CT肝脏灌注临床应用研究进展

CT灌注成像是一种通过计算单位时间每体素内对比剂浓度改变,从而反映组织、器官血流动力学变化的无创性功能成像技术。在疾病的诊断、鉴别诊断及疗效评估中具有重要价值。目前,CT灌注技术在中枢、上腹脏器中的应用最为广泛,腹部以肝脏灌注技术最为成熟。多种肝脏病变鉴别诊断困难、治疗与预后差异较大,CT灌注为正确评估肝脏病变提供了新方法和新思路。本文现就CT肝脏灌注的原理、优势及临床价值等方面予以综述。      

The influence of tectonic subsidence on volcaniclastic sedimentation: The Cretaceous upper Daeri Member,Wido Island,Korea

The Daeri Member, a Cretaceous volcanic–sedimentary succession, can be divided into lower, middle, and upper parts based on vertical changes in its lithologic characters. The lower Daeri Member is composed of siliciclastic deposits formed in a semi‐arid floodplain environment, which is overlain by the middle Daeri Member consisting mainly of andesite lava flow. After the emplacement of the andesite, activities of intrabasinal normal faults created accommodation on hanging wall blocks together with the development of intrabasinal topographic relief. The upper Daeri Member occurs only in hanging wall blocks and is composed of rhyolitic volcaniclastic sediments formed during an explosive volcanic eruption. Following the eruption, owing to semi‐arid climatic conditions and the destruction of vegetation, the eruptive materials were easily remobilized and deposited by episodic sediment gravity flows, resulting in deposition of the resedimented volcaniclastic deposits with sheet‐like geometry. Away from the intrabasinal normal faults, the resedimented volcaniclastic deposits show a decrease in grain size together with changes in inferred depositional processes from debris flows to hyperconcentrated flows and supercritical sheetfloods. This suggests that the resedimented volcaniclastic deposits were stacked on alluvial fan environments induced by intrabasinal topographic relief associated with normal fault activities. In addition, episodic movement of the faults gave rise to periodic fluctuation of the accommodation and an increase in gradient of the alluvial fan surface, resulting in the development of coarsening‐upward trends in the resedimented volcaniclastic deposits. The development of the alluvial fan and the coarsening‐upward trends indicate that dynamic tectonic subsidence and concomitant changes in the intrabasinal physiographic relief influenced the depositional processes and sizes of the transported volcaniclastic sediments of the upper Daeri Member. Thus, it is necessary to carefully observe tectonic signatures in volcaniclastic successions, particularly the syneruptive lithofacies, in order to reconstruct the tectonic and volcanic histories of receiving basins.     

Three-dimensional forward modeling of DC resistivity using the aggregation-based algebraic multigrid method

To speed up three-dimensional (3D) DC resistivity modeling, we present a new multigrid method, the aggregation-based algebraic multigrid method (AGMG). We first discretize the differential equation of the secondary potential field with mixed boundary conditions by using a seven-point finite-difference method to obtain a large sparse system of linear equations. Then, we introduce the theory behind the pairwise aggregation algorithms for AGMG and use the conjugate-gradient method with the V-cycle AGMG preconditioner (AGMG-CG) to solve the linear equations. We use typical geoelectrical models to test the proposed AGMG-CG method and compare the results with analytical solutions and the 3DDCXH algorithm for 3D DC modeling (3DDCXH). In addition, we apply the AGMG-CG method to different grid sizes and geoelectrical models and compare it to different iterative methods, such as ILU-BICGSTAB, ILU-GCR, and SSOR-CG. The AGMG-CG method yields nearly linearly decreasing errors, whereas the number of iterations increases slowly with increasing grid size. The AGMG-CG method is precise and converges fast, and thus can improve the computational efficiency in forward modeling of three-dimensional DC resistivity.     

来自海底高速层径向波的理论地震图研究

本文利用各向异性反射率技术计算理论地震图,提出海底高速薄层会产生沿高速层水平传播的波（简称径向波）,这种波在水层中作为P波,在固液界面激发下行横波,该均匀横波以临界角入射高速薄层,在层内作为超临界角的非均匀横波水平传播,再以临界角转换为上行传播的均匀横波,最终在固液界面上行透射转换为水层中P波.高速薄层传播的径向波不同于界面折射波,也不同于具有频散的面波和通道波.理论地震图的研究表明,径向波具有线性时距,能与海底强反射具有同等振幅水平;径向波有其振幅、时距位置和斜率这些观测记录参数,分别对应高速层的厚度、深度和近似的横波速度;径向波可以克服折射波解释中遇到的振幅强弱和高速层速度等困难.径向波可作为探测海底高速薄层的有力工具,对于研究高速层屏蔽、海底反射类型的多样性和相应的资料处理解释有重要意义.     

