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51.
In this paper we develop analytical solutions for scratch hardness–strength relations for cohesive‐frictional materials of the Mohr–Coulomb and Drucker–Prager type. Based on the lower bound yield design approach, closed‐form solutions are derived for frictionless scratch devices, and validated against computational upper bound and elastoplastic finite element solutions. The influence of friction at the blade–material interface is also investigated, for which a simple computational optimization is proposed. Illustrated for scratch tests on cement paste, we show that the proposed solutions provide a convenient way to determine estimates of cohesion and friction parameters from scratch data, and may serve as a benchmark to identify the relevance of strength models for scratch test analysis. Copyright © 2011 John Wiley & Sons, Ltd.  相似文献   
52.
The neuroprotective role of P-glycoprotein, a multixenobiotic resistance transporter (ABCB1/MDR1), in the blood-brain barrier in fish was examined using behavioural toxicological assays. P-glycoprotein acts as cellular efflux pump to prevent substrates from accumulating in the brain, including environmental contaminants such as ivermectin, a common aquaculture pesticide and mammalian anti-parasitic drug. The behavioural toxicological assays were developed to determine the neuropathological effect of ivermectin in killifish (Fundulus heteroclitus). P-glycoprotein function and thus blood-brain barrier integrity can be compromised by chemosensitizers that inhibit transport activity. Fish treated with ivermectin and the P-glycoprotein inhibitor cyclosporin A were significantly more sensitive and succumbed more rapidly to tilting, lethargy, slowing of pectoral-fin movement and loss of haptic-reactivity compared to fish treated with ivermectin-only. P-glycoprotein inhibition is associated with significantly earlier onset and increased mortality in ivermectin-exposed fish. Our results suggest that P-glycoprotein confers resistance against ivermectin-induced behavioural neuropathology and mortality in fish. This assay provides us with a non-invasive tool to study P-glycoprotein function in the blood-brain barrier and evaluate the behavioural effects of potential environmental neurotoxins.  相似文献   
53.
Soil physical characteristics can influence terrestrial hydrology and the energy balance and may thus affect land–atmosphere exchanges. However, only few studies have investigated the importance of soil textures for climate. In this study, we examine the impact of soil texture specification in a regional climate model. We perform climate simulations over Europe using soil maps derived from two different sources: the soil map of the world from the Food and Agricultural Organization and the European Soil Database from the European Commission Joint Research Center. These simulations highlight the importance of the specified soil texture in summer, with differences of up to 2 °C in mean 2-m temperature and 20 % in precipitation resulting from changes in the partitioning of energy at the land surface into sensible and latent heat flux. Furthermore, we perform additional simulations where individual soil parameters are perturbed in order to understand their role for summer climate. These simulations highlight the importance of the vertical profile of soil moisture for evapotranspiration. Parameters affecting the latter are hydraulic diffusivity parameters, field capacity and plant wilting point. Our study highlights the importance of soil properties for climate simulations. Given the uncertainty associated with the geographical distribution of soil texture and the resulting differences between maps from different sources, efforts to improve existing databases are needed. In addition, climate models would benefit from tackling unresolved issues in land-surface modeling related to the high spatial variability in soil parameters, both horizontally and vertically, and to limitations of the concept of soil textural class.  相似文献   
54.
55.
The city of Oran is exposed to a significant seismic hazard, as almost all the northern Algeria territory, where numerous casualties and severe damage occurred in the last decades due to several moderate to large earthquakes. A mitigation policy should include the establishment of priorities to reduce the vulnerability of existing buildings based on the knowledge of the actual urban fabrics. The complexity of vulnerability assessment requires a gradual approach from the urban scale to the building scale. The study reported in this paper corresponds to the first step of such an approach, i.e., a preliminary study of the seismic vulnerability and expected damage within an urban district of the city of Oran, based on a non-dedicated data base from a building survey previously performed for other purposes. The main goals of this study are twofold: (1) an assessment of the degree of uncertainty and robustness of such results through a comparison of the results derived from different urban vulnerability methods (GNDT 2; RISK-UE LM1; and VULNERALP 2.0) and (2) an assessment of the actual level of seismic risk in the city of Oran. Cross-method comparisons and correlations highlight a satisfactory agreement between mean damage estimates at the urban scale, despite significant scattering at the single building scale, and uncertainty levels which vary significantly from one method to the other. For a given scenario, the three methods provide damage estimates lying within half an EMS damage degree of one another, with some systematic positive bias for VULNERALP and negative bias for RISK-UE LM1, especially for masonry buildings. The expected mean damage is very important for intensities 9 and 10, with an average damage grade around 3–4 for intensity 9 and 4–5 for intensity 10. The spatial distribution of damage systematically exhibits larger values in the northern, older, commercial area, than in the southern, more recent and more residential area, in relation to the building typology and the existence of several aggravating factors. Some areas of higher vulnerability / damage can be distinguished, which should receive particular attention for retrofitting priorities or urban planning decisions, also taking into account their cultural heritage value.  相似文献   
56.
57.
