解郁安神法联合体外反搏对PCI术后气滞血瘀型胸痹患者的临床疗效观察

目的：观察解郁安神法联合体外反搏（EECP）对经皮冠状动脉介入治疗（PCI）术后气滞血瘀型胸痹患者的临床疗效。方法：将80例冠心病PCI术后气滞血瘀型胸痹患者随机分为治疗组和对照组,每组各40例。对照组采用PCI术后规范化治疗,同时联合EECP治疗;治疗组在对照组基础上加服解郁安神方治疗,随访观察7周,比较2组临床证候疗效、Zung焦虑自评量表（SAS）评分、抑郁自评量表（SDS）评分、西雅图心绞痛调查量表（SAQ）评分。结果：总有效率治疗组为82.5%（33/40）,高于对照组的60.0%（24/40）,2组比较,差异有统计学意义（P<0.05）;2组SAS、SDS、SAQ评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义（P<0.05）。结论：解郁安神法联合EECP治疗可明显改善PCI术后气滞血瘀型胸痹患者的临床症状,缓解焦虑抑郁程度,提高患者生活质量,值得临床推广应用。     

传统海图和电子海图一体化数据模型的构建与应用研究

针对国内在一定时期内既要生产传统纸质海图保证传统导航,又要生产电子海图满足电子导航的需求,构建了一个能够包容S-57电子海图和传统海图信息全集的一体化海图数据模型,基于此模型分析了两种数据到一体化数据模型的转换机制,并应用此模型开发原型系统,实现了二者之间的一体化组织和切换显示,为探索传统海图和电子海图的数据融合提供了思路和参考。     

全球不同构造环境蛇纹岩全岩和矿物微量元素组成及非传统稳定同位素(Fe- Zn- Cu同位素)特征

蛇纹岩对地球深部和浅部的元素循环以及氧化还原状态调节具有非常重要的作用。蛇纹岩中的流体活动性元素(fluid- mobile element, FME)是揭示地幔岩石水化、脱水以及元素循环的关键。本文系统收集和分析了前人报道的不同构造环境的蛇纹岩矿物化学、全岩微量元素和非传统稳定同位素(Fe、Zn、Cu)的组成特征，试图从多个角度总结蛇纹岩脱水过程的元素迁移规律及流体性质。蛇纹岩主要矿物蛇纹石微量元素含量具有以下主要特征：① 不同变质程度的蛇纹岩中的蛇纹石既包含轻稀土元素(light rare earth element, LREE)富集，又包含LREE亏损的特征；② 纤蛇纹石的REE和微量元素分布在利蛇纹石和叶蛇纹石的范围内，利蛇纹石重稀土元素(heavy rare earth element, HREE)整体上略高于叶蛇纹石且更加富集FME；③ 通过中度不相容元素与REE含量相结合，能够较好地区分橄榄石和辉石蛇纹石化所形成的蛇纹石，即辉石形成的蛇纹石富集相容元素(如Sc、Zn、Cr、Y和Ti等)并具有较高的HREE，而橄榄石形成的蛇纹石则表现为平坦且整体较低的REE分布型式。在蛇纹岩全岩微量元素和稀土元素(rare earth element, REE)含量方面，不同构造环境的蛇纹岩具有较大范围的重叠，但也有一定的差异：① 慢速扩张的印度洋中脊蛇纹岩REE和微量元素含量要整体高于快速扩张的大西洋中脊和太平洋中脊的蛇纹岩；② 马里亚纳蛇纹岩泥相比于蛇纹岩和蛇纹石化纯橄岩具有更高的REE和微量元素，而蛇纹石化纯橄岩相比于蛇纹岩则具有相对低的REE及流体不活动性元素含量。因此，利用微量元素的含量在区分不同环境的蛇纹岩方面存在一定的困难。但是，碱金属元素与U元素含量及其相应的比值，则可以较明显区分出大洋蛇纹岩和弧前蛇纹岩。目前已发表的蛇纹岩Fe、Zn、Cu同位素数据表明：① 蛇绿岩中的蛇纹岩Fe和Zn同位素的分馏与其变质程度密切相关。蛇纹岩在进变质过程中δ 56Fe值与Fe 3+/∑Fe值呈负相关，而Zn含量和δ 66Zn值则呈现正相关，表明蛇纹岩变质脱水能够释放氧化性流体；② 与橄榄岩相比，蛇纹岩具有明显低的δ 65Cu值，表明橄榄岩蛇纹石化过程中存在氧化性流体的加入。蛇纹岩Fe、Zn、Cu同位素在示踪流体性质和氧化还原状态方面有很大潜力，对壳幔系统的化学循环具有重要意义。     

