胃复方的急性毒性实验研究

目的：对胃复方进行急性毒性实验研究，观察其安全性。方法：将实验小鼠按体质量随机分为2组，采用最大给药量法测定小鼠口服胃复方的最大耐受量，给药组24h内2次以最大浓度、最大体积的中药胃复方给予小鼠灌胃，对照组小鼠灌服等剂量蒸馏水，观察记录2组小鼠一般情况及死亡情况，对主要脏器进行病理组织学检测。结果：给药组小鼠一般情况良好，无1例死亡。与对照组比较，体质量变化差异无统计学意义（P>0.05）；主要脏器病理组织学检测未见明显异常；最大给药量为221.7g生药/kg，相当于60kg成人临床推荐剂量的127倍。结论：胃复方无明显毒性，在规定剂量下用药是安全可靠的。     

基于肌肉量和体脂率探讨中老年2型糖尿病与脾虚的关系

目的：探讨中老年2型糖尿病患者肌肉量减少、体脂率肥胖与脾虚的关系，并以此为从脾论治中老年2型糖尿病提供临床依据。方法：采用病例对照研究方法，随机选取≥50岁的2型糖尿病住院患者100 例为研究对象，其中男、女各50 例，按照相关标准辨证分为脾虚组和非脾虚组。对研究对象进行生物电阻抗（BIA）、体脂率（PBF）、肌肉量检测和生化指标检验。结果：不同性别在脾虚组与非脾虚组中PBF、骨骼肌指数（ASMI）之间分别存在差异，且差异具有统计学意义（P＜0.05）。以量表评分的高低评估脾虚的程度，不同性别存在差异，男性主要表现为骨骼肌含量减少，与量表评分呈负相关性，女性则以体脂率的增加为主，与量表评分呈正相关性。男性≥70岁者有出现肌肉量减少伴体脂率高的肌少性肥胖倾向。在体脂率及骨骼肌质量中，存在相互依存关系，表现为脂肪组织对肌肉的保护作用。结论：中老年2型糖尿病患者肌肉量减少、体脂率肥胖均与脾虚相关，从脾论治是一个可行的思路。     

Smectite formation in metalliferous sediments near the East Pacific Rise at 13°N

A 43 cm long E271 sediment core collected near the East Pacific Rise(EPR) at 13°N were studied to investigate the origin of smectite for understanding better the geochemical behavior of hydrothermal material after deposition.E271 sediments are typical metalliferous sediments. After removal of organic matter, carbonate, biogenic opal,and Fe-Mn oxide by a series of chemical procedures, clay minerals(2 μm) were investigated by X-ray diffraction,chemical analysis and Si isotope analysis. Due to the influence of seafloor hydrothermal activity and close to continent, the sources of clay minerals are complex. Illite, chlorite and kaolinite are suggested to be transported from either North or Central America by rivers or winds, but smectite is authigenic. It is enriched in iron, and its contents are highest in clay minerals. Data show that smectite is most likely formed by the reaction of hydrothermal Fe-oxyhydroxide with silica and seawater in metalliferous sediments. The Si that participates in this reaction may be derived from siliceous microfossils(diatoms or radiolarians), hydrothermal fluids, or detrital mineral phases. And their δ30 Si values are higher than those of authigenic smectites, which implies that a Si isotope fractionation occurs during the formation because of the selective absorption of light Si isotopes onto Feoxyhydroxides. Sm/Fe mass ratios(a proxy for overall REE/Fe ratio) in E271 clay minerals are lower than those in metalliferous sediments, as well as distal hydrothermal plume particles and terrigenous clay minerals. This result suggests that some REE are lost during the smectite formation, perhaps because their large ionic radii of REE scavenged by Fe-oxyhydroxides preclude substitution in either tetrahedral or octahedral lattice sites of this mineral structure, which decreases the value of metalliferous sediments as a potential resource for REE.     

基于航海应用的海图数据库比例尺分级研究

介绍了我国海图生产现状及基于数据库的海图制图技术,针对以航海图生产为主要目的的海图数据库建设中的比例尺分级问题,依据统一的样本海图选择原则,计算海部要素载负量,计算结果表明,海图载负量数值受地形、人为等因素影响大。定义一个全水深的理想海部区域,通过确定水深注记间距和载负量之间的关系、参考现有海图水深注记最小间距值和航海应用对海图比例尺分级的需求等因素,最终确定了海图数据库比例尺分级方案。     

高中地理优质课中的师生对话研究--以“大规模的海水运动”为例

本研究采用"同课异构"的研究思路,从"2015年全国地理教学研究会优质课比赛"获奖的视频课例中选取四节"大规模的海水运动"课作为样本,对四节高中地理优质课中的师生对话进行定性和定量相结合的比较研究。得出研究结论:四节课中师生对话频繁,课堂氛围活跃,但师生对话在认知水平、对话结构、师生话语权等方面存在巨大差异。这些差异将对地理核心素养的落实产生不同影响。     

湘中煤层含气性及其变化特征

湘中主要赋存有下石炭统测水组、上二叠统龙潭组、上三叠统安源组和下侏罗统造上组等煤系。湘中煤层气含量主要是受煤级、煤层埋深、构造运动、围岩、水文地质条件因素的影响。     

超基性岩中含铜、钴块状硫化物矿床——德尔尼铜矿成因新认识

长期以来对德尔尼铜矿的成因存在着不同认识。从矿石组成和结构、构造来看,应属典型的块状硫化物矿石,矿床亦应属于含铜黄铁矿型矿床。但从其地质产状来看又与一般的黄铁矿型矿床大不相同,与一般的岩浆熔离铜镍硫化物矿床也有较多差异。这就是本矿床类型独特之处。近年来通过工作又取得一些新资料,特别是超基性岩和矿石的同位素年龄数据。本文在综合新老资料基础上,提出新看法,认为该矿床形成于上地幔,再就位于地壳浅部。其成因类型暂定为:“深部熔离—构造侵位矿床”。鉴于本矿床与一般块状硫化物矿床相比有其独特性,建议命名为“德尔尼型”。