iTRAQ-based proteomic profiling of the marine medaka (Oryzias melastigma) gonad exposed to BDE-47

A recent study demonstrated that 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) may have an adverse effect on the reproduction in marine medaka (Oryzias melastigma), but the molecular mechanisms remain largely unknown. In this study, we investigated the protein expression profiles of male and female gonads of O. melastigma exposed to dietary BDE-47 at two dosages (0.65 and 1.30 μg/g/day, respectively) for 21 days. Extracted proteins were labeled with iTRAQ and analyzed on a MALDI TOF/TOF analyzer, as results, 133 and 144 unique proteins were identified in testis and ovary, respective, and they exerted dose- and sex-dependent expression patterns. In testis, among the 42 differentially expressed proteins; down-regulation of histone variants and parvalbumins implicated BDE-47 may disrupt the spermatogenesis and induce sterility in fishes. In ovary, 38 proteins were differentially expressed; the elevation of vitellogenins and apolipoprotein A–I expression indicated BDE-47 acts as an estrogen-mimicking compound and led to reproductive impairment in O. melastigma.     

基于GPD分布的黑河流域极端降水频率特征分析

采用广义帕雷托分布(GPD)对黑河流域极端降水的频率特征进行了分析。采用百分位数法、Hill图法、年交叉率法选取了极端降水阈值,借助L矩法对GPD分布的参数进行了估计;采用Mann-Kendall和Pettitt方法对超阈值日极端降水序列的平稳性进行了检验。结果表明：① 采用百分位数法和Hill图法得到的日极端降水阈值差别很大,在综合考虑以上两种方法的基础上,结合年交叉率法,最终确定了流域各站点日极端降水的阈值;② 根据Mann-Kendall和Pettitt方法,超阈值日极端降水序列基本满足平稳性假定;通过Kolmogorov-Smirnov检验以及理论频率曲线和经验频率曲线的拟合程度可以看出,GPD分布能够很好地拟合研究区极端降水的分布特征;③ 通过分析理论累积频率达到90%以上的极端降水可以发现,黑河流域20世纪60年代发生极端降水的次数最多,其次是90年代以后,70年代、80年代发生极端降水次数较少;在过去51年间,下游发生极端降水的次数最多,其次是中游和上游。     

Submicron-sized fluid inclusions and distribution of hydrous components in jadeite,quartz and symplectite-forming minerals from UHP jadeite–quartzite in the Dabie Mountains,China: TEM and FTIR investigation

Fluid inclusions and clusters of water molecules at nanometer-to submicron-scale in size have been investigated using transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FTIR) in jadeite, quartz and symplectite aegirine–augite, albite, taramite and magnetite corona minerals from ultrahigh-pressure (UHP) jadeite–quartzite at Shuanghe, the Dabie Mountains, China. Fluid inclusions from 0.003 μm to 0.78 μm in size occur in jadeite and quartz crystals, and a small number of fluid inclusions from 0.001 μm to 0.25 μm have also been detected in symplectite-forming minerals. Most of the fluid inclusions have round or negative crystal morphology and contain aqueous fluids, but some contain CO₂-rich fluids. They are usually connected to dislocations undetectable at an optical scale. The dislocations represent favorable paths for fluid leakage, accounting for non-decrepitation of most fluid inclusions when external pressure decreased at later stages, although there was partial decrepitation of some fluid inclusions unconnected to defect microstructures resulting from internal overpressure. Non-decrepitation and partial decrepitation of fluid inclusions resulted in changes of original composition and/or density. It is clear that identification of hidden re-equilibration features has significant implications for the petrological interpretation of post-peak metamorphic processes. Micro-FTIR results show that all jadeite and quartz samples contain structural water occurring as hydroxyl ions (OH⁻) and free water (H₂O) in the form of clusters of water molecules. The H₂O transformed from OH⁻ during exhumation and could have triggered and enhanced early retrograde metamorphism of the host rocks and facilitated plastic deformation of jadeite and quartz grains by dislocation movement, and thus the H₂O released during decompression might represent early-stage retrograde metamorphic fluid. The nominally anhydrous mineral (NAM) jadeite is able to transport aqueous fluids in concentrations of at least several hundred ppm water along a subduction zone to mantle depths in the form of clusters of water molecules and hydroxyl ions within crystals.     

基于手机邮箱监控天气雷达运行状态的方法

介绍了一种新的短信报警方法,通过巧妙应用中国移动的139邮箱业务,同样能完成对雷达状态的监控,并详细阐述了该方法的原理,最后对两种方法的优劣势进行了对比分析,为台站在设计监控软件时能有多种选择。     

锆石中磷的分带趋势、成因及地质意义

本文用电子探针对岩浆和变质重结晶锆石进行了成份分带的研究，结果表明，变质重结晶锆石具有从晶体中心至边缘Ｐ２Ｏ５含量增大的特点，可作为它们的成因标型特征，岩浆锆石则Ｐ２Ｏ５含量变化不稳定，本文论述了它们的成因。     

真实地震情况下人群疏散特征与模拟演练的差异:2008年汶川地震监控录像的分析

真实地震情况下人群疏散特征与模拟演练的差异是应急疏散的统计物理研究中的一个关键问题.本文通过互联网收集和分析了2008年5月12日汶川MS8.0地震中一些记录到地震时人群疏散的监控录像.这些监控录像不仅为真实地震情况下人员疏散行为的研究提供了目前仍十分稀缺的实例.而且可用于约束紧急情况下人群疏散的统计物理模型.对条件相似的真实地震情况下和模拟演练情况下的疏散人数一疏散时间进行研究,发现出口处的疏散人数和疏散时间呈显著的非线性关系,这与通过模拟演练所得出的线性关系具有明显的差异.     

MATHEMATICAL MODELS FOR LIQUID-SOLID TWO-PHASE FLOW

I INTRODUCTIONTurbulence models for single-phase fluid flows have been developed and widely applied in mechanical,aeronautical, environmental and hydraulic engineering, and other fields. The closure techniques for theReynolds-averaged Navier-Stokes equations for various levels of models including the simple turbulencemodel, one-equation turbulence model, k-s turbulence model and turbulence stress/flux model have beenverified to be physically reasonable and have acceptable accuracy in app…     

自我决定论下的高中地理探究活动设计——以"火星基地应该是什么样子"为例

与传统地理课堂相比,基于自我决定论(SDT)的课堂教学更加重视学生的心理健康以及内部学习动机的培养。本研究以2019年人教版高中地理必修一“火星基地应该是什么样子”为例,基于自我决定论的自主、能力、关系三个心理需要的视角,进行探究活动的设计,将理论具体落实到地理教学过程的各个环节,建立起基于自我决定论的地理教学路径与框架。