| 海藻硫酸多糖911抗乙脑病毒作用的观察 |
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| 引用本文： | 王文涛,李钟铎,邢善田,周金黄,管华诗.海藻硫酸多糖911抗乙脑病毒作用的观察[J].中国海洋大学学报(自然科学版),1992(Z1). |
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| 作者姓名： | 王文涛 李钟铎 邢善田 周金黄 管华诗 |
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| 作者单位： | 青岛海洋大学
(王文涛)，青岛海洋大学军事医学科学院
(李钟铎，邢善田，周金黄)，青岛海洋大学(管华诗) |
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| 摘 要： | 采用体外微量细胞病变抑制实验及体内半数致死量LD_(50)测定法,分别观察海藻硫酸多糖911对乙型脑炎病毒的作用。结果表明,海藻硫酸多糖911在体外适宜的浓度条件下,对乙型脑炎病毒有一定的抑制作用,但对病毒无中和作用。体内给药,911对乙型脑炎病毒无明显抑制作用。
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| 关 键 词： | 海藻硫酸多糖 乙型脑炎病毒(JEV) 细胞病变CPE 半数细胞病变量(TCID_(SO) 半数致死量(LD_(SO)) |
THE EFFECTS OF MARINE POLYSACCHRIDE SULFATE 911 ON ENCEPHATITIS B VIRUS |
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| Wang Wentao Li Zhongduo Xing Shantian Zhou Jinhuang Guan Huashi.THE EFFECTS OF MARINE POLYSACCHRIDE SULFATE 911 ON ENCEPHATITIS B VIRUS[J].Periodical of Ocean University of China,1992(Z1). |
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| Authors: | Wang Wentao Li Zhongduo Xing Shantian Zhou Jinhuang Guan Huashi |
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| Institution: | Wang Wentao Li Zhongduo Xing Shantian Zhou Jinhuang Guan Huashi(Ocean University of Qingdao)(Military Academy of Medical Sciences) |
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| Abstract: | The effects of marine polysaccharide sulfate-911 on encephalitis B virus was investigated through in vitro study of the inhibition on trace cellular damage and the determination of LD50.The results show that marine polysaccharide sulfate can dramatially inhibit encephalitis B virus in vitro under optimal concentrations with no neutralizing effects on vivo study. |
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| Keywords: | marine polysaccharide sulfate Japanese encephalitis virus cellular pathological changes |
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