Abstract: | The phenol-degrading system which can be induced in Rhodococcus spec. P 1 brings about the metabolization of phenol via the β-ketoadipate path (ortho-cleavage of catechol). For the more precise characterization of the degradation performance investigations were made into the influences of different carbon sources: glucose, galactose, ribose, arabinose, xylose, acetate, citricacid, mandelic acid, protocatechoic acid, glycerol, tryptophane, phenylalanine and the complex substrate of nutrient broth as well as succinate, catechol and benzoate. Only the three last-named substances show an influence: succinate inhibits only the synthesis of phenol hydroxylase, catechol and benzoate inhibit the synthesis and activity of phenol hydroxylase. As a comparison of the results with literature shows, even at the same path of degradation there are different regulating mechanismus in the different microorganisms. |