Is geographical proximity necessary in the innovation networks in the era of global economy?

In the analysis of geographical spillovers, a commonly accepted hypothesis is that the different actors of innovation need to be physically closed to one another because the transfer of tacit knowledge implies frequent face-to-face relations. This hypothesis is put under closer examination in this paper. The first section analyses the need for economic agents to be closely located to develop research and innovative activities, starting with the analysis of their need for co-ordination and using some case studies. Based on the example of three French regions, the second section examines the importance given by the local development policies to geographical proximity in order to support the rapid development of local networks favouring innovation. In both sections, nonlocal relations appear as a key factor to develop innovation. As a conclusion, nonlocal relations should be encouraged by local development policies in the same way as local relations.     

Distribution patterns of chlorophyll <Emphasis Type="Italic">a</Emphasis> in spring and autumn in association with hydrological features in the southern Yellow Sea and northern East China Sea

Two field studies were conducted to measure pigments in the Southern Yellow Sea (SYS) and the northern East China Sea (NECS) in April (spring) and September (autumn) to evaluate the distribution pattern of phytoplankton stock (Chl a concentration) and the impact of hydrological features such as water mass, mixing and tidal front on these patterns. The results indicated that the Chl a concentration was 2.43±2.64 (Mean ± SD) mg m^?3 in April (range, 0.35 to 17.02 mg m^?3) and 1.75±3.10 mg m^?3 in September (from 0.07 to 36.54 mg m^?3) in 2003. Additionally, four areas with higher Chl a concentrations were observed in the surface water in April, while two were observed in September, and these areas were located within or near the point at which different water masses converged (temperature front area). The distribution pattern of Chl a was generally consistent between onshore and offshore stations at different depths in April and September. Specifically, higher Chl a concentrations were observed along the coastal line in September, which consisted of a mixing area and a tidal front area, although the distributional pattern of Chl a concentrations varied along transects in April. The maximum Chl a concentration at each station was observed in the surface and subsurface layer (0–10 m) for onshore stations and the thermocline layer (10–30 m) for offshore stations in September, while the greatest concentrations were generally observed in surface and subsurface water (0–10 m) in April. The formation of the Chl a distributional pattern in the SYS and NECS and its relationship with possible influencing factors is also discussed. Although physical forces had a close relationship with Chl a distribution, more data are required to clearly and comprehensively elucidate the spatial pattern dynamics of Chl a in the SYS and NECS.     

Screening of extraction methods for glycoproteins from jellyfish (Rhopilema esculentum) oral-arms by high performance liquid chromatography

In order to select an optimum extraction method for the target glycoprotein (TGP) from jellyfish (Rhopilema esculentum) oral-arms, a high performance liquid chromatography (HPLC)-assay for the determination of the TGP was developed. Purified target glycoprotein was taken as a standard glycoprotein. The results showed that the calibration curves for peak area plotted against concentration for TGP were linear (r = 0.9984, y = 4.5895x+47.601) over concentrations ranging from 50 to 400 mgL-1. The mean extraction recovery was 97.84% (CV2.60%). The fractions containing TGP were isolated from jellyfish (R. esculentum) oral-arms by four extraction methods: 1) water extraction (WE), 2) phosphate buffer solution (PBS) extraction (PE), 3) ultrasound-assisted water extraction (UA-WE), 4) ultrasound-assisted PBS extraction (UA-PE). The lyophilized extract was dissolved in Milli-Q water and analyzed directly on a short TSK-GEL G4000PWXL (7.8 mm×300 mm) column. Our results indicated that the UA-PE method was the optimum extraction method selected by HPLC.     

The First Solar Seeing Profile Measurement with Two Apertures and Multiple Guide Regions

The sky brightness is a critical parameter for estimating the coronal observation conditions for a solar observatory. As part of a site-survey project in Western China, we measured the sky brightness continuously at the Lijiang Observatory in Yunnan province in 2011. A sky brightness monitor (SBM) was adopted to measure the sky brightness in a region extending from 4.5 to 7.0 apparent solar radii based on the experience of the Daniel K. Inouye Solar Telescope (DKIST) site survey. Every month, the data were collected manually for at least one week. We collected statistics of the sky brightness at four bandpasses located at 450, 530, 890, and 940 nm. The results indicate that aerosol scattering is of great importance for the diurnal variation of the sky brightness. For most of the year, the sky brightness remains under 20 millionths per airmass before local Noon. On average, the sky brightness is less than 20 millionths, which accounts for 40.41% of the total observing time on a clear day. The best observation time is from 9:00 to 13:00 (Beijing time). The Lijiang Observatory is therefore suitable for coronagraphs investigating the structures and dynamics of the corona.     

Monte-Carlo Simulations of Cosmic-ray and Internal Radiation Effects on ISOCAM on Board ISO

One of the main limitations to the sensitivity of the infrared camera ISOCAM on-board the Infrared Space Observatory (ISO) comes from responsivity variations and glitches caused by the impacts of charged particles in photo-detectors. Glitch rate measurements, glitch properties and removal methods have already been addressed during the first ISO detector workshop(Madrid, 1998) and published in a special issue of Experimental Astronomy. It appeared that glitch rate and most of glitch properties could be reproduced by Monte-Carlo simulations. This is very interesting in order to predict before launch the effect of charged particles in photo-detectors operated in space. This paper presents results of Monte-Carlo simulations of radiation effects on ISOCAM detectors. Glitch rates, spatial and energetic properties of glitches have been computed and are compared with measured values. This revised version was published online in July 2006 with corrections to the Cover Date.     

