Fatal attraction: synthetic musk fragrances compromise multixenobiotic defense systems in mussels

We studied interactions of nitromusk compounds musk ketone and musk xylene and polycyclic musks Galaxolide trade mark (HHCB), Celestolide trade mark (ADBI), Tetralide trade mark (AHTN), and Traseolide trade mark (AITI) with multixenobiotic resistance (mxr) transporters in gill tissue of the marine mussel Mytilus californianus (Conrad, 1837). A competitive substrate transport test with rhodamine B was used to assay modulation of transport activity by musks. All tested musks inhibited the transport activity in the low microm range as indicated by increased accumulation of rhodamine B in the tissue. Compared to known substrates of mxr transporters, the effective concentration range was similar to quinidine and about 100 times higher than verapamil. Musk ketone and musk xylene also inhibited efflux of rhodamine B from gill tissue which was loaded with the dye and subsequently incubated with these compounds. Synthetic musk compounds are persistent environmental pollutants in aquatic environments with a high potential to bioaccumulate. As potent inhibitors of mxr transporters they may also play a role as chemosensitizers that enable toxic mxr substrates to accumulate in cells of aquatic organisms.     

先锋孤立子生成的理论平均波阻(Ⅰ).理论

根据作者导得的AfKdV方程，理论上确定了先锋孤立子生成问题的理论平均波阻，能量劈分及能量劈分比。本文的能量劈分是确定先锋孤立子生成参数的理论基础。同时，本理论确定了现有理论中的自由未知参数问题，从而使先锋孤立子生成参数得到理论预报。     

The Working Mechanism and An Analytic Method of the Deep Embedded Large Cylinder Structure

The large cylinder is a new-type structure that has been applied to harbor and offshore engineering. An analytic method of the relationship between loads and the structure displacement is developed based on the failure mode of deep embedded large cylinder structures. It can be used to calculate directly the soil resistance and the ultirnate bearing capacity of the structure under usage. A new criterion of the large cylinder structure, which discriminates the deep embedded cylinder from the shallow embedded cylinder, is defined. Model tests prove that the proposed method is feasible for the analysis of deep embedded large cylinder structures.     

1999年以来台湾及邻近海域7.5级以上强震前的条带现象

中国台湾地区地处欧亚板块与菲律宾海板块之间,地震活动频繁．本文报道了 我国台湾地区及其邻近海域1985～2002年间5．5级以上地震的条带内外频度比分 布,并着重研究了1999—2002年中发生的3次7．5级以上地震前的条带现象．其结 果表明:台湾地区近期发生的3次7．5级以上大地震前,5．5级以上地震呈条带分 布．这些条带符合条带内地震个数Nin≥6的条件,符合条带内、外频度比Nin／(Nin Nout)≥75％的条件,也符合条带长宽比大于5的要求,只是与板内地震条带相比,条 带的长度较短．     

Change of multifractal thermal characteristics in the western Philippine sea upper layer during internal wave-soliton propagation

The upper layer (above 140 m depth) temperature in the western Philippine Sea near Taiwan was sampled using a coastal monitoring buoy (CMB) with 15 attached thermistors during July 28–August 7, 2005. The data were collected every 10 min at 1, 3, 5, 10, 15, and 20 m using the CMB sensors, and every 15 sec at 15 different depths between 25 m and 140 m. Internal waves and solitons were identified from the time-depth plot of the temperature field. Without the internal waves and solitons, the power spectra, structure functions, and singular measures (representing the intermittency) of temperature field satisfy the power law with multi-scale characteristics at all depths. The internal waves do not change the basic characteristics of the multifractal structure. However, the internal solitons change the power exponent of the power spectra drastically, especially in the low wave number domain; they also break down the power law of the structure function and increase the intermittency parameter. The physical mechanisms causing these different effects need to be explored further.     

On the estimation of mooring line characteristic resistance for reliability analysis

The main aim of this work is to derive a correct formulation for the characteristic resistance of a mooring line segment with lognormally distributed component resistances and substitute an equation proposed by Vazquez-Hernandez et al. [Vazquez-Hernandez AO, Ellwanger GB, Sagrilo LVS. Reliability-based comparative study for mooring lines design criteria. Appl Ocean Res 2006; 28(6):398–406] in a paper published in this journal, which is not correct. The mooring line is considered as a series system and the resistances of individual components of a line segment are statistically independent and identically distributed; furthermore, the case of normally distributed component resistances is also discussed. A comparison with the corresponding equation proposed by DNV-OS-E301 is given. Results show that the formula proposed by Vazquez-Hernandez et al. [Vazquez-Hernandez AO, Ellwanger GB, Sagrilo LVS. Reliability-based comparative study for mooring lines design criteria. Appl Ocean Res 2006; 28(6):398–406] overestimates quite significantly the characteristic resistance of a mooring line segment.     

1994年发生在台湾海峡的一次地震海啸的数值模拟

建立了一个地震海啸数值模式,模式包含越洋海啸传播部分和近岸海啸变形部分,在越洋海啸传播部分中采用线性浅水方程,使用蛙跃格式求解,并且选择合适的空间步长与时间步长,使差分格式中产生的数值频散与包辛尼斯克方程中的物理频散一致,这样在不影响海啸数值计算精度的前提下,节省了计算机的机时与内存.在近岸海啸变形部分的计算中,考虑了非线性对流项与海底摩擦项.同时该模式采用了多重网格嵌套技术,提高了所关心地区的计算精度.利用这个地震海啸模式模拟了1994年发生在台湾海峡的一次地震海啸,结果与观测记录较吻合.这个模型已用于我国沿海核电站可能最大地震海啸的数值计算.     

减少航道外波浪集聚对策研究

进港航道开挖引起波能重新分布 ,导致航道外近区域波能聚集 ,波高增大 ,从而影响防波堤稳定及港内泊稳条件。文章介绍了 Boussinesq方程的推导过程和发展过程 ,基于深水和缓变地形的色散关系 ,建立了波浪数学模型。该模型可用于研究深水和浅水地区波浪的浅水变形、折射、绕射和反射。并提出了减少波能聚集、降低堤前波高的多种措施。结合大窑湾港实际工程 ,经过多方面的数物模比选 ,利用数学模型优化出一种可行的喇叭口航道开挖方案并付诸实施 ,降低了防波堤的堤前波高 ,满足了预期的设计要求。     

深海资料浮标体及系泊系统的阻力试验研究

本文结合国家“七五”重点科技攻关项目“深海资料浮标”研制而进行浮标体和系泊系统的各种阻力试验研究，试验成果已直接应用于深海资料浮标系泊系统设计。实践表明本文介绍的各种阻力试验结果是可靠的。     

青岛胶州湾3.2级地震构造背景与控震断裂

本文应用构造分析的方法 ,对青岛胶州湾 3.2级地震发生的地震地质背景和构造背景进行分析。结果表明 :胶州湾 3.2级地震主要受 NEE向郝官庄断裂和 NNW向大沽河断裂控制 ,并根据现代活动断裂的标志 ,对上述 2组断裂活动性特征作了阐述