无验潮模式下的GPS水下地形测量技术

传统的水下地形测量模式定型于利用GPS测定水底点的平面位置,利用测深仪测定水底点的深度,附之以瞬时潮位资料,获得点位的高程。这种模式在上述条件具备的情况下,可取得完满的结果。但当验潮条件不具备时,该模式将不能获得测点的高程。为了弥补这一缺陷,简化工作流程,提高水下地形测量的精度,本文提出了一种无验潮模式下的水下地形测量思想,该思想不用专门测定潮位,而直接利用GPS的RTK测量技术,辅之以姿态测量和补偿,从而获得高精度的水底点高程。该方法被验证是正确的,希望进一步推广应用。     

Problems of the solution: intervention into small-scale irrigation for drought proofing in the Mekele Plateau of northern Ethiopia

The Mekele Plateau, located in the semi-arid northern highland region of Ethiopia, is a drought-prone, highly degraded area. It has long been neglected by policymakers and thus recurring famine, widespread poverty, armed conflicts and mass outmigration have contributed to the near collapse of the farming systems and the livelihoods of the population. Traditional stream diversion irrigation has been practised in this area for several centuries. The systems of water management in particular may be considered inappropriate owing to the need for thriftiness in water use imposed by the local environment. The systems of headworks and canals are crude and wasteful on water. Recent interventions to improve the small-scale irrigation systems of the area have not been successful. Most interventions have preferred to introduce rainwater harvesting systems using micro-dams rather than trying to upgrade the traditional diversion schemes. Evaluation of irrigation structures in the field, interviews with key informants in government, analysis of documents and discussions with irrigators indicate that both the Ministry of Agriculture and SAERT-Commission's rainwater harvesting programmes have generally failed. The case of the most recent intervention by SAERT has failed because of myopic project planning, inadequate engineering studies, unsound designs, too short a time for implementation, and lack of full farmer involvement at different levels of project planning and implementation.     

三香通络饮联合苯磺酸氨氯地平片治疗老年性高血压病46 例临床观察

目的：观察三香通络饮联合苯磺酸氨氯地平片治疗老年性高血压病的临床疗效。方法：将92 例老年性高血压病患者按随机数字表法分为治疗组和对照组,每组各46 例。对照组口服苯磺酸氨氯地平片治疗,治疗组在对照组基础上加用三香通络饮治疗。比较2组的综合疗效、中医证候积分及不良反应发生情况。结果：总有效率治疗组为89.13%（41/46）,对照组为60.87%（28/46）,2组比较,差异有统计学意义（P<0.05）;2组各项中医证候积分治疗前后组内比较,差异均有统计学意义（P<0.05）,且治疗后头晕目眩、头痛、心悸、口干口苦评分组间比较,差异均有统计学意义（P<0.05）;不良反应发生率治疗组为10.87%（5/46）,对照组为19.57%（9/46）,2组比较,差异无统计学意义（P>0.05）。结论：三香通络饮联合苯磺酸氨氯地平片治疗老年性高血压病患者的临床疗效优于单用西药治疗,且能有效减轻临床症状,值得推广。     

健脾柔肝息风汤对抽动障碍模型大鼠行为学及多巴胺受体mRNA表达的影响

目的：探讨健脾柔肝息风汤对抽动障碍模型大鼠运动性抽动的调节机制,为临床治疗抽动障碍提供实验依据。方法：将60只SD大鼠随机分为空白组,模型组,氟哌啶醇组,健脾柔肝息风汤低、中、高剂量组,每组各10只,除空白组外各组大鼠连续7 d腹腔注射亚氨基二丙腈（IDPN）造模,造模成功后连续灌胃6周,灌胃后第1、3、6周分别观察大鼠的行为学改变,采用RT-PCR法检测大鼠脑组织DRD1 mRNA、DRD2 mRNA含量。结果：灌胃6周后,与模型组比较,健脾柔肝息风汤中、高剂量组及氟哌啶醇组在运动行为评分、刻板行为评分及DRD1 mRNA含量方面均有所下降（P<0.05）;而健脾柔肝息风汤低、中、高剂量组及氟哌啶醇组在DRD2 mRNA含量方面有所下降（P<0.05）。结论：健脾柔肝息风汤可通过降低TD模型大鼠脑组织多巴胺DRD1 mRNA、DRD2 mRNA的含量,而改善TD模型大鼠运动性抽动行为。     

