Field measurements of absolute gravity in East Antarctica

Abstract This paper reports the results of field-based absolute gravity measurements aimed at detecting gravity change and crustal displacement caused by glacial isostatic adjustment. The project was initiated within the framework of the 53rd Japanese Antarctic Research Expedition （JARE53）. Absolute gravity measurements, together with GPS measurements, were planned at several outcrops along the Prince Olav Coast and S6ya Coast of East Antarctica, including at Syowa Station. Since the icebreaker Shirase （AGB 5003） was unable to moor alongside Syowa Station, operations were somewhat restricted during JARE53. However, despite this setback, we were able to complete measurements at two sites： Syowa Station and Langhovde. The absolute gravity value at the Syowa Station IAGBN （A） site, observed using an FG-5 absolute gravimeter （serial number 210; FG-5 #210）, was 982 524 322.7＋0.1 ktGal, and the gravity change rate at the beginning of 2012 was -0.26 gGal.a-1. An absolute gravity value of 982 535 584.2~0.7 ktGal was obtained using a portable A-10 absolute gravimeter （serial number 017; A-10 #017） at the newly located site AGS01 in Langhovde.     

Antiviral active peptide from oyster

An active peptide against herpes virus was isolated from the enzymic hydrolysate of oyster （Crassostrea gigas） and purified with the definite direction hydrolysis technique in the order of alcalase and bromelin. The hydrolysate was fractioned into four ranges of molecular weight （〉10 kDa, 10-5 kDa, 5-1 kDa and 〈1 kDa） using ultrafiltration membranes and dialysis. The fraction of 10-5 kDa was purified using consecutive chromatographic methods including DEAE Sephadex A-25 column, Sephadex G-25 column, and high performance liquid chromatogram （HPLC） by activity-guided isolation. The antiviral effect of the obtained peptide on herpetic virus was investigated in Vero cells by observing cytopathic effect （CPE）. The result shows that the peptide has high inhibitory activity on herpetic virus.     

A bacterial pathogen infecting gametophytes of Saccharina japonica (Laminariales, Phaeophyceae)

A newly identified bacterial disease of kelp(Saccharina japonica) gametophytes was found in clone cultures.It is characterized by swollen gametophyte cells in the early period of infection followed by filamentous fading.An alginolytic marine bacterium referred to as A-1 was isolated from the diseased gametophytes.On the basis of 16S rDNA sequencing and morphological,physiological and biochemical characteristics,the bacterium was identified as a strain of the genus Alteromonas.By testing Koch’s postulates,Alteromonas sp.A-1 was further confirmed as the pathogen.The infection process was also investigated using both scanning electron and light microscopy.     

养老综合用地破题

2013年8月8日,深圳市发布《深圳市养老设施专项规划(2011-2020)》,深圳市公益性养老用地实行零地价,非公益性养老用地实行招拍挂制度.这是继北京养老用地招拍挂制度后,又一个城市养老用地创新性制度落地了. 今年2月4日,中投发展有限责任公司(以下简称"中投发展")以总价4.62亿元成功中标北京密云县一宗包含养老功能的居住用地,打响了养老综合用地实现招拍挂制度的"第一枪".该地块位于北京市密云县溪翁庄镇京密引水渠调节池东侧A-01、B-01地块(以下简称"密云A-01、B-01地块"),面积519965平方米,土地使用年限是50年,楼面价为888.5元/平方米.     

北京市延庆县两宗工业用地挂牌入市成功

2012年7月5日,延庆县两宗工业用地在北京市土地交易市场延庆县分市场挂牌交易成功。其中,延庆县永宁镇A-7地块,由金果园老农(北京食品股份有限公司)以成交价2677万元竞得;延庆县百莲路西侧地块由祺利保盈商贸有限公司以91.5万元的最高报     

Synthesis and pharmacokinetic property improvement of deuterated plinabulin 9

Plinabulin,a potent microtubule-targeting agent,is derived from marine natural diketopiperazine ‘phenylahistin'.To develop novel plinabulin analogue that could display better pharmacokinetic properties and less side effects,deuterated plinabulin 9 was synthesized and evaluated in vitro and in vivo.In comparison with plinabulin,in vivo pharmacokinetic studies indicated that the deuterated derivative 9 could alter blood circulation behavior obviously,which was proved by increased area under the plasma concentration-time curve(AUC_(0–∞)),reduced clearance(CL),and prolonged total body mean residence time(MRT).The derivative 9 also has higher inhibition rates against Bx PC-3,Jurkat and A-431 tumor cell lines as compared with its prototype plinabulin.Therefore,the deuterated compound 9 might be developed as a potential agent for different cancer treatments.     

