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Studies on the Effect of DDT on the Regeneration of Cutaneous Wounds in Mystus (mystus) vittatus Bl. (Bagridae)
Authors:Meena Saxena  S. K. Kulshrestha
Abstract:The effects of DDT on the regeneration of cutaneous wounds has been studied in Mystus (mystus) vittatus. The fishes were locally collected, they were inflicted incised wounds surgically and kept in 0.01 and 0.15 ppm concentrations of DDT. The regenerating skin at different stages of development ranging from 15 min to 25 d after the injury was studied through microtomy sections. The following toxic effects were studied:
  • A small amount of DDT accumulated in the subcutis at the 25 days stage,
  • the regeneration of wounds under DDT stress has been slower, delayed or irregular,
  • the secretion of fibrinous exudate has been copious,
  • epithelization and fibroblastic activities have been slower,
  • the higher concentration of 0.15 ppm of DDT produced more toxic effects than the lower concentration of 0.01 ppm,
  • the earlier stages of wound healing up to 3 d have been more adversely affected than later stages.
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