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71.
多氯联苯(Aroclor 1242)胁迫下鲤鱼肝脏组织氧化应激   总被引:1,自引:0,他引:1  
本文在实验室条件下通过静态水质染毒方式在生理生化和转录水平上探究了我国重要经济鱼种鲤鱼(Cyprinus carpioio)对多氯联苯Aroclor 1242的氧化应激:鲤鱼肝脏组织抗氧化酶[超氧化物歧化酶(SuperoxideDismutase,SOD)和过氧化氢酶(Catalase,CAT)]活性、脂质过氧化产物丙二醛(Malonydialdehyde,MDA)含量、相关抗氧化酶编码基因(Cu/Zn-SOD、Mn-SOD、CAT)、应激蛋白HSP70、转录因子Nrf2和芳烃受体AhR2基因表达。结果表明:Aroclor 1242胁迫下,鲤鱼肝脏组织抗氧化酶活性表现出低浓度促进高浓度抑制的趋势;肝脏组织丙二醛含量显著升高,其中390μg/L暴露组鲤鱼肝脏组织MDA含量在第6d高于对照组92.1%(P0.01),表明肝脏组织发生脂质过氧化,膜系统受到损伤;鲤鱼肝脏组织中Cu/Zn-SOD、Mn-SOD、CAT、HSP70、Nrf2和AhR2编码基因表达出现不同程度下调。本文从酶学和基因转录水平上揭示了Aroclor1242胁迫下鲤鱼肝脏组织细胞的氧化应激。  相似文献   
72.
Floating wind turbine has been the highlight in offshore wind industry lately. There has been great effort on developing highly sophisticated numerical model to better understand its hydrodynamic behaviour. A engineering-practical method to study the nonlinear wave effects on floating wind turbine has been recently developed. Based on the method established, the focus of this paper is to quantify the wave nonlinearity effect due to nonlinear wave kinematics by comparing the structural responses of floating wind turbine when exposed to irregular linear Airy wave and fully nonlinear wave. Critical responses and fatigue damage are studied in operational conditions and short-term extreme values are predicted in extreme conditions respectively. In the operational condition, wind effects are dominating the mean value and standard deviation of most responses except floater heave motion. The fatigue damage at the tower base is dominated by wind effects. The fatigue damage for the mooring line is more influenced by wind effects for conditions with small wave and wave effects for conditions with large wave. The wave nonlinearity effect becomes significant for surge and mooring line tension for large waves while floater heave, pitch motion, tower base bending moment and pontoon axial force are less sensitive to the nonlinear wave effect. In the extreme condition, linear wave theory underestimates wave elevation, floater surge motion and mooring line tension compared with fully nonlinear wave theory while quite close results are predicted for other responses.  相似文献   
73.
For civil engineering structures with a tightness role, structural permeability is a key issue. In this context, this paper presents a new proposition of a numerical modelling of leakage rate through a cracked concrete structure undergoing mode I cracking. The mechanical state of the material, considered in the framework of continuum mechanics based on finite element modelling, is described by means of the stress‐based nonlocal damage model which takes into account the stress state and provides realistic local mechanical fields. A semi‐discrete method based on the strong discontinuity approach to estimate crack opening is then considered in the post‐treatment phase. Using a Poiseuille's like relation, the coupling between the mechanical state of the material and its dry gas conductivity is performed. For validation purposes, an original experimental campaign is conducted on a dry concrete disc loaded in a splitting setup. During the loading, gas conductivity and digital image correlation analysis are performed. The comparison with the 3D experimental mechanical global response highlights the performance of the mechanical model. The comparison between crack openings measured by digital image correlation and estimated by the strong discontinuity method shows a good agreement. Finally, the results of the semi‐discrete approach coupled with the gas conductivity compared with experimental data show a good estimation of the structural conductivity. Consequently, if the mechanical problem is well modelled at the global scale, then the proposed approach provides good estimation of gas conductivity. Copyright © 2016 John Wiley & Sons, Ltd.  相似文献   
74.
The present paper focuses on selected plasticity and damage‐plasticity models for describing the 3D material behavior of concrete. In particular, a plasticity model and a damage‐plasticity model are reviewed and evaluated. Based on the results of the evaluation, enhancements are proposed, aiming at improving the correspondence between predicted and observed material behavior and aiming at implementing a robust and efficient stress update algorithm in a finite element program for performing large‐scale 3D numerical simulations of concrete structures. The capabilities of the concrete models are demonstrated by 3D numerical simulations of benchmark tests with combined bending and torsional loading and combined compression and shear loading and by a large‐scale 3D finite element analysis of a model test of a concrete arch dam. Copyright © 2011 John Wiley & Sons, Ltd.  相似文献   
75.
