| GROWTH PROMOTION OF RED SEA BREAM, PAGROSOMUS MAJOR, BY ORAL ADMINISTRATION OF RECOMBINANT EEL AND SALMON GROWTH HORMONE |
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| 作者姓名： | 徐迎利 苗宏志 刘振辉 邓勇 兰山 王尧 张培军 徐斌 麦康森 |
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| 作者单位： | [1]FisheriesCollege,OceanUniversityofQingdao,Qingdao266003,China [2]ExperimentalMarineBiologicalLaboratory,InstituteofOceanology,ChineseAcademyofSciences,Qingdao266071,China [3]MarineLifeScienceCollege,OceanUniversityofQingdao,Qingdao266003,China |
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| 摘 要： | Recombinant eel GH and yeast containing chinook salmon growth hormone (reGHand rcsGH) were incorporated into gelatin and sodium alginate (reGH-GS and rcsGH-GS) or polymer ma-trix (reGH-HP55) to protect the hormone from proteolytic cleavage in the stomach. The diets containin greGH-GS, rcsGH-GS, reGH-HP55 and free-reGH or uncoated-rcsGH were administered to red sea bream. Feeding of reGH-GS, reGH-HP55 and rcsGH-GS diets resulted in significant increases in body weight and fork length over those of controls. These results strongly suggest that gelatin and sodium algi-nate as well as polymer matrix protected the hormone from proteolytic enzymes in the gastrointestinal tract to allow the bioactive hormone to enter the circulation and eventually stimulato fish growth.
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| 关 键 词： | 促进生长 荷尔蒙 生长激素 红海 鲤科鱼 |
| 收稿时间： | 19 April 2000 |
| 修稿时间： | 26 December 2000 |
Growth promotion of red sea bream,Pagrosomus major, by oral administration of recombinant eel and salmon growth hormone |
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| Bin Xu,Kang-sen Mai,Ying-li Xu,Hong-zhi Miao,Zhen-hui Liu,Yong Dong,Shan Lan,Rao Wang,Pei-jun Zhang.GROWTH PROMOTION OF RED SEA BREAM, PAGROSOMUS MAJOR, BY ORAL ADMINISTRATION OF RECOMBINANT EEL AND SALMON GROWTH HORMONE[J].Chinese Journal of Oceanology and Limnology,2001,19(2):141-146. |
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| Authors: | Bin Xu Kang-sen Mai Ying-li Xu Hong-zhi Miao Zhen-hui Liu Yong Dong Shan Lan Rao Wang Pei-jun Zhang |
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| Institution: | (1) Fisheries College, Ocean University of Qingdao, 266003 Qingdao, China;(2) Present address: Experimental Marine Biological Laboratory, Institute of Oceanology, Chinese Academy of Sciences, 7 Nanhai Road, 266071 Qingdao, China;(3) Marine Life Science College, Ocean University of Qingdao, 266003 Qingdao, China |
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| Abstract: | Recombinant eel GH and yeast containing chinook salmon growth hormone (reGH and rcsGH) were incorporated into gelatin and
sodium alginate (reGH-GS and rcsGH-GS) or polymer matrix (reGH-HP55) to protect the hormone from proteolytic cleavage in the
stomach. The diets containing reGH-GS, rcsGH-GS, reGH-HP55 and free-reGH or uncoated-rcsGH were administered to red sea bream.
Feeding of reGH-GS, reGH-HP55 and rcsGH-GS diets resulted in significant increases in body weight and fork length over those
of controls. These results strongly suggest that gelatin and sodium alginate as well as polymer matrix protected the hormone
from proteolytic enzymes in the gastrointestinal tract to allow the bioactive hormone to enter the circulation and eventually
stimulate fish growth.
This study was supported by a grant (No. 96D06059) from the Natural Science Foundation of Shandong Province, China. |
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| Keywords: | growth promotion hormone red sea bream |
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