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231.
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233.
目的 探讨阿霉素性心肌病大鼠发生心律失常的发病机制。方法 健康wistar雄性大鼠20只,体重200g,适应周围环境1周后,随机将20只wistar雄性大鼠分为对照组(n=10)和阿霉素(ADR)组(n=10)。ADR组的大鼠在1周内进行3次腹腔注射ADR 2mg/kg;同时对照组则进行3次腹腔注射0.9%NaCl (2ml/kg),停药后让两组大鼠自由饮食4周。7周后对两组大鼠行心脏彩超检测,左心室舒张末径(LVEDd)与左心室收缩末期内径(LVESd)及左心室射血分数(LVEF),行VG染色观察各组大鼠心肌纤维化情况;扫描电镜染色观察左心室心肌细胞闰盘病理学变化;两组大鼠心肌结缔组织生长因子(CTGF)、转化生长因子β1(TGF-β1)、N型钙黏蛋白(N-cad)、桥粒芯糖蛋白(DSG2)表达应用ELISA法检测;采用Western blot法检测两组大鼠的心肌细胞Cx40 、Cx43、p-Cx43蛋白表达。结果 与对照组相比,阿霉素组大鼠明显出现心室重构,并易出现心律失常;电镜下观察ADR组大鼠心肌细胞闰盘破损严重,间隙增宽,VG染色显示ADR组大鼠病理积分明显高于对照组(P<0.05);ADR组大鼠相较于对照组大鼠心室肌中CTGF、TGF-β1的表达升高显著,N-cad、DSG2、Cx40、Cx43及p-Cx43的表达明显减低(P<0.05)。结论 ADR组大鼠可能由于心室肌细胞纤维化、闰盘结构受损、缝隙连接重构等原因导致心律失常。 相似文献
234.
Tracking embodied carbon flows in the Belt and Road regions 总被引:2,自引:1,他引:2
In the past few decades, economic globalization has driven rapid growth of cross-border trade and a new international division of labor, leading to increasing inter- country embodied carbon flows. Multi-region input-output (MRIO) analysis is used to identify embodied carbon flows between major world regions, including seven regions along the Belt and Road (BR), and the spatial distribution of production- and consumption-based carbon intensities. The results show that current embodied carbon flows are virtually all from BR regions to developed countries, with more than 95% of world net embodied carbon exports coming from BR regions. Consumption in the United States and European Union countries induce about 30% of the carbon emissions in most BR regions, indicating that the former bear a high proportion of consumers’ responsibility for the carbon emitted in the latter. For this reason, measuring environmental responsibilities from consumption rather than a production- based perspective is more equitable, while developing countries should be given a louder voice in the construction through dialogue and cooperation, in part in the context of the Belt and Road Initiative, of an inclusive global climate governance system. 相似文献
235.
不动产征收前后价值变化研究对于不动产征收主体博弈分析具有重要的意义,也为不动产征收补偿价格评估提供了理论支持。主要通过城乡不动产征收前后价值变化以及被征收人利益损害的分析,探讨了不同目的下的中国不动产征收主体博弈模型及行为选择。研究认为:(1)基于预期收益原则的不动产征收价格评估为不动产征收补偿与征收增值收益分配提供了理论依据;(2)基于公共目的性征收分析表明被征收人的权益保护很大程度上依赖于政府的角色定位,基于非公共目的性征收分析表明由于增值利益分配的零和博弈冲突以及政府的惯性强势思维,对现有政策体制不可避免地带来一系列冲突;(3)基于公共目的性划分的不动产征收与国家收购两种类型有利于区别制定不动产征收政策,从而促进土地资源的合理流动与优化配置。 相似文献
236.
Mathematical model of porous media dissolution coupled with two-phase flow is proposed. The model is based on the conception of dissolvable porous medium with deformable mass-variable porous skeleton. Model can be used for simulation of coupled chemo- and hydrogeomechanical processes which are difficult to examine experimentally. Acidizing of calcite oil reservoir is used as an example of the process. Water solution of hydrochloric acid and oil are two fluid phases of the model with several components. Dissolvable porous media is treated as deformable mass-variable solid phase. Change in mass of the solid phase is caused by hydrochloric acid dissolving the calcite part of the solid phase. Dissolution is supposed to be congruent; kinetics is governed by the Nernst law. Software for numerical solution of the model is developed. It uses AmgCL parallel library for high-performance computing in order to deal with large algebraic systems on the each time step of calculations. The library uses algebraic multigrid methods for preconditioning and parallel iterative solvers. NVidia CUDA framework is used as a backend to perform GPGPU calculations, because it proved to be faster than OpenCL framework on this problem. Numerical experiments on the basis of data set from real reservoirs are conducted with the developed software. Good correlation between field and calculated data is achieved. Numerical experiments for different configurations of heterogeneous layer are performed. Acidizing of layers with highly permeable conduit and with random distribution of permeability is modeled. 相似文献
237.