羟基红花黄色素A-壳聚糖微球制备工艺研究

为探究羟基红花黄色素A-结合壳聚糖(HSYA-CS)微球的最佳制备工艺,采用乳化交联法制备,以微球的表观特征、粒径分布、包封率及载药量作为主要的评价指标,通过单因素考察和正交试验优化微球的最佳制备工艺。结果表明:戊二醛用量2.0 mL、交联温度50℃、投药比1∶5时,所制备的微球大小比较均一,黏连程度小,圆整度高,粒径范围2.0～4.6μm,载药量(6.53±0.42)%,包封率(68.04±0.46)%,正交设计证实上述条件下制备工艺最佳;乳化交联法制备HSYA-CS微球工艺方法稳定可行,产品性状较好,载药量和包封率较高,可为HSYA的临床应用效果的优化提供方法学借鉴。     

两种消毒剂对罗氏沼虾幼体的急性毒性试验

以半静水式试验法试验了碘伏制剂和TCCA（三氯异氰脲酸）两种消毒剂对罗氏沼虾各期幼体及仔虾的急性毒性。结果表明,不同发育期的蚤状幼体对消毒剂的耐受力不同。两种消毒剂对蚤状幼体的24hLC50、48hLC50和安全浓度分别为：碘伏制剂304×10-6～472×10-6、209×10-6～325×10-6、29．8×10-6～48．3×10-6,TCCA0．80×10-6～1．03×10-6、0．58×10-6～0．74×10-6、0．087×10-6～0．116×10-6;两种消毒剂对仔虾的24hLC50、48hLC50和安全浓度分别为：碘伏制剂499×10-6、355×10-6、53.6×10-6、TCCA1.19×10-6、0.84×10-6、0．124×10-6。在蚤状幼体阶段,ZⅪ对消毒剂的敏感性最大。     

��GPS������ɽ�ֽ�ؿDZ�����Ӧ���ʳ�

?????й??????????????1999~2013????й?????????????????2009~2013???GPS????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????1????????????????????????????????????????????????????????????й????????????????????????????????????????????????Σ?77°E?????????45×10^-9/a???????????Σ?86°E?????????10×10^-9/a;2)???????????????????????????????????????????????????????????????????50~60??×10^-9/a??????????????40~50??×10^-9/a????????GPS?????????????10~15??mm/a??????????????????;3)?????????????????????????????????38°N?????????????????????????????????????????????????????????к?????????????????????????????????????????????Σ??????????????10~20??×10^-9/a???????????????;4)??????????????????????????????????б??Σ???????????????????????????????????????????????????????????40×10^-9/a??5)????????????????λ???????????78°E??????????????30×10^-9/a??     

河南省10～11月份出让土地信息(部分)

编号位置土地面积用途出让年挂牌起始竞买保证拍卖挂牌时间(平方米)限(年)价(万元)金(万元)2005-03岳村镇中王庙村郑2008.5商服用地40挂19/10～28/10密公路北侧2005-04白寨镇白寨村郑密3067商服用地40挂19/10～28/10公路东侧2005-05平陌镇大坡村306.6商服用地40挂19/10～28/102005-06来集镇王家窝村999.9商服用地40挂19/10～28/10东城区建安大道北侧136348.7商业用地4081811500挂21/10～31/1023号住宅用地702005-6五一路北段西侧(原125040.3商业用地403751375挂21/10～31/10通用厂)住宅用地702005-9清虚街东机房街南24212商业用地403269330…     

