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151.
Polar bears bioaccumulate lipophilic pollutants, including polychlorinated biphenyls (PCBs), into their bodies from their exclusive diet of marine organisms. Hydroxylated PCB metabolites (OH-PCBs) have been found in plasma, presumably due to CYP-dependent biotransformation of PCBs in liver. Little is known about the phase 2 metabolism of hydroxylated xenobiotics in polar bears. The objective of this study was to examine UDP-glucuronosyltransferase (UGT) activity with OH-PCBs and a hydroxylated polycyclic aromatic hydrocarbon, 3-hydroxy-benzo(a)pyrene (3-OH-BaP), in polar bear liver. Samples of frozen polar bear liver were used to prepare microsomes. UGT activity with 3-OH-BaP in Brij-treated microsomes, measured by a fluorescence assay, was readily measurable with protein concentrations in assay tubes of up to 10 g/ml, but dropped off very sharply at higher protein concentrations. The apparent Km for 3-OH-BaP was 1.71 +/- 0.04 microM, and Vmax 1.26 +/- 0.16 nmol/min/mg protein (mean +/- SD, n=3). UGT activities with a model tetrachloro-OH-PCB (4'-OH-CB72) and a model hexachloro-OH-PCB (4'-OH-CB159) were assayed with [14-C]-UDPGA and separation of the [14-C]-glucuronide by ion-pair extraction and thin-layer chromatography. [14-C]-glucuronide conjugates were readily formed by polar bear liver microsomes in the absence of added substrate, apparently from contaminants present in liver. This phenomenon was not observed using hepatic microsomes from laboratory-held catfish. Glucuronidation efficiency was much higher with 4'-OH-CB72 (Km 7.3 microM; Vmax 1.55 nmol/min/mg) than 4'-OH-CB159 (Km 16.1 microM; Vmax 0.46 nmol/min/mg). The identities of the aglycones present in polar bear liver are not known, but could include OH-PCBs or hydroxylated metabolites of other persistent organic pollutants. This study demonstrates that UGT with high activity for 3-OH-BaP and other substrates is present in polar bear liver. 相似文献
152.
基于EOF分析对南海西北海域水体光谱特性的研究 总被引:1,自引:0,他引:1
This study presents an analysis of the spectral characteristics of remote sensing reflectance(R_(rs)) in northwestern South China Sea based on the in situ optical and water quality data for August 2018.R_(rs)was initially divided into four classes,classes A to D,using the max-classification algorithm,and the spectral properties of whole R_(rs) were characterized using the empirical orthogonal function(EOF) analysis.Subsequently,the dominant factors in each EOF mode were determined.The results indicated that more than 95% of the variances of R_(rs) are partly driven by the back-scattering characteristics of the suspended matter.The initial two EOF modes were well correlated with the total suspended matter and back-scattering coefficient.Furthermore,the first EOF modes of the four classes of R_(rs)(A-D R_(rs)-EOF_1) significantly contributed to the total variances of each R_(rs) class.In addition,the correlation coefficients between the amplitude factors of class A-D R_(rs)-EOF_1 and the variances of the relevant water quality and optical parameters were better than those of the unclassified ones.The spectral shape of class AR_(rs)-EOF_1 was governed by the absorption characteristic of chlorophyll a and colored dissolved organic matter(CDOM).The spectral shape of class B R_(rs)-EOF_1 was governed by the absorption characteristic of CDOM since it exhibited a high correlation with the absorption coefficient of CDOM(a_g(λ)),whereas the spectral shape of class C R_(rs)-EOF_1 was governed by the back-scattering characteristics but not affected by the suspended matter.The spectral shape of class D R_(rs)-EOF_1 exhibited a relatively good correlation with all the water quality parameters,which played a significant role in deciding its spectral shape. 相似文献
153.
Available measurements of foundation behaviour of the 13 concrete gravity platforms installed in the North Sea in the years 1973–1978 are presented. The measurements cover both the installation phase and the early part of the operation period. For the installation phase, measurements of dowel and skirt penetration resistance, base contact stresses, tilt, piping and erosion, are presented. For the operation period, the presentation includes measurements of settlements, pore water pressures, base contact stresses, permanent lateral displacements, cyclic displacements, dynamic behaviour and erosion. The measurements are used to back calculate soil properties and to evaluate the adequacy of the design procedures which have been used. The observations give valuable experience with respect to the foundation performance of offshore gravity platforms. 相似文献
154.
By using the NCEP/NCAR reanalysis data sets for 1951–2001, we study the characteristics of Pacific cyclones. It is shown that the northeast-southwest
direction is predominant in the displacements of cyclones in the North Pacific. We study the variability of the field of surface
atmospheric pressure in different phases of the Pacific decadal oscillation characterizing the temperature anomalies on the
surface of the ocean in the region bounded by 20 and 60°N. It is shown that the decadal variations of the North Atlantic Oscillation
supported by the large-scale anomalies of the Pacific decadal oscillation is the most important cause of natural decadal oscillations
in the European region. We study and evaluate the regional response to the Pacific decadal oscillation by using, as an example,
the analysis of variations of the discharge of European rivers.
__________
Translated from Morskoi Gidrofizicheskii Zhurnal, No. 4, pp. 13–23, July–August, 2007. 相似文献
155.
Calcareous nannoplankton from sediment trap samples collected at six sites in the Atlantic Ocean from 23° S to 73° N (cruise 20 of R/V Vityaz’ and cruise 33 and 34 of R/V Akademik Mstislav Keldysh). Those samples were studied with a scanning electron microscope. In the coastal and open-sea regions of the North and South Atlantic and in the subarctic region of the Norwegian Sea, the conditions are significantly different. In the shelf area of the Benguela upwelling, 11 species were recognized; some of them were agglutinated by diatoms and tintinnides or covered the surface of pellets. The Broken Spur and TAG pelagic areas of the North Atlantic contained up to 43 coccolith species. They included holococcoliths, large pelagic, and delicate easily soluble species distributed over the entire water column. The presence of coccoliths in the high-latitude area of the Norwegian Sea is related to their supply with the warmer North Atlantic waters. These assemblages are distinguished by a low species diversity and an enhancement of the coccolith solubility with the depth increase. 相似文献
156.
本文推导出σ坐标系斜压大气的准地转位涡方程,该方程形式与P坐标系的准地转位涡方程非常相似,但本质不同,本文还用WKB方法讨论了大地形坡度对斜压大气扰动发展的影响。指出:东西走向山脉的南坡有利于低层大气槽线呈西北-东南向的扰动发展,也有利于高层大气槽线呈东北-西南向的扰动发展 相似文献
157.
真鲷的营养需要及配合饲料的研究初报 总被引:8,自引:0,他引:8
本文综述了真鲷的营养需要,研究了不同植物蛋白源对真鲷生长的影响,并在此基础上设计了三种饲料配方,试验结果表明I号饲料配方的增长率最高。 相似文献
158.
Thesecondorderspectrumoftwo-dimensionalrandomwaves¥DingPingxing;SunFuandYuZhouwen(ReceivedJanuary15,1993;acceptedMay31,1993)A... 相似文献
159.
160.
This paper discusses some problems related to the development of systems of global monitoring of the sea surface temperature (SST). The characteristics of the operational SST data are considered and estimations of their accuracy are given. The applications of varoous models to the computation of SST in relation to the development of an oceanographic data assimilation system are reviewed briefly.Translated by Mikhail M. Trufanov. 相似文献