增强CT结肠造影在结直肠癌术前评估中的临床应用研究

目的：通过描述增强CTC评价结直肠癌临床分期T、N分期的准确性,并与病理分期对照,明确其临床应用价值。方法：本研究共入选诊断为非转移性结直肠癌的病人40例,肠道准备后进行增强CTC扫描,管电压120kV,管电流300mA。评价临床分期并与病理分期对照,分别计算T、N分期符合率并进行一致性检验,以P〈0.05认为差异具有统计学意义。结果：临床分期T分期符合率77.5%,一致性较好（k=0.665,P=0.000）,N分期符合率82.5%,一致性好（k=0.734,P=0.000）,总符合率67.5%。结论：增强CTC可以有效地应用于结直肠癌术前评估,尤其是准确的临床分期,具有指导制定治疗方案、评估预后的重要临床价值。

Clinical Application and Study of CT Colonography in the Evaluation of Colorectal Cancer

Objective： To evaluate the accuracy of the staging of the colorectal cancer, T, N by describing the evaluation of contrast-enhanced CTC, comparing the clinical pathological staging and clarify its clinical application value. Methods： In the study, 40 patients are selected, contracting non metastatic colorectal cancer, who were performed the scan of contrast-enhanced CTC, the tube voltage is 120 kV and the tube current is 300 mA. Evaluate the clinical staging, make comparison with the pathological staging, calculate the coincidence of T and N staging and conduct consistency test, only to draw a conclusion that there is statistical significance（P〈0.05）. Results： The coincidence rate of T staging is 77.5%, which is favorable（k = 0.665, P = 0.000）, and the coincidence rate of N staging is 82.5%, which is more favorable,（k = 0.734, P = 0.000）, and the total coincidence rate is 67.5%. Conclusion： The contrast-enhanced CTC can be applied in the evolution of colorectal cancer before surgery, especially can help the clinical staging accurately, and have some important clinical values in determining therapeutic methods and evaluating the prognosis of the patients.