国家重力基准点建设及精度评定

基于我国现有重力基准现状,提出加密我国重力基准的建设思路。利用国家GNSS连续运行基准站内布设的重力基准点,在我国大陆加密布测50个绝对重力点,提高我国重力基准点的分布密度。分别利用FG5和A10两台高精度绝对重力仪设备进行观测比对,获得100点次的高精度绝对重力成果;分析比较了两台设备观测的重力成果的精度统计,验证了A10观测的重力成果可基本满足高精度绝对重力观测。本工程建设的绝对重力成果可满足石油、天然气物探、地质勘探等对国家高精度重力基准点的使用需求。     

������׼վ���������IJⶨ����

???FG5????????????й?????????????????12?????????????????????????????????????????????????5??10 ^-8 ms ^-2??????????????峱????????????????????FG5??????????????Ms6.0???????????     

国家现代测绘基准体系基础设施建设一期工程绝对重力观测

介绍了2013~2014年使用A10/028和FG5/214两台绝对重力仪在国家现代测绘基准体系基础设施建设一期工程中绝对重力观测的情况,并对观测结果进行分析。结果显示,两台绝对重力仪观测结果精度及较差都在5 μGal以内,满足高精度重力基准建设的技术要求;A10/028具有一定的野外观测适应性,FG5/214对重力细微变化信号的捕获具有优势,两台绝对重力仪同期观测对于提高观测结果的可靠性和准确度具有积极的作用。     

���ػ�׼վ�����������ڱ仯����

???ü???GNSS????10??????????????????GPS????????????????????????仯???μ????????仯???????????????????????????仯????????????????????????????????С?????????м?????????п??????Ч?????????????????????????????????????????????     

�þ��������Dzⶨ���������Ǹ�ֵ�ľ��ȷ���

?????t???????????????????????????????????????????t?????????????????????????????????и??????????????????????????????????????????????????????????鲢????????????????????人???FG5-112???????????GWR-C032??????????????????????????0.1%???????????????????????????????????????????????0.2%????????????????5????????????????????????????????????????????????     

DZW重力仪非线性零漂的贝叶斯估计方法

提出一种利用重力观测数据得到DZW重力仪非线性零漂的新方法。该方法核心算法为贝叶斯公式,原理为以零漂的连续性作为先验约束条件,考虑重力观测数据浮动产生的偏差,将每个采样点零漂的均值和方差作为超参数进行求解。该算法可以重复运算,随着计算次数的增加,超参数会趋向于收敛极限,从而得到最优解。经过数据验证,该算法可以精准得到非线性零漂曲线。零漂校正后重力观测值的方差为1.595 53×10^-10 μGal²,可为DZW重力仪的测量精度提供保证。     

����̶ˮ����ˮ�Գ�����׼վ���������仯��Ӱ��

??FG5??112?????????????й?????????????硱????????? ??JZ06????????4?ξ?????????????????????????????????????????????????????????????????????1??2001??2008??3?ι?????????????????20??10^-8ms^-2???????????????????????????????????????????15.4??10^-8ms^-2??????6.7??10^-8??ms^-2????2?????????仯??????????????????????????????????仯?????0.61??10^-8ms????^-2??/a???????????λ???????-0.18cm/a??????????????????仯??????????????????????????????????????????????????????     

抗差估计在自由落体式绝对重力仪中的应用

针对自由落体式绝对重力仪中的异常数据,提出抗差参数估计的数据处理方法。对比分析传统最小二乘拟合与抗差最小二乘拟合计算的重力值,结果表明,抗差参数估计通过合理调整权重因子抑制了异常数据的影响,提高了重力测量精度。     

�й��������������������۲�������

??????й????????????????????????????FG5/232????????????2007??3??6?????й??????????12?????????????????????????????????????????3????????????????????????????????????2??10 ^-8 ms ^-2??     

��������������������ָ����ź�

?????????????????????????????????????????????????????????????????????и??????????????????????????????λ??????????????????????????÷??????????????????????g?????????????????÷?????????????10^??3?? μGal??????????????