When data is available, the estimation of site effects is usually performed using the “standard spectral ratio” (SSR) technique with respect to an outcropping, reference rock site. This study uses the Japanese KiK-net network, which has more than 600 pairs of surface-downhole stations allowing the computation of empirical borehole transfer functions, consisting of mean spectral ratios of surface over downhole recordings. The borehole transfer function deviates from the SSR in two respects: the reference is located at depth, and the downhole velocity varies from one site to another. These differences bias the estimation of the transfer function with reference to a standard outcrop rock site. The goal of this paper is to develop a simple and robust methodology to correct for such bias. The proposed correction procedure consists of two steps: a depth correction designed to account, in a simplified and physically acceptable way, for the existence at depth of destructive interferences and the absence of free-surface effects in the high-frequency range; and an impedance correction designed to normalize the shear wave velocity at depth. The depth correction involves a simple, frequency-dependent curve to be adapted for each site as a function of the first destructive interference frequency at depth. The impedance normalization combines the use of “generic” rock velocity profiles and a quarter-wavelength approach, resulting in a smooth frequency-dependent amplitude correction. The proposed methodology is applied on a large subset of KiK-net data in view of analysing the correlation between site amplification factors and site parameters in a companion paper.  相似文献   
58.
The strike slip Yammouneh fault is the longest fault in Lebanon, crossing the territory from South to North. It was responsible for major historical earthquakes like the 1202 A.D. earthquake, estimated to Ms7.6. This paper presents a site-specific estimation of the ground motion caused by a potential Mw7.5 earthquake on the Yammouneh fault, similar to the 1202 event, for various sites within the Beirut area. The empirical Green’s function technique EGF is used to estimate the median and the standard deviations of the seismic ground motion at the reference station BHL, taking into account epistemic and aleatory uncertainties related to source parameters. These uncertainties were quantified through a sensitivity analysis of the position of the rupture nucleation Xnuc, the slip roughness parameter K, the corner frequency fc and the magnitude Mc of the EGF. The rock ground motion is then transferred to various other sites within the Beirut area, using instrumental Fourier transfer functions. Site amplification factors are next deduced by computing the ratio between response spectra at sediment sites and at a reference rock station. Considering the limits of the EGF method in the near field of extended sources, the EGF approach is considered only up to a magnitude Mw of 6.5. Selected Ground Motion Predictive Equations are then used to simulate a Mw7.5 event at a reference station. By applying the amplification factors, the response spectra at the different sites of Beirut are also calculated and compared with the actual response spectra used in the Lebanese regulations.  相似文献   
59.
Results from multiple model simulations are used to understand the tropical sea surface temperature (SST) response to the reduced greenhouse gas concentrations and large continental ice sheets of the last glacial maximum (LGM). We present LGM simulations from the Paleoclimate Modelling Intercomparison Project, Phase 2 (PMIP2) and compare these simulations to proxy data collated and harmonized within the Multiproxy Approach for the Reconstruction of the Glacial Ocean Surface Project (MARGO). Five atmosphere–ocean coupled climate models (AOGCMs) and one coupled model of intermediate complexity have PMIP2 ocean results available for LGM. The models give a range of tropical (defined for this paper as 15°S–15°N) SST cooling of 1.0–2.4°C, comparable to the MARGO estimate of annual cooling of 1.7 ± 1°C. The models simulate greater SST cooling in the tropical Atlantic than tropical Pacific, but interbasin and intrabasin variations of cooling are much smaller than those found in the MARGO reconstruction. The simulated tropical coolings are relatively insensitive to season, a feature also present in the MARGO transferred-based estimates calculated from planktonic foraminiferal assemblages for the Indian and Pacific Oceans. These assemblages indicate seasonality in cooling in the Atlantic basin, with greater cooling in northern summer than northern winter, not captured by the model simulations. Biases in the simulations of the tropical upwelling and thermocline found in the preindustrial control simulations remain for the LGM simulations and are partly responsible for the more homogeneous spatial and temporal LGM tropical cooling simulated by the models. The PMIP2 LGM simulations give estimates for the climate sensitivity parameter of 0.67°–0.83°C per Wm−2, which translates to equilibrium climate sensitivity for doubling of atmospheric CO2 of 2.6–3.1°C.  相似文献   
60.
A 2.5 × 2.5° gridded summer (April–September) drought reconstruction over the larger Mediterranean land area (32.5°/47.5°N, 10°W/50°E; 152 grid points) is described, based on a network of 165 tree-ring series. The drought index used is the self-calibrated Palmer Drought Severity Index, and the period considered is 1500–2000. The reconstruction technique combines an analogue technique for the estimation of missing tree-ring data with an artificial neural network for optimal non-linear calibration, including a bootstrap error assessment. Tests were carried out on the various sources of error in the reconstructions. Errors related to the temporal variations of the number of proxies were tested by comparing four reconstructions calibrated with four different sized regressor datasets, representing the decrease in the number of available proxies over time. Errors related to the heterogeneous spatial density of predictors were tested using pseudo-proxies, provided by the global climate model ECHO-G. Finally the errors related to the imperfect climate signal recorded by tree-ring series were tested by adding white noise to the pseudo-proxies. Reconstructions pass standard cross-validation tests. Nevertheless tests using pseudo-proxies show that the reconstructions are less good in areas where proxies are rare, but that the average reconstruction curve is robust. Finally, the noise added to proxies, which is by definition a high frequency component, has a major effect on the low frequency signal, but not on the medium frequencies. The comparison of the low frequency trends of our mean reconstruction and the GCM simulation indicates that the detrending method used is able to preserve the long-term variations of reconstructed PDSI. The results also highlight similar multi-decadal PDSI variations in the central and western parts of the Mediterranean basin and less clear low frequency changes in the east. The sixteenth and the first part of the seventeenth centuries are characterized by marked dry episodes in the west similar to those observed in the end of the twentieth century. In contrast, the eighteenth and nineteenth centuries (Little Ice Age) are characterized by dominant wet periods. In the eastern part of the Mediterranean basin the observed strong drought period of the end of the twentieth century seems to be the strongest of the last 500 years.  相似文献   
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