| 320排螺旋CT单次心动周期手动触发双低剂量CTCA的可行性研究 |
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| 引用本文： | 赵常红, 刘挨师, 郝粉娥. 320排螺旋CT单次心动周期手动触发双低剂量CTCA的可行性研究[J]. CT理论与应用研究, 2018, 27(5): 583-591. DOI: 10.15953/j.1004-4140.2018.27.05.04 |
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| 作者姓名： | 赵常红 刘挨师 郝粉娥 |
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| 作者单位： | 1. 内蒙古医科大学附属医院影像诊断科, 呼和浩特 010050; |
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| 基金项目： | 内蒙古自治区自然科学基金（2016MS08144）。 |
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| 摘 要： | 目的：通过改良320排CT单次心动周期冠状动脉造影扫描技术与对比剂注射技术，以降低辐射剂量与对比剂剂量，并评价技术可行性。方法：前瞻性选取2017年10月至2018年1月之间拟行CTCA扫描的低心率、标准体型患者51例。所选患者随机分为A和B两组。A和B两组管电压分别设置为80 kV和100 kV，均依据体质量指数设置管电流300~500 mA。两组依体质量注射速率分别采用5.0~7.0 mL/s和3.5~5.5 mL/s；对比剂剂量分别采用20~30 mL和35~55 mL。A组采用实时手动触发，B组采用追踪自动触发。评价并比较两组对比剂剂量、辐射剂量与图像质量。结果：A、B两组对比剂剂量差异具有统计学意义，A组对比剂剂量仅28.20±6.44 mL，较B组45.58±6.05 mL降低约30%（t=-9.935，P=0.000）。A组较B组降低约45%的辐射剂量（0.96 mSv±0.27 mSv vs 1.76 mSv±0.28 mSv，t=-10.412，P=0.000）。A组平均评分3.59±0.58，B组平均评分3.66±0.53，Z=-1.618，P=0.106，差异无统计学意义。A组CNR较B组降低13%（20.26±7.34 vs 23.29±7.06，t=-3.350，P=0.001）。结论：低剂量方案可以大幅度减低对比剂剂量与辐射剂量，而图像质量可评估性无明显影响。
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| 关 键 词： | 体层摄影术 X线计算机 冠状动脉 图像质量 辐射剂量 对比剂剂量 |
| 收稿时间： | 2018-03-29 |
320-detector Row CT Double Low-dose CTCA with Manual Bolus Tracking: A Feasible Study |
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| ZHAO Chang-hong, LIU Ai-shi, HAO Fen-e. 320-detector Row CT Double Low-dose CTCA with Manual Bolus Tracking: A Feasible Study[J]. CT Theory and Applications, 2018, 27(5): 583-591. DOI: 10.15953/j.1004-4140.2018.27.05.04 |
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| Authors: | ZHAO Chang-hong LIU Ai-shi HAO Fen-e |
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| Affiliation: | 1. Department of Radiology, the Affiliated Hospital of Inner Mongolia Medical University, hohhot 010050, China;2. Department of Radiology, Chifeng Municipal Hospital, Chifeng 024000, China |
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| Abstract: | Objective: To evaluate the value of double low-dose CT coronary angiography (CTCA) by single cardiac cycle acquisition with 320-detector row CT. Methods: 51 patients with low heart rate and normal body type enrolled this study from October 2017 to January 2018. All patients were divided into two groups (Group A and Group B). Group A included 25 patients with tube voltage 80 kV and tube current tailored to body mass index (BMI) (300-500 mA), the injection rate and volume of contrast agent (20-30 mL) tailored to body mass (BM). Group B included 26 patients with tube voltage 100 kV and tube current tailored to BMI (300-500 mA), the injection rate and volume of contrast agent (35-45 mL) tailored to BM. Two groups were evaluated by contrast agent, radiation dose and image quality. P values below 0.05 were considered to be statistically significant. Results: All patients successfully underwent single cardiac cycle CTCA. The mean contrast agent for group A was 28.20 mL; this represents a 30% reduction as compared with that group B (mean, 45.58 mL; t=-9.935, P<0.001). The mean effective dose for group A was 0.96 mSv; this represents a 45% reduction as compared with that group B (mean, 1.76 mSv; t=-10.412, P<0.001). The mean image quality score was 3.59±0.58 obtained with Group A versus 3.66±0.53 obtained with Group B (Z=-1.618, P=0.106). The mean CNR was 20.26±7.34 obtained with Group A versus 23.29±7.06 obtained with Group B (t=-3.350, P=0.001). Conclusion: Double low dose CTCA may decrease the contrast agent and radiation dose keeping image quality assessable in specify patients. |
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| Keywords: | tomography X-ray computed coronary artery image quality radiation dose contrast agent |
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