大功率高频电波加热电离层中人工沿场不均匀体散射特性的理论与数值模拟研究

大功率高频电波与电离层的相互作用会引起电子密度扰动,进而产生人工沿场不均匀体,其对无线电波特别是超短波信号有强的定向散射能力,可形成一种新型的超短波通信方式.基于各向异性介质的散射理论,首先通过求解电子密度扰动产生的附加极化势获得电子密度扰动散射方程,然后对电子密度扰动进行高斯自相关处理,并结合入射波/散射波与地磁场方向的空间几何关系,获得电子密度扰动的波数谱表达式,建立了人工沿场不均匀体的散射系数理论模型.利用模型对Platteville站实验中产生的人工不均匀体散射截面积进行了数值模拟,并通过与实测值对比验证了模型的正确性.根据人工沿场散射原理给出了利用其进行无线电信号传输的约束条件.重点仿真分析了人工沿场不均匀体的散射系数和散射覆盖区范围,结果表明：同等条件下,相对于高纬度地区,低纬度地区人工沿场不均匀体的散射系数小5~10 dB,但其散射覆盖区的地面范围大,东西向可达3000 km,南北向可达1500 km,完全可用于超短波信号的超远距离传输.本文结果为中低纬度地区开展相关实验研究提供了理论指导,对利用人工沿场不均匀体进行无线信号的超远距离传输应用研究具有重要意义.     

利用重复测线校正海空重力仪格值及试验验证

通过分析海空重力测量系统误差的形成机理,我们发现海空重力仪格值标定误差是引起系统性测量偏差的主要因素之一.本文简要介绍了重力仪格值的标定方法,分析论证了格值标定的精度要求,提出了利用东西正反向重复测线检测校正海空重力仪格值的计算模型和补偿方法,分析讨论了该方法的校正精度及其适用条件,利用航空重力实际观测网数据对该方法的合理性和有效性进行了数值验证,证明该方法对消除海空重力测量系统性偏差具有显著作用.     

基于BSWT-DDTFA方法的地球天然脉冲电磁场震前信号时频分析研究

地球天然脉冲电磁场（ENPEMF）信号,可理解为地球天然变化磁场的瞬间扰动,携带了大量有用的地质构造及其动力学信息.研究ENPEMF信号所蕴含的时间-频率联合分布特点,有利于深入了解目标对象的地球物理现象及其地质动力学原理.本文针对ENPEMF信号的非平稳特点,在数据驱动时频分析方法（DDTFA）的基础上提出了基于二值化同步压缩小波变换的改进算法（BSWT-DDTFA）.该算法可以实现数据驱动初始相位自动赋值的功能,具有自适应性.实验仿真和实际数据均证明了该改进算法不仅能够得到较为精确的频率曲线和更加清晰的时频分布,而且具有较强的抗噪声能力.以2013年芦山M_S7.0地震为例,利用BSWT-DDTFA方法提取ENPEMF信号的时频特性,结果表明ENPEMF信号的时间-频率-幅度分布在震前有明显的异常特征.     

鱼类形态特征与营养级位置之间关系初探

以长江中下游洪泛平原湖泊鱼类为例,探讨鱼类功能性形态特征与其营养级位置之间的关系.所用的116种鱼的食性数据来自于226个鱼类群落,总计16267尾鱼.用几何形态测量法的界标分析法提取鱼类形态特征,相对扭曲度法的前2个主成份能较好地区分鱼类的形态差异,它不仅能够生成散点图,而且能客观地反映出鱼类的形态性状.营养级位置采用肠含物定量分析法,合理地假定肠含物的营养级位置,利用食性数据计算出鱼类的营养级位置.采用广义加性模型分析鱼类营养级位置与功能性形态之间的关系.结果表明:只有当鱼类为植食性鱼类和肉食性鱼类才有特化的功能性形态与之相适应,植食性鱼类有较窄的口裂,而对肉食性鱼类而言,不同生活型的鱼类拥有各自特化的形态特征,如伏击型肉食性鱼类体型呈纺锤形,背鳍靠近头部,眼睛较大且靠上,头部面积较大;而追击型肉食性鱼类体型呈流线型,头部较小,背鳍和腹鳍靠近尾部.而杂食性鱼类在本研究中无更多证据证明有特化的外部形态,亟待进一步研究.     

