| 一种短指软珊瑚Sinularia sp.克生活性筛选及其低极性成分GC/MS分析 |
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| 引用本文： | 王长云,刘海燕,孙雪萍,李秀保,郑彩娟,韩磊,邵长伦,管华诗.一种短指软珊瑚Sinularia sp.克生活性筛选及其低极性成分GC/MS分析[J].中国海洋大学学报(自然科学版),2009,39(5). |
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| 作者姓名： | 王长云 刘海燕 孙雪萍 李秀保 郑彩娟 韩磊 邵长伦 管华诗 |
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| 作者单位： | 1. 中国海洋大学医药学院,海洋药物教育部重点实验室,山东,青岛,266003
2. 中国科学院南海海洋研究所,广东,广州,510000 |
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| 基金项目： | 国家自然科学基金项目(40776073);;国家高技术研究发展计划专项(908-01-ST12908-02-05-04);;国家科技基础性工作专项(2007FY210500);;国家教育部科技创新工程重大项目培育资金(706038);;国家教育部新世纪优秀人才支持计划(NCET-05-0600)资助 |
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| 摘 要： | 采用卤虫致死和细胞毒活性筛选模型,对1种中国南海短指软珊瑚Sinularia sp.的乙醇提取物及各有机相进行了克生活性测定。结果表明,克生活性物质主要集中在石油醚相中。采用GC/MS技术,对石油醚相进行了分析,鉴定了15个化合物,主要为脂类和甾体类化合物;从石油醚相的甾醇部分鉴定了6个化合物,主要为麦角甾醇衍生物,占总甾醇含量的75.7%。推测甾醇类化合物是短指软珊瑚Sinularia sp.的主要克生活性物质。
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| 关 键 词： | 软珊瑚 短指软珊瑚 克生活性 甾醇类 GC/MS |
The Allelopathic Activity Evaluation and the GC/MS Analysis of the Low Polar Components from a Soft Coral Sinularia sp. |
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| WANG Chang-Yun,LIU Hai-Yan,SUN Xue-Ping,LI Xiu-Bao,ZHENG Cai-Juan,HAN Lei,SHAO Chang-Lun,GUAN Hua-Shi.The Allelopathic Activity Evaluation and the GC/MS Analysis of the Low Polar Components from a Soft Coral Sinularia sp.[J].Periodical of Ocean University of China,2009,39(5). |
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| Authors: | WANG Chang-Yun LIU Hai-Yan SUN Xue-Ping LI Xiu-Bao ZHENG Cai-Juan HAN Lei SHAO Chang-Lun GUAN Hua-Shi |
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| Institution: | 1.Key Laboratory of Marine Drugs;Ministry of Education;School of Medicine and Pharmacy;Ocean University of China;Qingdao 266003;China;2.South China Sea Institute of Oceanology;Chinese Academy of Sciences;Guangzhou 510000;China |
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| Abstract: | The allelopathic effects of the ethanol extract and its organic fractions of a soft coral Sinularia sp.from the South China Sea were evaluated by the model of lethality to brine shrimp Artemia salina and cytotoxicity.It indicated that the allelopathic substances were mainly in the petroleum ether fraction.The components in the petroleum ether fraction were analyzed by GC/MS,and 15 compounds were identified,most of which were lipids and steroids.From the sterol component(SC-P-1) isolated from petroleum ether... |
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| Keywords: | soft coral Sinularia sp allelopathic effects sterols GC/MS |
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