基于HPLC特征图谱及主要成分含量测定等方法对不同产地甘草进行质量评价

目的：对不同产地的甘草进行全面质量研究,建立甘草药材的高效液相指纹图谱质量控制方法。方法：对30批来自新疆、内蒙古、甘肃及宁夏4个地区的甘草进行显微及薄层鉴别,并进行水分、总灰分、酸不溶性灰分及甘草苷、甘草酸含量测定,建立高效液相色谱指纹图谱的方法对其中21批质量合格的甘草进行质量评价。结果：30批不同产地的甘草药材鉴别及检查结果均合格,甘草酸含量均符合《中华人民共和国药典·一部》规定,有7批药材甘草苷含量不合格。指纹图谱共标定了14个共有峰,对其中3个共有峰进行了指认,21批甘草中仅4批相似度低于0.85。结论：不同产地甘草中甘草苷、甘草酸含量差异较大,宁夏及内蒙古产地甘草有效成分平均含量优于新疆与甘肃产甘草。本研究建立的甘草药材的高效液相指纹图谱质量控制方法能对不同产地甘草进行全面整体的质量评价。     

面向治理的地理学发展刍议

“四个面向”（面向世界科技前沿、面向经济主战场、面向国家重大需求、面向人民生命健康）已成为新时代中国科学发展的指针。治理是一个反映“四个面向”的国际前沿研究领域,也是地理学和其他学科研究的焦点。围绕地理学如何应对治理这一关键问题,基于人地耦合的理念,系统梳理国内外地理学进行治理研究的轨迹与特点,从价值、思想、方法、技术4个维度发掘面向治理的地理学发展路径,紧密联系地理学发展动态及治理现代化的实践,从基础研究、平台建设、人才培育3个方面提出发展策略。提升中国地理学在国际治理研究中的影响力,促进地理学与其他学科的交叉融合,将自然与人文有机结合的理念应用于社会治理,增进居民福祉,并服务国家战略和区域可持续发展。     

Microbial community changes in the digestive tract of the clam Meretrix petechialis in response to Vibrio parahaemolyticus challenge

Journal of Oceanology and Limnology - Disease in clams frequently occurred over the last decade and has become a serious threat to the clam aquaculture industry and natural stocks. Mass clam...     

Esophageal cancer spatial and correlation analyses：Water pollution,mortality rates,and safe buffer distances in China

Esophageal cancer exhibits one of the highest incidence and mortality rates in China. Malignant tumors caused by esophageal cancer, and the relationship to environmental factors has been the focus of many public health studies. This study applied spatial analysis to ascertain the relationship between water pollution and esophageal cancer mortality rates nationwide. We employed two datasets, including a national investigation of esophageal cancer rates and distribution, and national water quality grades in China's primary rivers and lakes. Esophageal cancer data were grouped based on different water quality grades, which included a scaled buffer distance from rivers and lakes. Non-parametric correlation analyses were performed to examine the presence or absence of the following correlations: (i) esophageal cancer mortality and buffer distance from rivers and lakes; and (ii) esophageal cancer mortality and water quality grade values. The present study revealed a significant positive correlation between widespread water pollution and esophageal cancer mortality nationwide; and a significant negative correlation between esophageal cancer mortality, and buffer distance from rivers and lakes.     

河南省承接产业转移的结构与空间考量

针对目前对中西部地区意义重大的产业转移承接问题,以河南省为例进行了探讨。指出产业转移承接过程对不同规模区域单元的影响不同,较小的单元受承接产业的影响较大,而较大的单元受到的影响较小且对承接产业的影响起着一定的制约作用。在讨论产业转移内涵特征以及河南省产业转移承接条件的基础上,对河南省产业转移承接的结构优化和空间布局进行分析,提出产业转移承接要受到河南省产业结构变化趋势约束,承接的产业应采取相对集中的空间格局,微观上集中在集聚区园区等各类产业发展平台,宏观上的重点则是主体功能上属于重点开发的中原城市群地区。     

2014 IGU Regional Conference held in Krakow,Poland

The 2014 Regional Conference of the International Geographical Union（IGU）was held on August 18-22 in Krakow,Poland.The total number of participants was 1374 from 64 countries and regions,including 357 from Poland.Germany,Japan,Czech,UK,China,Russia,USA,France and Hungary are the top countries of attendees in this conference.     

