can only be reproduced qualitatively. By varying the boundary conditions, the intrinsic dynamics of the back barrier area
can be separated from boundary condition effects. This study shows that any agreement between model results and field data
cannot be expected without correct boundary conditions. The seasonal variability is of major importance, while higher-frequency
variability only plays a minor role. 相似文献
995.
996.
澳门海洋空间资源利用研究——澳门的填海造地工程 总被引:4,自引:0,他引:4
澳门原系海中孤岛,由于利用了自然条件,进行填海造地工程,使孤岛相连,土地面积扩大,城市发展,交通改善,经济增长,成为利用海洋空间资源的典型地区。文章论述了澳门有利于填海工程实施的自然条件,海洋空间利用的发展过程,及填海造地工程的巨大作用和深远意义。 相似文献
997.
资源型城市可持续发展评价指标体系研究——以攀枝花为例 总被引:19,自引:0,他引:19
可持续发展指标是用以反映和评价可持续发展实践结果的测试手段。从经济发展转向可持续发展是人类认识自己、合理地发展自身的要本性转变。文章针对资源型城市目前发展面临的选择,为其有效地实施可持续发展战略和保证资源的可持续利用,建立的可持续发展评价体系,合硎骨意识、有监测地实施可持续发展战略。 相似文献
998.
D R Livingstone C L Mitchelmore S C O'Hara P Lemaire J Sturve L F?rlin 《Marine environmental research》2000,50(1-5):57-60
The present study investigated the proposed involvement of contaminant-stimulated reactive oxygen species (ROS) production in disease processes in fish. NAD(P)H-dependent ROS production of subcellular fractions was determined by the iron/EDTA-mediated oxidation of 2-keto-4-methiolbutyric acid. Hepatic cytosolic NADPH-dependent and microsomal NAD(P)H-dependent ROS production were increased 51-160% (P < 0.05) in rainbow trout (Oncorhynchus mykiss) 15 weeks after a single i.p. injection of polychlorobiphenyl (PCB) (100 mg Clophen A50 kg-1 wet wt.). Hepatic microsomal NADH-dependent ROS production was 114% higher in perch (Perca fluviatilis) from PCB-contaminated Lake J?rnsj?n compared to clean Lake V?nern, Sweden. Hepatic mitochondrial NADH-dependent, cytosolic NADH-dependent and microsomal NADPH-dependent ROS production were variously elevated up to 160% in flounder (Platichthys flesus) at various sites along two pollution transects near to the ports of Rotterdam and Amsterdam, Netherlands. Overall the data indicate increased potential for ROS production in liver of fish exposed to field pollution, and support the hypothesis of oxidative stress as a mechanism of contaminant-mediated disease in fish. 相似文献
999.
DNA from five tumors, three other-injured livers and two normal liver tissue samples from the European flounder were analyzed for mutations in exons 5-8 of the tumor suppressor gene p53 and at codons 12, 13 and 61 of Ha- and Ki-ras proto-oncogenes. No tumor-specific mutations were identified by direct sequencing and single-strand conformation polymorphism of these genes. A number of silent polymorphisms were noted in p53. In addition to a need for more extensive analyses of flounder liver tumor samples for ras or p53 mutations, other cancer-related genes should be investigated. 相似文献
1000.
Metallothioneins (MTs) are small, cysteine-rich proteins which detoxify xenobiotic metals such as cadmium (Cd) and mercury (Hg). In crustaceans and mammals they consist of two independent domains which are folded around metal-thiolate clusters. MT clusters of different origins, exhibiting distinct, highly conserved cysteine positions on their sequences, show differences in metal-cysteine coordination and reactivity. Lobster-MT, containing two Cd3 beta domains, is an important model for structure-function relationships among the clusters. The influence of (1) the position of the cysteine residues and (2) steric and electrostatic effects of neighboring amino acids on the folding and stability of MT cluster were investigated. Thus, the native lobster beta C and beta N domains (each having nine cysteines and binding three M2+ ions) and a modified domain Cd3 beta C-->N, in which the cysteines of the C-terminal domain were relocated to match the positions of those in the N-terminal domain, were chemically prepared and characterized. The synthetic native domains (Cd3 beta C and Cd3 beta N) were found to exhibit spectroscopic properties, metal-binding affinities and kinetic reactivity similar to the holo-protein. However, the modified Cd3 beta C-->N domain was unusually reactive and in the presence of Chelex, metal chelation resin, aggregated to a Cd5(beta C-->N)2 dimer, which exhibited unusual structure as observed by its 113Cd-nuclear magnetic resonance. These differences in structure and reactivity demonstrated that the requirements for formation of a stable Cd3S9 beta-cluster are more stringent than simply the sequential positions of the cysteines along the peptide chain and must include interactions involving neighboring, noncysteine amino acids. 相似文献