区域生态风险评价是对各种生态风险及环境问题进行评价和管理的重要手段。针对雅安地震灾区特殊的自然地理及生态环境特征,选取芦山县为研究对象,采用遥感、GIS及SPSS统计分析的方法,通过风险源、风险受体、暴露和易损性分析,建立生态风险综合评价模型,划分生态风险区类型,进而提出生态风险管理对策。结果表明:1)微度和低度生态风险区集中分布在高海拔的森林及草地生态系统,该区生物多样性丰富,抗干扰能力较强,地质灾害及人类活动影响较小;2)中度和高度生态风险区具有沿农田及建设用地生态系统集聚分布的特征,该区地质灾害频繁,地壳活动性较强,生态系统抵抗灾害的能力较差。研究结果可为地震灾区防御、规避风险及安全选址提供科学依据。  相似文献   
76.
This paper aims at developing a method for modeling rock mass with preexisting multiple discontinuities within the framework of the smoothed finite element method (SFEM). The discontinuity is simulated by an interface element with zero thickness, the stiffness matrix of which are derived explicitly based on the SFEM. An elastic damage constitutive relation with residual strength is introduced in order to describe the nonlinear mechanical behavior of the discontinuities. The computation codes of the present method were developed. The present method has been verified to be a sound approach for modeling discontinuous rock mass, inheriting the advantages of the SFEM.  相似文献   
77.
2015年6月1日21:30左右长江湖北监利段发生"东方之星"客轮翻沉特大事故。本文根据事发周边陆地区域现场天气调查结果,结合卫星和雷达观测资料分析认为,6月1日21:00-21:40左右事发江段和周边区域发生了下击暴流导致的强烈大风灾害,最强风力超过12级,并具有空间分布不连续、多尺度和强灾害时空尺度小等特征。事发周边区域北部受中气旋影响陆地区域(顺星村、老台深水码头、四台村养猪场附近、新沟子养鸡场附近等)灾情较南部阵风锋及其后侧下击暴流影响的陆地区域更为显著。综合雷达观测资料和现场调查资料分析判断多数调查点灾害为显著微下击暴流所致,其中老台深水码头有龙卷发生的可能。导致此次风灾的强对流风暴气流具有显著的多尺度性;事发周边区域北部的四台村养猪场附近树林中同时发生了多条相邻的微下击暴流条迹,呈现出辐散和辐合交替分布的特征,展示了此次强对流风暴中大气运动的复杂分布特点。虽然下击暴流会伴随中小尺度的涡旋特征,但此次现场调查发现的与下击暴流相联系的辐合特征水平尺度仅几十米,远小于弓形回波两端的书挡涡旋或者中涡旋等几千米级的水平尺度。  相似文献   
78.
杨若子  周广胜 《气象科学》2016,36(3):311-318
基于东北三省1961-2013年气象数据,结合具有生物学意义的热量指数,利用SPSS聚类分析方法给出了东北三省低温冷害分类标准,并对低温冷害频率时空特征和年代际空间变化规律进行了分析。研究指出:东北三省玉米(轻、中、重度)低温冷害发生范围随时间呈减小-增大-减小变化趋势,1999年后东北三省出现低温冷害的范围显著减小,变化幅度均为中度> 重度> 轻度低温冷害。近10 a东北三省的轻度低温冷害仍时有发生,而中度和重度低温冷害发生较少。东北三省低温冷害频率呈由北向南呈减小趋势,轻、中、重度低温冷害频率高值区分别位于营口、哈尔滨和大兴安岭地区。各年代的重度低温冷害发生范围变化不大,中度与轻度低温冷害发生范围变化较大。研究结果可为东北三省低温冷害风险评估提供依据。  相似文献   
79.
富春江顶管工程为例,介绍了一种可快速拆卸的用于深埋顶管隧道对管节局部破损进行修复的装置。装置结构简单、紧凑,易于在圆形截面的隧道中进行快速拼装。该装置最高耐水压力0.8 MPa,可对地下水位以下30~80 m顶管隧道中出现沿轴线长<0.4 m环状破损的管节进行注浆修复。这种设计能够有效解决深埋顶管隧道小面积局部破损、小范围漏水涌砂等问题,为深埋顶管等方法构筑的圆形隧道提供应急修复保障。  相似文献   
80.
In jacket-type offshore structures, corrosion damage affects the structural performance under compressive loading, which is created by the working and design loads of the main system. In this study, the effects of corrosion damage on the compressive structural behavior and strength of steel tubular members were investigated. Artificial corrosion damage was applied to the tubular specimens via mechanical processing and hand drilling to replicate the inclined nature of jacket-type offshore structures. The damage was applied to either half or all of the circumference of the specimens. The compressive failure modes of the artificially corroded tubular members were affected by the corrosion conditions. The compressive strengths were also affected by the level of corrosion. From the results of this study, the residual compressive strengths of corroded tubular steel members can be estimated based on the condition of the damaged sectional areas.  相似文献   
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