State of the art and practice of pavement anti-icing and de-icing techniques

Pavement snow and icing are worldwide problems, but effective countermeasures are just beginning to be developed in China. The two most common snow and ice removal methods are mechanical clearance and chemical melting, and the advantages and disadvantages of each approach are discussed here, including environmental and structural damage caused by corrosive snow melting agents. New developments in chemical melting agents and mechanical equipment are discussed, and an overview of alternative thermal melting systems is presented, including the use of geothermy and non-geothermal heating systems utilizing solar energy, electricity, conductive pavement materials, and infrared/microwave applications. Strategic recommendations are made for continued enhancement of public safety in snow and ice conditions.     

气象上寒潮天气两种不同统计方法的探讨

文章使用多伦县2001—2010年寒潮天气统计资料,分析了当地寒潮变化特征,通过对寒潮统计两种不同方法从降温特征、大气环流特征及地表覆盖几个方面进行分析,得出如下结论:按日最低气温降温幅度统计寒潮天气出现次数明显多于按日平均气温降温幅度统计寒潮天气出现的次数,尤其在初冬和冬末季节日最低气温变化比日平均气温变化幅度更加剧烈。     

CLM4.0模式对中国区域土壤湿度的数值模拟及评估研究

本文利用普林斯顿大学全球大气强迫场资料,驱动公用陆面过程模式（Community Land Model version 4.0,CLM4.0）模拟了中国区域1961～2010年土壤湿度的时空变化。将模拟结果与观测结果、美国国家环境预报中心再分析数据（National Centers for Environmental Prediction Reanalysis,NCEP）和高级微波扫描辐射计（Advanced Microwave Scanning Radiometer-EOS,AMSR-E）反演的土壤湿度进行了对比分析,结果表明CLM4.0模拟结果可以反映出中国区域观测土壤湿度的空间分布和时空变化特征,但东北、江淮和河套三个地区模拟值相对于观测值在各层次均系统性偏大。模拟与NCEP再分析土壤湿度的空间分布基本一致,与AMSR-E的反演值在35°N以北的分布也基本一致;从1961～2010年土壤湿度模拟结果分析得出,各层土壤湿度空间分布从西北向东南增加。低值区主要分布在新疆、青海、甘肃和内蒙古西部地区。东北平原、江淮地区和长江流域为高值区。土壤湿度数值总体上从浅层向深层增加。不同深度土壤湿度变化趋势基本相同。除新疆西部和东北部分地区外,土壤湿度在35°N以北以减少趋势为主,30°N以南的长江流域、华南及西南地区以增加为主。在全球气候变暖的背景下,CLM4.0模拟的夏季土壤湿度在不同程度上响应了降水的变化。中国典型干旱区和半干旱区土壤湿度减小,湿润区增加。其中湿润区土壤湿度对降水的响应最为显著,其次是半干旱区和干旱区。     

浅基础地基荷载-变形特性的分析研究

在土体主应力方向的旋转过程中,主应力方向与塑性主应变增量方向之间存在着非共轴现象,非共轴现象对应力-应变关系具有显著的影响。通过有限元二次开发,将角点结构非共轴理论应用到有限元程序ABAQUS中;对密砂单剪试验进行数值模拟,研究了非共轴现象及其对应力-应变关系的影响;采用离心模型试验方法,对圆形浅基础作用下饱和密砂地基荷载-变形特性进行试验研究;对离心模型试验进行数值模拟,将试验结果与数值计算结果进行对比,对非共轴模型的计算结果的合理性进行验证。研究结果表明:非共轴现象对浅基础地基荷载-变形特性具有显著的影响;当选取合理的非共轴塑性模量时,非共轴模型的计算结果与离心模型试验结果比较接近。