Serum biochemical and cellular responses to experimental cupric ion challenge in mussels

Our intent has been to develop rapid and sensitive bioassay procedures for laboratory and field applications based on hemolymph factors in animals such as the bay mussel, Mytilus edulis. We found that mussel hemolymph could be easily and repeatedly sampled from individual animals in sufficient amounts to allow analyses for lysozyme, proteolytic activity, total protein and hemocyte counts. In static tests there seemed to be graded responses indicating release of increasing amounts of the above factors into the hemolymph in roughly direct proportion to Cu²⁺ concentration at lethal and sublethal levels. We interpreted this to be evidence for increased lysosomal and cellular disruption as cupric ion exposure was increased or prolonged. At the same time, Cu²⁺ concentrations in the mussel hemolymph increased up to an order of magnitude above ambient in the range of 26 to 267 ppb. We felt that this was evidence for the release of Cu-binding proteins into the mussel hemolymph. Simultaneously with the above events the serum granulocytes increased in numbers above control values by factors of 3 or 4 in response to copper challenge while macrophage (terminology of Moore & Lowe, 1977) counts, including controls, declined precipitously.     

RAGLAND,AN LL3.4 CHONDRITE FIND FROM NEW MEXICO

The Ragland, New Mexico chondrite was found in 1978, and consists of a single stone of 12.16 kg that broke into three pieces. The stone is moderately weathered and has a pronounced chondritic texture. Bulk composition favors an LL classification, and modal analysis and oxygen isotopic composition are consistent with this. The thermoluminescence sensitivity of 0.056 ± 0.020 normalized to Dhajala, compositional variability of olivine (mean Fa 18.3, σ = 10.1) and low-Ca pyroxene (mean Fs 14.6, σ = 6.7), and Ca concentrations in olivine indicate metamorphic subtype 3.4 ± 0.1. The isotopically heavy oxygen composition, which is characteristic of subtypes 3.0–3.1, may be a primary characteristic and not a result of weathering. Low concentrations of radiogenic ⁴⁰Ar and planetary ³⁶Ar suggest noble gas loss.     

Alkaline fluid circulation in ultramafic rocks and formation of nucleotide constituents: a hypothesis

Seawater is constantly circulating through oceanic basement as a low-temperature hydrothermal fluid (<150°C). In cases when ultramafic rocks are exposed to the fluids, for instance during the initial phase of subduction, ferromagnesian minerals are altered in contact with the water, leading to high pH and formation of secondary magnesium hydroxide, among other – brucite, that may scavenge borate and phosphate from seawater. The high pH may promote abiotic formation of pentoses, particularly ribose. Pentoses are stabilized by borate, since cyclic pentoses form a less reactive complex with borate. Analyses have shown that borate occupies the 2' and 3' positions of ribose, thus leaving the 5' position available for reactions like phosphorylation. The purine coding elements (adenine, in particular) of RNA may be formed in the same general hydrothermal environments of the seafloor.     

The fast dynamo in interstellar turbulence

The α effect and coefficient of eddy diffusivity are calculated for the magnetic field in a random flow with recovery. Such a flow loses its memory abruptly at random times that form a Poisson flow of events. Interstellar turbulence sustained by supernova outbursts is one physical realization of such a flow. The growth rates and configurations of large-scale galactic magnetic fields for this situation are close to those predicted by simple galactic dynamo models. At the same time, the model of a flow with recovery makes it possible to trace the role of the effective “forgetting” of correlations. The presence of this forgetting distinguishes interstellar turbulence from other types of random flows.     

Applying the HAZUS-MH software tool to assess seismic risk in downtown Ottawa,Canada

The aim of this paper is to present earthquake loss estimations for a portion of downtown Ottawa, Canada, using the HAZUS-MH (Hazards United States Multi-Hazard) software tool. The assessment is performed for a scenario earthquake of moment magnitude 6.5, at an epicentral distance of 15 km, occurring during business hours. A level 2 HAZUS-MH analysis was performed where the building inventory, microzonation studies, and site-specific ground motion hazard maps (2% exceedence probability in 50 years) were all improved based on local information. All collected data were assembled into a set of standard geodatabases that are compatible with the HAZUS-MH software using a GIS-specific procedure. The results indicate that the greatest losses are expected in unreinforced masonry buildings and commercial buildings. Sensitivity studies show that soil classes, the vulnerability of schools, and the spatial scale of loss estimations are also important factors to take into account.