|
|||||
|
|
Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed |
|
| Authors: | Liu Changshui Zang Kun Li Shihao Li Fuhua Ma Qingjun |
| Institution: | 1.Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, 266071, China ;2.Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266000, China ;3.University of Chinese Academy of Sciences, Beijing, 100049, China ;4.Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, 266071, China ; |
| Abstract: | Journal of Oceanology and Limnology - Thymidylate synthase (TS) is a key enzyme in the de novo biosynthesis of thymidine monophosphate, serving as a well-known drug target in chemotherapy against... |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |