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51.
黑鲷(Acanthopagrus schlegeli)肿瘤坏死因子α cDNA的克隆及特征分析 总被引:1,自引:0,他引:1
采用同源克隆的方法,从黑鲷中获得肿瘤坏死因子(TNFα)全长cDNA序列。该序列含1288个核苷酸,可编码253个氨基酸的TNF前体蛋白。它是一种跨膜蛋白,无糖基化位点和信号肽结构。黑鲷TNFα与其它鱼类的TNFα的相似性很高,占据进化上独立的分支;与哺乳类TNFα和TNFG源于共同的祖先。基因结构分析显示,该基因含有TNF家族pmfile和TNF家族的标签序列;在参与TNFα基因二硫键形成的两个半胱氨酸和TNFα三聚体形成的位点高度保守;空间结构模拟显示,它与哺乳类TNFα的空间结构相似,都是由两个β折叠片组成,每个折叠片包含5个反向平行的β链。表达研究结果表明,黑鲷TNFα在检测的各个组织中均为组成型表达,表现为在刺激与非刺激鱼体中,都可以检测到黑鲷TNFα的表达,但是其表达水平在不同组织中有很大差异。黑鲷TNFα在头肾、脾脏和鳃的表达量较高,而在心脏、肝脏、血液、肾脏和大脑中表达量较低。 相似文献
52.
The Magellan seamounts began forming as large submarine shield volcanoes south of the equator during the Cretaceous. These
volcanoes formed as a cluster on the small Pacific plate in a period when tectonic stress was absent. Thermal subsidence of
the seafloor led to sinking of these volcanoes and the formation of guyots as the seamounts crossed the equatorial South Pacific
(10–0°S) sequentially and ocean surface temperatures became too high for calcareous organisms to survive. Guyot formation
was completed between about 59 and 45 Ma and the guyots became phosphatized at about 39–34 and 27–21 Ma. Ferromanganese crusts
began formation as proto-crusts on the seamounts and guyots of the Magellan Seamount cluster towards the end of the Cretaceous
up to 55 Ma after the formation of the seamounts themselves. The chemical composition of these crusts evolved over time in
a series of steps in response to changes in global climate and ocean circulation. The great thickness of these crusts (up
to 15–20 cm) reflects their very long period of growth. The high Co contents of the outer parts of the crusts are a consequence
of the increasing deep circulation of the ocean and the resulting deepening of the oxygen minimum zone with time. Growth of
the Co-rich Mn crusts in the Magellan Seamount cluster can be considered to be the culmination of a long journey through time. 相似文献
53.
在构造和气候的综合作用下,本区在早第三纪成为一个大型裂谷湖盆,并在沙四、沙三和沙一期因受古太平洋海泛影响而具有"近海"湖盆的特征,其演变经历了初始形成-强烈扩张-晚期扩张-收缩干涸四个阶段,构成一个完整的湖侵-湖退旋回和湖泊早期形成-中期扩张-晚期收缩三个亚旋回。 相似文献
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Studies on rain-runoff process in the peripheral mountainous area of the Sichuan Basin, which is regarded as a key ecological shelter, will contribute to flood control and environmental protection for the Upper Yangtze River Basin. In two typical catchments--the Fujiang River Catchment and the Wujiang River Catchment, rainfall simulations have been conducted to study the rain-runoff processes of yellow soil and limestone soil in three types of land use--forestland, farmland and grassland. Results showed that (1) within the same rainfall process, overland flow occurs first on farmland, then on grassland, and finally on forestland; (2) soil surface coverage has a great impact on the occurrence and amount of overland flow. The runoff amount can increase 2-4 times after the coverage is removed; (3) the infiltration before the occurrence of overland flow will decrease because of higher gravel contents of soil, but it takes no effect on infiltration once overland flow becomes stable; (4) the runoff coefficient of the limestone soil forestland is greater than that of the yellow soil forest land, but less than that of the farmland; (5) three empirical infiltration models, including Horton' model, Kostiakov' model, and modified Kostiakov' model, were compared by using the observed results under rainfall simulation. The results showed that the Kostiakov' model performed better than both the Horton' model and modified Kostiakov model. According to the results of this research, the Kostiakov's model can be used to simulate rainfall infiltration when water erosion is modeled in the peripheral mountainous area of the Sichuan Basin. 相似文献
60.
Xin Li Dongliang Wang Baoquan Liu Chunling Ren Jianying Guo Xuefeng Su Jian Wang 《中国地球化学学报》2008,27(4):412-419
The northern margin of the Qaidam Basin is one of the main oil-gas exploration areas in western China, where source rocks are composed mostly of Middle and Lower Jurassic dark mud shale, carbargillite and coal. A large number of subsurface and outcrop samples differing in lithology with different types of organic matter were selected for resource evaluation, research and calculation. And among them, 13 samples were used for simulation experiment on hydrocarbon generating potential of various source rocks. At first, two kinds of heating modes were compared through simulation experiment, including single temperature-step heating and continual heating. Perhaps, the process of hydrocarbon generation and expulsion occurred naturally between a close system and an open system. In addition, the first heating mode was convenient, and all its reaction products were involved in the whole thermal evolution, and the final simulation experimental results were basically in consistency with the natural evolution trend Therefore, the first heating mode was adopted and the hydrocarbon yield of every sample was worked out. According to the type and lithology of organic matter and the hydrocarbon yield of samples for simulation experiment, hydrocarbon generation and expulsion mode with three kinds of lithology and five types of source rock has been established to provide the basis for hydrocarbon generation evaluation, research and resource calculation. 相似文献