三种裸腹溞的16S rDNA序列分析与系统分类探讨

为了检验已记录的3种裸腹溞(发头裸腹溞(Moina irrasa)、短型裸腹溞(Moina brachiata)、微型裸腹溞(Moina micrura))的系统分类,用试剂盒法分别提取3种裸腹溞的基因组DNA.利用特异性引物,通过PCR扩增了3种裸腹溞的16S r DNA部分序列,并与来自Gen Bank中每个种类相似度较高的裸腹溞属序列进行分析.结果表明,3种裸腹溞的平均种间相似度为88.7%,碱基中A+T含量均明显高于G+C含量.本研究的发头裸腹溞的16S r DNA序列与Gen Bank所下载的多刺裸腹溞(Moina macrocopa)的16S r DNA序列相似度为99%,遗传距离(K2P双参考模型)为0.5%,属种内范围;两个地区的短型裸腹溞测得的16S r DNA序列与Gen Bank下载的欧洲短型裸腹溞的16S r DNA序列序列相似度相对较低(88%~90%),遗传距离较大(13.2%~13.5%左右),已达到属内种间分化水平.基于16S r DNA构建的NJ树和贝叶斯树也支持以上结论.结果表明,本研究的发头裸腹溞可能为多刺裸腹溞,本研究用的短型裸腹溞与Gen Bank下载的欧洲短型裸腹溞已经达到种间分化的标准.由于缺乏物种形态资料和其他分子标记的对比,3种裸腹溞的分类地位还需进行更深入的探讨.     

SPATIAL AND TEMPORAL DISTRIBUTION OF SLIP RATE DEFICIT ACROSS HAIYUAN-LIUPAN SHAN FAULT ZONE CONSTRAINED BY GPS DATA

As the northeast boundary of the Tibetan plateau, the Haiyuan-Liupan Shan fault zone has separated the intensely tectonic deformed Tibetan plateau from the stable blocks of Ordos and Alxa since Cenozoic era. It is an active fault with high seismic risk in the west of mainland China. Using geology and geodetic techniques, previous studies have obtained the long-term slip rate across the Haiyuan-Liupan Shan fault zone. However, the detailed locking result and slip rate deficit across this fault zone are scarce. After the 2008 Wenchuan M_S8.0 earthquake, the tectonic stress field of Longmen Shan Fault and its vicinity was changed, which suggests that the crustal movement and potential seismic risk of Haiyuan-Liupan Shan fault zone should be investigated necessarily. Utilizing GPS horizontal velocities observed before and after Wenchuan earthquake(1999~2007 and 2009~2014), the spatial and temporal distributions of locking and slip rate deficit across the Haiyuan-Liupan Shan fault zone are inferred. In our model, we assume that the crustal deformation is caused by block rotation, horizontal strain rate within block and locking on block-bounding faults. The inversion results suggest that the Haiyuan fault zone has a left-lateral strike-slip rate deficit, the northern section of Liupan Shan has a thrust dip-slip rate deficit, while the southern section has a normal dip-slip rate deficit. The locking depths of Maomao Shan and west section of Laohu Shan are 25km during two periods, and the maximum left-lateral slip rate deficit is 6mm/a. The locking depths of east section of Laohu Shan and Haiyuan segment are shallow, and creep slip dominates them presently, which indicates that these sections are in the postseismic relaxation process of the 1920 Haiyuan earthquake. The Liupan Shan Fault has a locking depth of 35km with a maximum dip-slip rate deficit of 2mm/a. After the Wenchuan earthquake, the high slip rate deficit across Liupan Shan Fault migrated from its middle to northern section, and the range decreased, while its southern section had a normal-slip rate deficit. Our results show that the Maomao Shan Fault and west section of Laohu Shan Fault could accumulate strain rapidly and these sections are within the Tianzhu seismic gap. Although the Liupan Shan Fault accumulates strain slowly, a long time has been passed since last large earthquake, and it has accumulated high strain energy possibly. Therefore, the potential seismic risks of these segments are significantly high compared to other segments along the Haiyuan-Liupan Shan fault zone.