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Enzymatic synthesis of methyl-galactoaldehyde
Authors:Wang Qun  Yu Guangli
Institution:1. Division of Medicinal and Natural Products Chemistry, College of Pharmacy, The University of Iowa, IA, 52242, USA
2. Institute of Marine Food and Drug, Ocean University of Qingdao, Qingdao 266003, P.R. China
Abstract:Methyl-galactosides were oxidized at room temperature by galactose oxidase in a one-step reaction and afforded methyl-galactoaldehyde in excellent yield and high purity. The resulting galactoaldehyde as a useful intermediate can be directly used in glycopeptide synthesis.
Keywords:methyl galactoside  galactose oxidase  enzymatic synthesis  galactoaldehyde
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