Groundwater-flow modeling in the Yucatan karstic aquifer, Mexico

The current conceptual model of the unconfined karstic aquifer in the Yucatan Peninsula, Mexico, is that a fresh-water lens floats above denser saline water that penetrates more than 40 km inland. The transmissivity of the aquifer is very high so the hydraulic gradient is very low, ranging from 7–10 mm/km through most of the northern part of the peninsula. The computer modeling program AQUIFER was used to investigate the regional groundwater flow in the aquifer. The karstified zone was modeled using the assumption that it acts hydraulically similar to a granular, porous medium. As part of the calibration, the following hypotheses were tested: (1) karstic features play an important role in the groundwater-flow system; (2) a ring or belt of sinkholes in the area is a manifestation of a zone of high transmissivity that facilitates the channeling of groundwater toward the Gulf of Mexico; and (3) the geologic features in the southern part of Yucatan influence the groundwater-flow system. The model shows that the Sierrita de Ticul fault, in the southwestern part of the study area, acts as a flow barrier and head values decline toward the northeast. The modeling also shows that the regional flow-system dynamics have not been altered despite the large number of pumping wells because the volume of water pumped is small compared with the volume of recharge, and the well-developed karst system of the region has a very high hydraulic conductivity. Electronic Publication     

厚壳贻贝（Mytilus coruscus）McNF-κB基因的克隆及其在发育中的作用

核因子κB（Nuclear Factor kappa-B,NF-κB）具有免疫、炎症、凋亡、细胞增殖和发育的调节作用,目前NF-κB在脊椎动物和果蝇中的研究较为丰富,在贝类中的报道较少。为进一步探究NF-κB在厚壳贻贝（Mytilus coruscus）免疫和发育中的作用,本研究克隆了厚壳贻贝McNF-κB基因的序列全长,其全长为4 087 bp,开放阅读框为2 613 bp,编码871个氨基酸,具有典型的锚蛋白重复序列（ankyrinrepeat, ANK）结构域和死亡结构域。氨基酸序列分析结果发现,该基因与欧洲贻贝（Mytilus edulis）和地中海贻贝（Mytilus galloprovincialis）分别具有72.76%和66.58%同源性,且在系统进化树中与欧洲贻贝和地中海贻贝聚为一支。经实时荧光定量PCR（qRT-PCR）技术检验表明,McNF-κB基因于厚壳贻贝各组织均有分布,在鳃中表达最高;McNF-κB基因在厚壳贻贝眼点幼虫阶段和稚贝阶段均有表达,且在稚贝阶段表达量显著高于眼点幼虫阶段。利用RNA干扰技术沉默眼点幼虫McNF-κB基因后幼虫变态率显著下降,推测McNF-κB基因调控厚壳贻贝幼虫变态过程。本研究为探究McNF-κB基因如何调控厚壳贻贝发育奠定了基础。     

海南岛直尾颚足钩虾(甲壳动物:端足目,颚足钩虾科)的补充描述

颚足钩虾属 Maxillipius (端足目,颚足钩虾科 Family Maxillipiidae)中,迄今仅有2种,即直尾颚足钩虾 Maxillipius rectitelson Ledoyer和共栖颚足钩虾 Maxillipius commensalis Ledoyer。直尾颚足钩虾的模式标本采自马达加斯加,仅有雌体。虽然后来Ledoyer(1986)又进行了补充描记,但因缺乏雄体标本,使该种的描述不完善。作者在海南岛潮间带采集中,获得较多该种标本,仅雄体就有27个,并发现雄、雌第1触角形态表现为雌、雄异形(sexual dimorphism)。这与Thomas (1996)所描述的Maxillipius commensalis Ledoyer雌、雄体形态差异相似,即在雄体第1触角第3柄节上具柄突(callynophore),该柄突在 Maxillipiidae 科中为 Maxillipius 属区别于 Maxillipides 属的主要特征。 本文为直尾颚足钩虾 Maxillipius rectitelson Ledoyer 的补充描述。     

黄河口及其邻近水域强壮箭虫密度的时空分布及其与环境因子的关系

为探究强壮箭虫（Sagitta crassa）在黄河口及其邻近水域的时空分布特征及其与生物和非生物环境等因子的关系,本文依据2013—2014年在黄河口及其邻近水域6个航次的调查数据,采用丛生指标（I）、聚块性指标（A）和负二项分布参数的倒数（C_A）等聚集指标,分析了强壮箭虫的空间分布特征;应用广义可加模型（GAM）研究了强壮箭虫密度的时空分布和环境因子的关系。结果表明,黄河口及其邻近水域强壮箭虫平均密度为21.85 ind/m3,春、秋季高,冬、夏季低;其密度的空间分布以黄河入海口附近水域为密集中心,向远岸水域逐渐降低;强壮箭虫在黄河口及其邻近水域的聚集特征随密度的变化存在两次聚集和两次扩散;水深、表层水温和浮游桡足类密度是影响其密度时空分布的主要因子,总偏差解释率为55.11%,强壮箭虫密度随水深的增加而减小,随表层水温的升高先增加后减小,随桡足类密度的增加而增加。强壮箭虫密度受黄河口及其邻近水域环境因子变动的影响,具有明显的季节变化和空间分布规律。     

洛阳市暴雨时空分布特征

对洛阳市1961-2005年10个站逐日雨量资料统计分析结果表明:洛阳暴雨集中在7-9月,且7-8月单站暴雨较多。有2个暴雨多发区域中心,一个在北部的丘陵区,另一个在南部山区。年区域暴雨出现≥4次时,有准3 a的周期变化规律;≤3次时,有准5 a的周期变化规律。