Groundwater recharge sources in semiarid irrigated mountain fronts

High-elevation mountains often constitute for basins important groundwater recharge sources through mountain-front recharge processes. These processes include streamflow losses and subsurface inflow from the mountain block. However, another key recharge process is from irrigation practices, where mountain streamflow is distributed across the irrigated piedmont. In this study, coupled groundwater fluctuation measurements and environmental tracers (¹⁸O, ²H, and major ions) were used to identify and compare the natural mountain-front recharge to the anthropogenically induced irrigation recharge. Within the High Atlas mountain front of the Ourika Basin, Central Morocco, the groundwater fluctuation mapping from the dry to wet season showed that recharge beneath the irrigated area was higher than the recharge along the streambed. Irrigation practices in the region divert more than 65% of the stream water, thereby reducing the potential for in-stream groundwater recharge. In addition, the irrigation areas close to the mountain front had greater water table increases (up to 3.5 m) compared with the downstream irrigation areas (<1 m increase). Upstream crops have priority to irrigation with stream water over downstream areas. The latter are only irrigated via stream water during large flood events and are otherwise supplemented by groundwater resources. These changes in water resources used for irrigation practices between upstream and downstream areas are reflected in the spatiotemporal evolution of the stable isotopes of groundwater. In the upstream irrigation area, the groundwater stable isotope values (δ¹⁸O: −8.4‰ to −7.4‰) reflect recharge by the diverted stream water. In the downstream irrigation area, the groundwater isotope values are lower (δ¹⁸O: −8.1‰ to −8.4‰) due to recharge via the flood water. In the nonirrigation area, the groundwater has the highest stable isotope values (δ¹⁸O: −6.8‰ to −4.8‰). This might be due to recharge via subsurface inflow from the mountain block to the mountain front and/or recharge via local low altitude rainfall. These findings highlight that irrigation practices can result in the dominant mountain-front recharge process for groundwater.     

痛泻要方对溃疡性结肠炎患者中医证候及肠道菌群的影响

目的：观察痛泻要方对溃疡性结肠炎（UC）肝郁脾虚证的临床疗效及其对肠道菌群的影响。方法：将40例UC肝郁脾虚证患者随机分为治疗组和对照组,每组各20例。对照组予美沙拉嗪肠溶片治疗,治疗组在对照组基础上加用痛泻要方治疗。2组疗程均为12周,比较2组治疗前后中医证候积分及肠道菌群的变化。结果：治疗前,2组中医证候积分、主要肠道菌群数目比较,差异无统计学意义（P＞0.05）。与治疗前比较,治疗后2组中医证候积分均降低,有益菌群（双歧杆菌、乳酸杆菌）数目均明显上升,而有害菌群（大肠埃希菌）数目明显下降,且治疗组的指标改善情况均优于对照组,差异有统计学意义（均P<0.05）。结论：痛泻要方可有效改善UC肝郁脾虚证患者的中医证候,纠正患者肠道菌群的紊乱,提高临床疗效。     

中国东部7类暴雨异常环流型

近年来的研究发现,瞬变扰动天气图上的扰动场天气系统对区域暴雨的落区指示能力强于传统天气图上的总场天气系统。为供预报员在业务预报中参考,本文划分1998年发生在中国东部地区的41日次区域暴雨为7类扰动场天气系统。与区域暴雨相联系的7类异常环流型分别是:华南切变线、华南涡旋、华南倒槽、长江切变线与槽、沿江涡旋、华北涡旋和东北涡旋。无论是在对流层的垂直剖面上,还是在850 hPa水平分布上,扰动天气图上位势高度低值和风扰动辐合处并配合大的水汽扰动对应有区域暴雨,而传统天气图上的低值系统和高水汽区与暴雨之间存在位置上的偏移。由此建议,用实况大气变量和中期数值模式产品绘制扰动天气图有助于预报员确定区域暴雨落区。