Capacity of soil loss control in the Loess Plateau based on soil erosion control degree 总被引:4,自引:0,他引:4
Haidong Gao Zhanbin Li Lianlian Jia Peng Li Guoce Xu Zongping Ren Guowei Pang Binhua Zhao 《地理学报(英文版)》2016,26(4):457-472
The capacity of soil and water conservation measures, defined as the maximum quantity of suitable soil and water conservation measures contained in a region, were determined for the Loess Plateau based on zones suitable for establishing terraced fields, forestland and grassland with the support of geographic information system (GIS) software. The minimum possible soil erosion modulus and actual soil erosion modulus in 2010 were calculated using the revised universal soil loss equation (RUSLE), and the ratio of the minimum possible soil erosion modulus under the capacity of soil and water conservation measures to the actual soil erosion modulus was defined as the soil erosion control degree. The control potential of soil erosion and water loss in the Loess Plateau was studied using this concept. Results showed that the actual soil erosion modulus was 3355 t?km-2?a-1, the minimum possible soil erosion modulus was 1921 t?km-2?a-1, and the soil erosion control degree was 0.57 (medium level) in the Loess Plateau in 2010. In terms of zoning, the control degree was relatively high in the river valley-plain area, soil-rocky mountainous area, and windy-sandy area, but relatively low in the soil-rocky hilly-forested area, hilly-gully area and plateau-gully area. The rate of erosion areas with a soil erosion modulus of less than 1000 t?km-2?a-1 increased from 50.48% to 57.71%, forest and grass coverage rose from 56.74% to 69.15%, rate of terraced fields increased from 4.36% to 19.03%, and per capita grain available rose from 418 kg?a-1 to 459 kg?a-1 under the capacity of soil and water conservation measures compared with actual conditions. These research results are of some guiding significance for soil and water loss control in the Loess Plateau. 相似文献
238.
239.
赵景波 《地理学报(英文版)》2004,14(2):242-250
On the basis of extensive survey to the Quatemary paleosols, soils and weathering layers in the vast northern China and the Loess Plateau, we found some unusually special phenomena of chemical components such as unsuccessive illuvium, twin illuviums, unusually thick illuvium and multi-illuviums etc. According to the analysis on the content of CaCO3 and the data of penetrating experiment, a new theory of illuvial depth or removal depth of CaCO3 in weathering and leaching belt was constructed, which indicates that the time of CaCO3 removing to the illuvial depth is very short,and the effect of time factor on illuvial depth can be ignored. The theory can be taken as a credible foundation for studying many geological and geographical problems in weathering and leaching belt.When the illuvial depth of CaCO3 iS bigger than the thickness of developing belt of soil or paleosol, it can be determined that the paleosol has turned into weathering crust. When the illuvial depth of CaCO3 is bigger than the thickness of paleosol, paleosol is leaching moderately acid soil. When two, three layers or unusually thick CaCO3 illuviums exist in the same weathering section or at the bottom of the same paleosol, there were two or more periods forming paleosol and corresponding climatic stages at that time. On the basis of the equation of relationship between mean annual rainfall (y) and illuvial depth of CaCO3 (x) (y = 305.5x 168.5) determined in the paper, mean annual precipitation during the development of paleosol can be calculated. 相似文献
240.
本文综合了国内外诸种有关资料,借鉴了国际上较通用的下垫面特征分类标准,也结合黑河地区下垫面的实际情况,对HEIFE试验区及其邻近地区的下垫面特征(包括地表特征、土壤特征及地形高度)进行归纳分类,形成了两种高分辨率(分别约为6km×6km及3km×3km)的下垫面特征的格点化资料,可供该地区地气相互作用研究用。 相似文献